Globuloviridae
From MicrobeWiki, the student-edited microbiology resource
A Viral Biorealm page on the family Globuloviridae
Contents |
[edit] Baltimore Classification
[edit] Higher order taxa
Viruses; dsDNA viruses, no RNA stage; Globuloviridae
[edit] Genera
[edit] Description and Significance
Globuloviridae is the fifth novel family of crenarchaeal viruses to have been introduced over the past few years, along with Fuselloviridae, Lipothrixviridae, Rudiviridae and Guttaviridae.
Globuloviridae gets its name from the Latin word "globulus", a small ball. (sources: Häring et al., Ortmann et al.)
[edit] Genome Structure
The Globuloviridae genome consists of linear, double-stranded DNA. The genome is 28, 337 nucleotides long. There are 190-bp inverted repeats at the ends of the genome. These repeats contain multiple copies of short direct repeats. The two DNA strands are probably covalently linked at their termini. (source: Häring et al.)
[edit] Virion Structure of a Globuloviridae
Members of the Globuloviridae family have spherical, enveloped virions. The virions are approximately 100 nm in diameter. (source: Häring et al.)
[edit] Reproductive Cycle of a Globuloviridae in a Host Cell
The basic replication cycle of crenarchaeal viruses, including Globuloviruses, has yet to be determined. Some viruses integrate their genome into the host cell's chromosome, while others maintain their genomes as extrachromosomal elements. Assembly and release of most known crenarchaeal viruses, with the exception of the Bicaudaviridae member ATV, do not require cell lysis. Most crenarchaeal viruses appear to set up chronic infections, either continually producing virus particles or doing so in short events resulting in growth inhibition. These long-term chronic infections are thought to be an adaptation to the extremely hot and acidic environments crenarchaeal viruses inhabit. (source: Ortmann et al.)
[edit] Viral Ecology & Pathology
Globuloviridae includes viruses that infect Thermoproteus tenax and Pyrobaculum species. (source: Ortmann et al.)
[edit] References
Häring et al. "Morphology and genome organization of the virus PSV of the hyperthermophilic archaeal genera Pyrobaculum and Thermoproteus: a novel virus family, the Globuloviridae." Virology 323.2 (2004): 233-242.
Ortmann et al. "Hot crenarchaeal viruses reveal deep evolutionary connections." Nature Reviews Microbiology 4 (2006): 520-528.
