Change in the Pharyngeal Microbial Environment after a Tonsillectomy: Difference between revisions

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<b>By Lindsey Abramson</b><br>
<b>By Lindsey Abramson</b><br>
==Introduction==
==Introduction==
</b>Tonsillectomies, the surgical removal of the tonsils, are performed on individuals with chronic tonsillitis infections, recurrent strep throat, enlarged tonsils, and other issues such as cancerous cells (Brietzke and Andreoli, 2021). The goal of this radical procedure is the eradication of bacteria assuming antibiotics have been frequently used and failed / resistance was developed (Yildizoglu et al., 2015). Streptococcus pyogenes (also called group A streptococci, or GAS) is the causative agent bacterium of strep throat, one of the leading causes that push individuals towards an elective tonsillectomy (Slonczewski et al., 2024). Although viruses are also common, other problematic bacteria include: Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, Escherichia coli, and Pseudomonas aeruginosa (Yildizoglu et al., 2015).
</b>Tonsillectomies, the surgical removal of the tonsils, are performed on individuals with chronic tonsillitis infections, recurrent strep throat, enlarged tonsils, and other issues such as cancerous cells <ref name=aa>[https://journals.sagepub.com/doi/full/10.1177/0194599820944907/Brietzke, S.E. and Andreoli, S.M., 2021. Systematic review and meta-analysis of the change in pharyngeal bacterial cultures after pediatric tonsillectomy. Otolaryngology–Head and Neck Surgery, 164(2), pp.264-270.]</ref>. The goal of this radical procedure is the eradication of bacteria assuming antibiotics have been frequently used and failed / resistance was developed <ref>[https://link.springer.com/article/10.1007/s00405-014-3434-3/Yildizoglu, U., Polat, B., Gumral, R., Kilic, A., Tosun, F. and Gerek, M., 2015. Effect of antibiotic use on bacterial flora of tonsil core in patients with recurrent tonsillitis. European Archives of Oto-Rhino-Laryngology, 272, pp.1525-1528.]</ref>. Streptococcus pyogenes (also called group A streptococci, or GAS) is the causative agent bacterium of strep throat, one of the leading causes that push individuals towards an elective tonsillectomy (Slonczewski et al., 2024). Although viruses are also common, other problematic bacteria include: Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, Escherichia coli, and Pseudomonas aeruginosa (Yildizoglu et al., 2015).


[[Image:Strep photo - CDC.jpeg|thumb|300px|right|Streptococcus pyogenes (group A Streptococcus) Photo credit: [http://www.cdc.gov/ CDC.]]]
[[Image:Strep photo - CDC.jpeg|thumb|300px|right|Streptococcus pyogenes (group A Streptococcus) Photo credit: [http://www.cdc.gov/ CDC.]]]
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Sample citations: <ref name=aa>[http://www.plosbiology.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pbio.1000005&representation=PDF Hodgkin, J. and Partridge, F.A. "<i>Caenorhabditis elegans</i> meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.]</ref>
Sample citations: <ref name=aa>[https://journals.sagepub.com/doi/full/10.1177/0194599820944907/Brietzke, S.E. and Andreoli, S.M., 2021. Systematic review and meta-analysis of the change in pharyngeal bacterial cultures after pediatric tonsillectomy. Otolaryngology–Head and Neck Surgery, 164(2), pp.264-270.]</ref>
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847443/ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.]</ref>
 
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Revision as of 01:12, 8 April 2024

By Lindsey Abramson

Introduction

Tonsillectomies, the surgical removal of the tonsils, are performed on individuals with chronic tonsillitis infections, recurrent strep throat, enlarged tonsils, and other issues such as cancerous cells [1]. The goal of this radical procedure is the eradication of bacteria assuming antibiotics have been frequently used and failed / resistance was developed [2]. Streptococcus pyogenes (also called group A streptococci, or GAS) is the causative agent bacterium of strep throat, one of the leading causes that push individuals towards an elective tonsillectomy (Slonczewski et al., 2024). Although viruses are also common, other problematic bacteria include: Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, Escherichia coli, and Pseudomonas aeruginosa (Yildizoglu et al., 2015).

Streptococcus pyogenes (group A Streptococcus) Photo credit: CDC.


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Legend/credit: Magnified 20,000X, this colorized scanning electron micrograph (SEM) depicts a grouping of methicillin resistant Staphylococcus aureus (MRSA) bacteria. Photo credit: CDC. Every image requires a link to the source.
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What is a Tonsillectomy?

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Pharyngeal Microbial Environment Pre-Tonsillectomy

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Pharyngeal Microbial Environment Post-Tonsillectomy

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Section 4

Conclusion

References



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski,at Kenyon College,2024