User:Newman5: Difference between revisions

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Interstingly, <i>H. pylori</i> infection is not a problem for everyone, and some people will go their whole lives with no effects[https://www.uptodate.com/contents/helicobacter-pylori-infection-and-treatment-beyond-the-basics/print#:~:text=pylori%2C%20is%20a%20bacterium%20that%20causes%20a%20chronic%20infection%20of,and%2C%20rarely%2C%20stomach%20tumors]. But, or the 20 - 30% of people who are infected, the consequences can be life-threatening: gastritis (stomach cancer), peptic ulcers, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Investigation reports state that at least 7 million cases of these listed diseases happen annually, worldwide[https://www.science.org/doi/10.1126/science.284.5418.1328].
Interstingly, <i>H. pylori</i> infection is not a problem for everyone, and some people will go their whole lives with no effects[https://www.uptodate.com/contents/helicobacter-pylori-infection-and-treatment-beyond-the-basics/print#:~:text=pylori%2C%20is%20a%20bacterium%20that%20causes%20a%20chronic%20infection%20of,and%2C%20rarely%2C%20stomach%20tumors]. But, or the 20 - 30% of people who are infected, the consequences can be life-threatening: gastritis (stomach cancer), peptic ulcers, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Investigation reports state that at least 7 million cases of these listed diseases happen annually, worldwide.[https://www.science.org/doi/10.1126/science.284.5418.1328]





Revision as of 16:14, 10 April 2024

The Cause of Gastric Cancer

Artisic drawing of Helicobacter pylori, depicting its rod shape with multiple flagella that enable its fast movement. Photo credit: [1]

By Alexis Newman


Helicobacter pylori is a gram-negative, flagella-bearing spiral-shaped proteobacterium1 that can grow in extremely acidic environments, like the stomach2. Its "Helico-" name derives from its helical body and because of its shape, the bacteria can make its way through the viscous lining of the stomach with help from stomach enzymes. However, once H. pylori gets colonized in the stomach, its shape can convert from the rod shape to an inactive coccoid shape3.


Helicobacter pylori is a class 1 carcinogenic bacteria, 1 being named the most carcinogenic a microbe can be and 4 being non-carcinogenic. H. pylori was determined to be a class 1 carcinogen more than 30 years ago from purely epidemiological data. This investigation showed a positive relationship between gastritis cancer and H. pylori. A couple of years after this phenomenon, in 1991, further evidence showed the prevalence of H. pylori antibodies in patients with gastric and bowel cancer 4.

Helicobacter pylori colonizes in the gastric epithelium and can proliferate. Photo credit: [2]


Interstingly, H. pylori infection is not a problem for everyone, and some people will go their whole lives with no effects[3]. But, or the 20 - 30% of people who are infected, the consequences can be life-threatening: gastritis (stomach cancer), peptic ulcers, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Investigation reports state that at least 7 million cases of these listed diseases happen annually, worldwide.[4]













Who is at risk?

Include some current research, with at least one figure showing data.

Propionibacterium acnes is a gram-positive, fairly slow-growing aerotolerant bacterium. This bacteria is typically linked to the skin condition acne vulgris, commonly known as skin acne. This species is daily commensal and highly present on healthy skin epithelium. Little is detected on the skin of adolescents, specifically those pre-pubescent. This bacterium lives on fatty acids in sebum secreted by hair sebaceous glands in hair follicles. It can also be found in the gastrointestinal biome.















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Legend/credit: Magnified 20,000X, this colorized scanning electron micrograph (SEM) depicts a grouping of methicillin resistant Staphylococcus aureus (MRSA) bacteria. Photo credit: CDC. Every image requires a link to the source.
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