Togaviridae

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Baltimore Classification

Higher order taxa

Viruses; ssRNA positive-strand viruses, no DNA stage; Togaviridae

Genera

Alphavirus, Rubivirus

Description and Significance

Genome Structure

The togavirus genome is non-segmented and contains a molecule of linear, positive-sense, single-stranded RNA. The complete genome is 9700-11800 nucleotides long. The 5'-terminus has a methylated nucleotide cap. (source: ICTVdB)

Virion Structure of a Togavirus

Togavirus virions consist of an envelope and a nucleocapsid. The virions are spheical to pleomorphic in shape, and about 70nm in diameter. Glycoprotein spikes evenly cover the surface of the virion. The genome is contained in the T=4 icosahedral capsid, which measures 40 nm in diameter. (sources: Garoff, ICTVdB)

Reproduction Cycle of a Togavirus in a Host Cell

Viral Ecology & Pathology

References

Garoff, Henrik, Mathilda Sjöberg and R. Holland Cheng. "Budding of Alphaviruses." Virus Research 106.2 (2004): 103-116.

ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/