File:Chimera Diagram.jpg
Chimera_Diagram.jpg (570 × 321 pixels, file size: 55 KB, MIME type: image/jpeg)
Construction of ChimeriVax-based vaccines. Chimeric flavivirus vaccines are constructed by replacing the genes coding for prM and E proteins from YFV 17D 204 vaccine with those of heterologous flaviviruses (DEN, WN or JE). After DNA cloning, RNA is transcribed and transfected into Vero cells to obtain chimeric viruses possessing the YFV 17D replication machinery and the external coat of the relevant heterologous flavivirus.
dx.doi.org/10.1016/j.vaccine.2009.09.098
Source: http://origin-ars.els-cdn.com/content/image/1-s2.0-S0264410X09014455-gr1.jpg
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 19:21, 8 May 2014 | | 570 × 321 (55 KB) | Helmc (talk | contribs) | Construction of ChimeriVax-based vaccines. Chimeric flavivirus vaccines are constructed by replacing the genes coding for prM and E proteins from YFV 17D 204 vaccine with those of heterologous flaviviruses (DEN, WN or JE). After DNA cloning, RNA is tra... |
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