Tomasiella immunophila

Tomasiella immunophila

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Classification

Domain Bacteria;

Phylum Pseudomonadota;

Class Gammaproteobacteria;

Order Enterobacterales;

Family Enterobacteriaceae

Species

NCBI: [1]

There is no NCBI page currently listed for the species Tomasiella Immunophila

Description and Significance

Describe the appearance, habitat, etc. of the organism, and why you think it is important.

Tomasiella immunophila is a gram-negative, rod-shaped, auxotrophic bacterium. When the species is cultured on a plate its physical characteristics appear to be smooth, moist, and translucent. The species was recently isolated from the intestinal tract of laboratory mice being investigated for microbiome symbionts at the Cleveland Clinic. (Quiche Lu et al, 2024) The mammalian microbiome maintains an internal temperature of around 37°C (98.6°F). This would classify T. immunophila as a mesophilic microbe.

Genome Structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?

Cell Structure, Metabolism and Life Cycle

Interesting features of cell structure; how it gains energy; what important molecules it produces.

Ecology and Pathogenesis

Habitat; symbiosis; biogeochemical significance; contributions to environment.

If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Lu Q, Hitch TCA, Zhou JY, Dwidar M, Sangwan N, Lawrence D, Nolan LS, Espenschied ST, Newhall KP, Han Y, Karell PE, Salazar V, Baldridge MT, Clavel T, Stappenbeck TS. A host-adapted auxotrophic gut symbiont induces mucosal immunodeficiency. Science. 2024 Sep 27;385(6716):eadk2536. doi: 10.1126/science.adk2536. Epub 2024 Sep 27. PMID: 39325906.

Author

Page authored by _____, _____, _____, & _____, students of Prof. Bradley Tolar at UNC Wilmington.