Porphyromonas Gingivalis and Gum Disease

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This illustration depicts a three-dimensional (3D), computer-generated image, of a group of Gram-positive, Streptococcus agalactiae (group B Streptococcus) bacteria. The photo credit for this image belongs to Alissa Eckert, who is a medical illustrator at the CDC.


By Babiker Higazi
To the average person, PG may simply be an abbreviation for a family-friendly movie. However, for local periodontists, PG can trigger a sense of unease. This is because Porphyromonas gingivalis, commonly known as PG, is a leading cause of gum disease worldwide. Gum disease or periodontal disease is often the result of infections in the gums and bones that support teeth. Along with tooth decay, it poses one of the most significant threats to dental health. According to a recent report, around 47% of adults over the age of 30 have some form of periodontal disease, which is more commonly found in men and people living below the federal poverty line. P. gingivalis is an anaerobic, gram-negative bacterium that has even been linked to Alzheimer's disease in world of neuroscience. To better understand this bacterium, let's trace its journey from the oral microbiota to the brain.".

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  1. ↑ 1.0 1.1 Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.
  2. ↑ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2023, Kenyon College

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