Addition of Telomerase to Somatic Cells
Telomerase is an enzyme that is able to regenerate telomeres. In humans, it is found in some tissues, such as male germ cells, activated lymphocytes, and certain types of stem cell populations. If present in somatic cells, it can turn them cancerous following mutation. Telomere shortening is one of the factors which contribute to aging so it is worthwhile to look into such an addition to develop anti-aging treatments.
Telomerase is a reverse transcriptase enzyme with its own RNA template. This makes it very similar to DNA viruses with the notable exception of capsids. Such similarities could be used to establish the idea that viruses may have fused with the cells of other organisms to give rise to telomerase in the course of evolution from the RNA world.
Compose a title for your page.
Type your exact title in the Search window, then press Go. The MicrobeWiki will invite you to create a new page with this title.
Open the BIOL 116 Class 2019 template page in "edit."
Copy ALL the text from the edit window.
Then go to YOUR OWN page; edit tab. PASTE into your own page, and edit.
At right is a sample image insertion. It works for any image uploaded anywhere to MicrobeWiki. The insertion code consists of:
Double brackets: [[
Thumbnail status: |thumb|
Pixel size: |300px|
Placement on page: |right|
Legend/credit: Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
Closed double brackets: ]]
Section 1 Genetics
Include some current research, with at least one image.
Section 2 Microbiome
Include some current research, with a second image.
Overall text length should be at least 1,000 words (before counting references), with at least 2 images. Include at least 5 references under Reference section.
- Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.
- Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.