Anaplasma phagocytophilum: Difference between revisions
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==Description and significance== | ==Description and significance== | ||
Anaplasma phagocytophilum is an intracellular obligate pathogen. It is widely distributed and can be found in North America, Europe, and Asia. Anaplasma phagocytophilum causes the disease Human granulocytic ehrlichiosis(HGE) and is most often spread through tick bites and is thus widely studied. The bacterium infects and colonizes neutrophils in host organisms, often leading to immunodeficiency diseases(1). | |||
The Human granulocytic ehrlichiosis pathogen was first described in 1994 in patients in Wisconsin and Minnesota(14). Ticks collected from the area of infection were also discovered to be carriers of the HGE pathogen(14). The infectious agent, first classified as Ehrlichia phagocytophila has recently been reclassified as Anaplasma phagocytophilum(14). | |||
==Genome structure== | ==Genome structure== | ||
Revision as of 06:12, 5 June 2007
A Microbial Biorealm page on the genus Anaplasma phagocytophilum
Classification
Higher order taxa
Bacteria; proteabacteria; alphaproteobacteria; rickettsiales; anaplasmataceae; Anaplasma; phagocytophium group (2)
Species
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NCBI: Taxonomy |
Anaplasma phagocytophilum; Anaplasma marginale; Anaplasma platys(2)
Description and significance
Anaplasma phagocytophilum is an intracellular obligate pathogen. It is widely distributed and can be found in North America, Europe, and Asia. Anaplasma phagocytophilum causes the disease Human granulocytic ehrlichiosis(HGE) and is most often spread through tick bites and is thus widely studied. The bacterium infects and colonizes neutrophils in host organisms, often leading to immunodeficiency diseases(1). The Human granulocytic ehrlichiosis pathogen was first described in 1994 in patients in Wisconsin and Minnesota(14). Ticks collected from the area of infection were also discovered to be carriers of the HGE pathogen(14). The infectious agent, first classified as Ehrlichia phagocytophila has recently been reclassified as Anaplasma phagocytophilum(14).
Genome structure
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?
Cell structure and metabolism
Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.
Ecology
Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.
Pathology
How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
Application to Biotechnology
Does this organism produce any useful compounds or enzymes? What are they and how are they used?
Current Research
Enter summaries of the most recent research here--at least three required
References
Edited by student of Rachel Larsen and Kit Pogliano
