Bacteroides fragilis: Difference between revisions

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==Introduction==
==Introduction==
<i>Bacteroides fragilis</i> is a Gram-negative bacterium found in the human colon (1). It is responsible for a large number of opportunistic infections in hospitals and contributes significantly to morbidity and mortality (2). <i>B. fragilis</i> is of interest to researchers because of its ability to evade immune responses and evolving drug resistance.
<i>Bacteroides fragilis</i> (BF) is a Gram-negative bacterium found in the human colon (1). It is responsible for a large number of opportunistic infections in hospitals and contributes significantly to morbidity and mortality (2). In addition to opportunistic infections, BF has been known to cause complications such as colorectal cancer and cholitis. (3) This bacterium is of interest to researchers because of its ability to evade immune responses and evolving drug resistance.<br><br>
 
Source 1: Kuwahara, Tomomi, et al. "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Proceedings of the National Academy of Sciences 101.41 (2004): 14919-14924.<br><br>
 
Source 2: Carolyn Redondo, Maria, et al. "Attributable mortality of bacteremia associated with the Bacteroides fragilis group." Clinical infectious diseases 20.6 (1995): 1492-1496.<br><br>
 
Source 3: Sears, Cynthia L. "Enterotoxigenic Bacteroides fragilis: a rogue among symbiotes." Clinical microbiology reviews 22.2 (2009): 349-369.<br><br>
[[Image:marburgvirus.jpg|thumb|300px|right|Colony of Marburg virus.  Transmission electron microscope image taken by Dr. Tom Geisbert]]
[[Image:marburgvirus.jpg|thumb|300px|right|Colony of Marburg virus.  Transmission electron microscope image taken by Dr. Tom Geisbert]]



Revision as of 11:35, 8 November 2019

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Introduction

Bacteroides fragilis (BF) is a Gram-negative bacterium found in the human colon (1). It is responsible for a large number of opportunistic infections in hospitals and contributes significantly to morbidity and mortality (2). In addition to opportunistic infections, BF has been known to cause complications such as colorectal cancer and cholitis. (3) This bacterium is of interest to researchers because of its ability to evade immune responses and evolving drug resistance.

Source 1: Kuwahara, Tomomi, et al. "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation." Proceedings of the National Academy of Sciences 101.41 (2004): 14919-14924.

Source 2: Carolyn Redondo, Maria, et al. "Attributable mortality of bacteremia associated with the Bacteroides fragilis group." Clinical infectious diseases 20.6 (1995): 1492-1496.

Source 3: Sears, Cynthia L. "Enterotoxigenic Bacteroides fragilis: a rogue among symbiotes." Clinical microbiology reviews 22.2 (2009): 349-369.

Colony of Marburg virus. Transmission electron microscope image taken by Dr. Tom Geisbert


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Legend/credit: Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
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Edited by James Cawthon, student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2019, Kenyon College.