https://microbewiki.kenyon.edu/index.php?title=Celiac_Disease&feed=atom&action=historyCeliac Disease - Revision history2024-03-29T08:15:26ZRevision history for this page on the wikiMediaWiki 1.39.6https://microbewiki.kenyon.edu/index.php?title=Celiac_Disease&diff=119021&oldid=prevBurrowsk at 02:12, 15 December 20152015-12-15T02:12:07Z<p></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A change in the intestinal environment of these bacteria ultimately could have the potential to influence the different colonies of gut microbiota. One study (Nistal et Al, 2012) showed that the microbiota occupying healthy adults, adults with Celiac disease undergoing treatment, and untreated adult individuals with Celiac disease had distinctly unique bacterial colonies in the small intestine. Furthermore, they found that these microbiota were also different from the microbiota of children in the same three categories [9].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A change in the intestinal environment of these bacteria ultimately could have the potential to influence the different colonies of gut microbiota. One study (Nistal et Al, 2012) showed that the microbiota occupying healthy adults, adults with Celiac disease undergoing treatment, and untreated adult individuals with Celiac disease had distinctly unique bacterial colonies in the small intestine. Furthermore, they found that these microbiota were also different from the microbiota of children in the same three categories [9].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>A similar study (Nadal I et al, 2007) found that that children affected by Celiac disease had intestinal microbiota with a “higher incidence of Gram-negative and potentially pro-inflammatory bacteria.” Apart from these differences, certain bacteria including <i> Atopobim, Clostridium histolyticum, and Faecalibacterium prausnitzii </i>, remained relatively constant in both Celiac individuals and non-Celiac individuals [10].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>A similar study (Nadal I et al, 2007) found that that children affected by Celiac disease had intestinal microbiota with a “higher incidence of Gram-negative and potentially pro-inflammatory bacteria.” Apart from these differences, certain bacteria including <i> Atopobim, Clostridium histolyticum <ins style="font-weight: bold; text-decoration: none;"></i></ins>, and <ins style="font-weight: bold; text-decoration: none;"><i></ins>Faecalibacterium prausnitzii </i>, remained relatively constant in both Celiac individuals and non-Celiac individuals [10].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>While current research efforts have uncovered more about the microbial effects of Celiac patient's dysfunctional immunity in the gut, we have yet to uncover the true meaning behind these studies. A question of which contributes to which is at hand when considering the differences in microbiota communities in the small intestine of those who are ultimately diagnosed with Celiac disease and those who are unaffected by the disease.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>While current research efforts have uncovered more about the microbial effects of Celiac patient's dysfunctional immunity in the gut, we have yet to uncover the true meaning behind these studies. A question of which contributes to which is at hand when considering the differences in microbiota communities in the small intestine of those who are ultimately diagnosed with Celiac disease and those who are unaffected by the disease.</div></td></tr>
</table>Burrowskhttps://microbewiki.kenyon.edu/index.php?title=Celiac_Disease&diff=119020&oldid=prevBurrowsk at 02:10, 15 December 20152015-12-15T02:10:57Z<p></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 02:10, 15 December 2015</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l72">Line 72:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A change in the intestinal environment of these bacteria ultimately could have the potential to influence the different colonies of gut microbiota. One study (Nistal et Al, 2012) showed that the microbiota occupying healthy adults, adults with Celiac disease undergoing treatment, and untreated adult individuals with Celiac disease had distinctly unique bacterial colonies in the small intestine. Furthermore, they found that these microbiota were also different from the microbiota of children in the same three categories [9].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A change in the intestinal environment of these bacteria ultimately could have the potential to influence the different colonies of gut microbiota. One study (Nistal et Al, 2012) showed that the microbiota occupying healthy adults, adults with Celiac disease undergoing treatment, and untreated adult individuals with Celiac disease had distinctly unique bacterial colonies in the small intestine. Furthermore, they found that these microbiota were also different from the microbiota of children in the same three categories [9].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>A similar study (Nadal I et al, 2007) found that that children affected by Celiac disease had intestinal microbiota with a “higher incidence of Gram-negative and potentially pro-inflammatory bacteria.” Apart from these differences, certain bacteria including Atopobim, Clostridium histolyticum, and Faecalibacterium prausnitzii, remained relatively constant in both Celiac individuals and non-Celiac individuals [10].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>A similar study (Nadal I et al, 2007) found that that children affected by Celiac disease had intestinal microbiota with a “higher incidence of Gram-negative and potentially pro-inflammatory bacteria.” Apart from these differences, certain bacteria including <ins style="font-weight: bold; text-decoration: none;"><i> </ins>Atopobim, Clostridium histolyticum, and Faecalibacterium prausnitzii <ins style="font-weight: bold; text-decoration: none;"></i></ins>, remained relatively constant in both Celiac individuals and non-Celiac individuals [10].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>While current research efforts have uncovered more about the microbial effects of Celiac patient's dysfunctional immunity in the gut, we have yet to uncover the true meaning behind these studies. A question of which contributes to which is at hand when considering the differences in microbiota communities in the small intestine of those who are ultimately diagnosed with Celiac disease and those who are unaffected by the disease.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>While current research efforts have uncovered more about the microbial effects of Celiac patient's dysfunctional immunity in the gut, we have yet to uncover the true meaning behind these studies. A question of which contributes to which is at hand when considering the differences in microbiota communities in the small intestine of those who are ultimately diagnosed with Celiac disease and those who are unaffected by the disease.</div></td></tr>
</table>Burrowskhttps://microbewiki.kenyon.edu/index.php?title=Celiac_Disease&diff=119019&oldid=prevBurrowsk: /* Effects on Intestinal Microbiota */2015-12-15T02:00:33Z<p><span dir="auto"><span class="autocomment">Effects on Intestinal Microbiota</span></span></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A similar study (Nadal I et al, 2007) found that that children affected by Celiac disease had intestinal microbiota with a “higher incidence of Gram-negative and potentially pro-inflammatory bacteria.” Apart from these differences, certain bacteria including Atopobim, Clostridium histolyticum, and Faecalibacterium prausnitzii, remained relatively constant in both Celiac individuals and non-Celiac individuals [10].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A similar study (Nadal I et al, 2007) found that that children affected by Celiac disease had intestinal microbiota with a “higher incidence of Gram-negative and potentially pro-inflammatory bacteria.” Apart from these differences, certain bacteria including Atopobim, Clostridium histolyticum, and Faecalibacterium prausnitzii, remained relatively constant in both Celiac individuals and non-Celiac individuals [10].</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"> </ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">While current research efforts have uncovered more about the microbial effects of Celiac patient's dysfunctional immunity in the gut, we have yet to uncover the true meaning behind these studies. A question of which contributes to which is at hand when considering the differences in microbiota communities in the small intestine of those who are ultimately diagnosed with Celiac disease and those who are unaffected by the disease.</ins></div></td></tr>
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</table>Burrowskhttps://microbewiki.kenyon.edu/index.php?title=Celiac_Disease&diff=119018&oldid=prevBurrowsk: /* Effects on Intestinal Microbiota */2015-12-15T01:57:33Z<p><span dir="auto"><span class="autocomment">Effects on Intestinal Microbiota</span></span></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Image: celiacbacteria.gif|thumb|400px|left|Differences in intestinal microbiota of Celiac patients as outlined in a study by Nadal I et al [10].]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Image: celiacbacteria.gif|thumb|400px|left|Differences in intestinal microbiota of Celiac patients as outlined in a study by Nadal I et al [10].]]</div></td></tr>
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</table>Burrowskhttps://microbewiki.kenyon.edu/index.php?title=Celiac_Disease&diff=119017&oldid=prevBurrowsk: /* Effects on Intestinal Microbiota */2015-12-15T01:57:20Z<p><span dir="auto"><span class="autocomment">Effects on Intestinal Microbiota</span></span></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Image: celiacbacteria.gif|thumb|400px|left|Differences in intestinal microbiota of Celiac patients as outlined in a study by Nadal I et al [10].]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Image: celiacbacteria.gif|thumb|400px|left|Differences in intestinal microbiota of Celiac patients as outlined in a study by Nadal I et al [10].]]</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Recent research has addressed the effects of Celiac disease on the diversity of the naturally occurring microbiota in the intestine. A healthy individual has a diverse combination of bacterial species occupying the intestine, and there is an ongoing interest in the medical community for the purpose and function of these bacteria for the human body. While widely regarded as beneficial for gut function and absorption of nutrients, many of these bacterial colonies are uncharacterized at the time being. What is known, however, is that an imbalance in these delicate communities can greatly influence human health and gut function. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Recent research has addressed the effects of Celiac disease on the diversity of the naturally occurring microbiota in the intestine. A healthy individual has a diverse combination of bacterial species occupying the intestine, and there is an ongoing interest in the medical community for the purpose and function of these bacteria for the human body. While widely regarded as beneficial for gut function and absorption of nutrients, many of these bacterial colonies are uncharacterized at the time being. What is known, however, is that an imbalance in these delicate communities can greatly influence human health and gut function. </div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A similar study (Nadal I et al, 2007) found that that children affected by Celiac disease had intestinal microbiota with a “higher incidence of Gram-negative and potentially pro-inflammatory bacteria.” Apart from these differences, certain bacteria including Atopobim, Clostridium histolyticum, and Faecalibacterium prausnitzii, remained relatively constant in both Celiac individuals and non-Celiac individuals [10].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>A similar study (Nadal I et al, 2007) found that that children affected by Celiac disease had intestinal microbiota with a “higher incidence of Gram-negative and potentially pro-inflammatory bacteria.” Apart from these differences, certain bacteria including Atopobim, Clostridium histolyticum, and Faecalibacterium prausnitzii, remained relatively constant in both Celiac individuals and non-Celiac individuals [10].</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">-</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Current Treatments & Long Term Effects==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Current Treatments & Long Term Effects==</div></td></tr>
</table>Burrowskhttps://microbewiki.kenyon.edu/index.php?title=Celiac_Disease&diff=119016&oldid=prevBurrowsk: /* Effects on Intestinal Microbiota */2015-12-15T01:57:04Z<p><span dir="auto"><span class="autocomment">Effects on Intestinal Microbiota</span></span></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 01:57, 15 December 2015</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Effects on Intestinal Microbiota==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Effects on Intestinal Microbiota==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Image: celiacbacteria.gif|thumb|<del style="font-weight: bold; text-decoration: none;">500px</del>|left|Differences in intestinal microbiota of Celiac patients as outlined in a study by Nadal I et al [10].]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Image: celiacbacteria.gif|thumb|<ins style="font-weight: bold; text-decoration: none;">400px</ins>|left|Differences in intestinal microbiota of Celiac patients as outlined in a study by Nadal I et al [10].]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Recent research has addressed the effects of Celiac disease on the diversity of the naturally occurring microbiota in the intestine. A healthy individual has a diverse combination of bacterial species occupying the intestine, and there is an ongoing interest in the medical community for the purpose and function of these bacteria for the human body. While widely regarded as beneficial for gut function and absorption of nutrients, many of these bacterial colonies are uncharacterized at the time being. What is known, however, is that an imbalance in these delicate communities can greatly influence human health and gut function. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Recent research has addressed the effects of Celiac disease on the diversity of the naturally occurring microbiota in the intestine. A healthy individual has a diverse combination of bacterial species occupying the intestine, and there is an ongoing interest in the medical community for the purpose and function of these bacteria for the human body. While widely regarded as beneficial for gut function and absorption of nutrients, many of these bacterial colonies are uncharacterized at the time being. What is known, however, is that an imbalance in these delicate communities can greatly influence human health and gut function. </div></td></tr>
</table>Burrowskhttps://microbewiki.kenyon.edu/index.php?title=Celiac_Disease&diff=119015&oldid=prevBurrowsk at 01:56, 15 December 20152015-12-15T01:56:48Z<p></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 01:56, 15 December 2015</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l63">Line 63:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Effects on Intestinal Microbiota==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Effects on Intestinal Microbiota==</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[[Image: celiacbacteria.gif|thumb|500px|left|Differences in intestinal microbiota of Celiac patients as outlined in a study by Nadal I et al [10].]]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Recent research has addressed the effects of Celiac disease on the diversity of the naturally occurring microbiota in the intestine. A healthy individual has a diverse combination of bacterial species occupying the intestine, and there is an ongoing interest in the medical community for the purpose and function of these bacteria for the human body. While widely regarded as beneficial for gut function and absorption of nutrients, many of these bacterial colonies are uncharacterized at the time being. What is known, however, is that an imbalance in these delicate communities can greatly influence human health and gut function. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Recent research has addressed the effects of Celiac disease on the diversity of the naturally occurring microbiota in the intestine. A healthy individual has a diverse combination of bacterial species occupying the intestine, and there is an ongoing interest in the medical community for the purpose and function of these bacteria for the human body. While widely regarded as beneficial for gut function and absorption of nutrients, many of these bacterial colonies are uncharacterized at the time being. What is known, however, is that an imbalance in these delicate communities can greatly influence human health and gut function. </div></td></tr>
</table>Burrowskhttps://microbewiki.kenyon.edu/index.php?title=Celiac_Disease&diff=119013&oldid=prevBurrowsk: /* Symptoms */2015-12-15T01:50:09Z<p><span dir="auto"><span class="autocomment">Symptoms</span></span></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 01:50, 15 December 2015</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Symptoms==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Symptoms==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Image: Associated.png|thumb|<del style="font-weight: bold; text-decoration: none;">400px</del>|right|Other factors influencing the presence and presentation of Celiac Disease from Medical College of Wisconsin (http://archpedi.jamanetwork.com/article.aspx?articleid=379068).]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Image: Associated.png|thumb|<ins style="font-weight: bold; text-decoration: none;">500px</ins>|right|Other factors influencing the presence and presentation of Celiac Disease from Medical College of Wisconsin (http://archpedi.jamanetwork.com/article.aspx?articleid=379068).]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>It is estimated that approximately 3 million Americans are affected by Celiac disease, but that up to 97% of that 3 million are undiagnosed [6]. The cause for such low reports of Celiac disease compared to predicted values for Celiac prevalence can likely be attributed to misinformation about the spectrum of severity of the disease symptoms as well as misdiagnosis or misunderstanding of typical gastrointestinal issues. A Celiac disease patient can experience several seemingly unrelated symptoms, and may not experience the classic array of symptoms associated with gastrointestinal stress. Symptoms also vary in severity, and often overlap with other symptoms of related and simultaneously occurring illnesses associated with Celiac [1, 2]. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>It is estimated that approximately 3 million Americans are affected by Celiac disease, but that up to 97% of that 3 million are undiagnosed [6]. The cause for such low reports of Celiac disease compared to predicted values for Celiac prevalence can likely be attributed to misinformation about the spectrum of severity of the disease symptoms as well as misdiagnosis or misunderstanding of typical gastrointestinal issues. A Celiac disease patient can experience several seemingly unrelated symptoms, and may not experience the classic array of symptoms associated with gastrointestinal stress. Symptoms also vary in severity, and often overlap with other symptoms of related and simultaneously occurring illnesses associated with Celiac [1, 2]. </div></td></tr>
</table>Burrowskhttps://microbewiki.kenyon.edu/index.php?title=Celiac_Disease&diff=119012&oldid=prevBurrowsk: /* Diagnosis */2015-12-15T01:49:48Z<p><span dir="auto"><span class="autocomment">Diagnosis</span></span></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 01:49, 15 December 2015</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Diagnosis==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Diagnosis==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Image: Iga.jpeg|thumb|<del style="font-weight: bold; text-decoration: none;">600px</del>|left|Presence of IgA anti-tTG in celiac patients (cd), celiac patients on a gluten free diet (cd/gfd) and controls (ctr) from (Dieterich et al. 1997).]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Image: Iga.jpeg|thumb|<ins style="font-weight: bold; text-decoration: none;">500px</ins>|left|Presence of IgA anti-tTG in celiac patients (cd), celiac patients on a gluten free diet (cd/gfd) and controls (ctr) from (Dieterich et al. 1997).]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
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</table>Burrowskhttps://microbewiki.kenyon.edu/index.php?title=Celiac_Disease&diff=119011&oldid=prevBurrowsk: /* Disease Pathophysiology */2015-12-15T01:49:35Z<p><span dir="auto"><span class="autocomment">Disease Pathophysiology</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 01:49, 15 December 2015</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Disease Pathophysiology==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Disease Pathophysiology==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Image: celiac_villi.jpeg|thumb|600px|right|Intestinal villi from the epithelial lining in a non-Celiac individual (top) as compared to an individual with Celiac disease (bottom). Image from the [https://celiac.org/blog/2015/03/30/biopsy-samples-diagnosis-celiac-disease/ Celiac Disease Foundation].]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Image: celiac_villi.jpeg|thumb|600px|right|Intestinal villi from the epithelial lining in a non-Celiac individual (top) as compared to an individual with Celiac disease (bottom). Image from the [https://celiac.org/blog/2015/03/30/biopsy-samples-diagnosis-celiac-disease/ Celiac Disease Foundation].]]</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Genetic influence for a Celiac patient’s flaw in immune response is located in the class of genes regarding the human leukocyte antigen, HLA-DQ2 and HLA-DQ2. These HLA genes, located on chromosome 6 in three distinct classes, are responsible for the mechanism by which anitgens are presented to immune cells. In these class II genes, the main responsibility is the outer presentation of peptides. With the correct combination of these gene types, the immune systems of Celiac patients are prone to mistakes in recognizing antigens that are foreign to the body (in this case, gliadin and other proteins) as opposed to those produced by the body (such as the tTG2 enzyme)—in essence, the cause of autoimmunity. This lack of distinction can clarify why patients with Celiac often are victims of other autoimmune diseases and problems [5].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Genetic influence for a Celiac patient’s flaw in immune response is located in the class of genes regarding the human leukocyte antigen, HLA-DQ2 and HLA-DQ2. These HLA genes, located on chromosome 6 in three distinct classes, are responsible for the mechanism by which anitgens are presented to immune cells. In these class II genes, the main responsibility is the outer presentation of peptides. With the correct combination of these gene types, the immune systems of Celiac patients are prone to mistakes in recognizing antigens that are foreign to the body (in this case, gliadin and other proteins) as opposed to those produced by the body (such as the tTG2 enzyme)—in essence, the cause of autoimmunity. This lack of distinction can clarify why patients with Celiac often are victims of other autoimmune diseases and problems [5].</div></td></tr>
</table>Burrowsk