Chlamydia Pneumoniae

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Etiology/Bacteriology

Taxonomy

| Order = Chlamydiales | Family = Chlamydiaceae | Genus = Chlamydia | Species = Chlamydia pneumoniae
|NCBI: Taxonomy Genome: Genome|}

Description

Chlamydophila pneumonia (TWAR) is a recently recognized third species of the genus Chlamydia that causes acute respiratory disease. The strain name TWAR was derived from the first conjunctival and respiratory isolates of the species (TW-183 and AR-39). [1]

Pathogenesis

Infectious Dose, Incubation, Colonization

Transmission

Clinical Presentation

Symptoms

Morbidity

Associated Diseases

Alzheimer's Disease

Atherosclerosis

Treatment

Prevention

Host Immune Response

Damage Response Framework

References

1. Grayston, J. T., C.-C. Kuo, L. A. Campbell, and S.-P. Wang. 1989. Chlamydia pneumoniae sp. nov. for Chlamydia sp. strain TWAR. Int. J. Syst. Bacteriol. 39:88–90.
2. Kuo, C., & Grayston, J. (n.d.). Chlaymydia spp. strain TWAR A newly recognized organism associated with atypical pneumonia and other respiratory infections. Clinical Microbiology Newsletter, 137-140.
3. "Chlamydophila Pneumoniae Infection." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 7 Feb. 2014. Available at: http://www.cdc.gov/pneumonia/atypical/chlamydophila.html
4. Chlamydia Pneumoniae Not Caught like You Thought (04/23/99). Available at: http://www.mc.vanderbilt.edu:8080/reporter/index.html?ID=779.
5. Humphrey, Nancy. "Chlamydia Pneumoniae Not Caught like You Thought (04/23/99)." Reporter: Vanderbilt University Medical Center. Available at: http://www.mc.vanderbilt.edu:8080/reporter/index.html?ID=779.
6. Oba, Yuji. "Chlamydial Pneumonias." : Overview, Pathophysiology, Epidemiology. 2 Nov. 2013. Available at: http://emedicine.medscape.com/article/297351-overview#a1.
7. Kuo CC, Jackson LA, Campbell LA, Grayston JT. Chlamydia pneumoniae (TWAR). Clinical Microbiology Reviews. 1995;8(4):451-461.
8. Casadevall A, Pirofski L. 2003. The Damage Response Framework of Microbial Pathogenesis. Nat Rev 1:17-24.
9. Hudson, MAP. What is the evidence for a relationship between Chlamydia pneumoniae and late-onset Alzheimer's disease? Laboratory Medicine. 2001:680–685.
10. Gérard, H. C., Dreses-Werringloer, U., Wildt, K. S., Deka, S., Oszust, C., Balin, B. J., Frey, W. H., Bordayo, E. Z., Whittum-Hudson, J. A. and Hudson, A. P. (2006), Chlamydophila (Chlamydia) pneumoniae in the Alzheimer's brain. FEMS Immunology & Medical Microbiology, 48: 355–366. doi: 10.1111/j.1574-695X.2006.00154.x
11. Mahony JB, Coombes BK. Chlamydia pneumoniae and atherosclerosis: does the evidence support a causal or contributory role? FEMS Microbiol Lett. 2001;197:1-9.
12. Farb A, Tang AL, Burke AP, Sessums L, Liang Y, et al. Sudden coronary death. Frequency of active coronary lesions, inactive coronary lesions, and myocardial infarction. Circulation. 1995;92:1701–1709.
13. Kalayoglu, M. V., & Byrne, G. I. (1998). A Chlamydia pneumoniae Component That Induces Macrophage Foam Cell Formation Is Chlamydial Lipopolysaccharide. Infection and Immunity, 66(11), 5067–5072.


Created by Erika Cummings, a student of Tyrrell Conway at the University of Oklahoma.