Chloroquine Resistance in Plasmodium falciparum

Introduction

Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.

By Edna Kemboi

At right is a sample image insertion. It works for any image uploaded anywhere to MicrobeWiki. The insertion code consists of:
Double brackets: [[
Filename: PHIL_1181_lores.jpg
Thumbnail status: |thumb|
Pixel size: |300px|
Placement on page: |right|
Legend/credit: Plasmodium falciparum life cycle [1].
Closed double brackets: ]]

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Subscript: H₂O
Superscript: Fe³⁺

Introduce the topic of your paper. What microorganisms are of interest? Habitat? Applications for medicine and/or environment?

Section 1

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Plasmodium falciparum life cycle

Figure 2. Plasmodium falciparum.[http://www.parasitesinhumans.org/plasmodium-falciparum-malaria.html

Include some current research, with at least one figure showing data.

Mechanism of Chloroquine resistance

Within the last few decades, Chloroquine was considered the best and more widely used antimalarial drug due to its effectiveness and its reasonable cost. Unfortunately, the P. falciparum parasite developed resistance to chloroquine. These resistance was mostly observed in malaria-endemic countries.

References

[1] Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.

Authored for BIOL 238 Microbiology, taught by Joan Slonczewski, 2015, Kenyon College.