Danio Rerio Genetics

From MicrobeWiki, the student-edited microbiology resource

Introduction

Zebrafish (danio rerio,) are small freshwater fish naturally found in South Asia. Belonging to the Cyprinidae family, Zebrafish are related to minnows and carps. Zebrafish have an average lifespan of 42 months and a generation time of 3 months. Due to its ease of use in laboratory procedures and its homologies to other, more complex vertebrates, Danio rerio is commonly used as a model organism for vertebrate genetics.

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Colony of Marburg virus. Transmission electron microscope image taken by Dr. Tom Geisbert


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Section 1 Development

Zebrafish reproduce through fertilization of eggs that have been spawned by the females, which release between 5 and 20 eggs per spawning. Upon fertilization, Zebrafish eggs become transparent. This transparency contributes to its use as a laboratory organism, as development is visible. Development of the Zebrafish embryo is also fairly rapid: at 24 hours, the brain, eye, and neural tube are already visible. By 5 days after fertilization, the larvae can independently swim. A short generation time of 10-12 weeks combined with the transparency of its embryos has solidified the Zebrafish’s status as a regularly used model organism..

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Section 2 Microbiome

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Edited by Hannah Schmidt, student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2019, Kenyon College.