Ectromelia virus

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Ex. Borrelia burgdorferi

Ectromelia virus (ECTV) is a zoonotic viral disease whose natural host is the mouse. It belongs to the Poxviridae family of the genus Orthopoxvirus and is among the species of Vaccinia virus. It has a linear, double-stranded DNA genome that is 209,771 bp. The virion appears in large, oval structures with a dimension of approximately 140 X 220 nm.

Characteristics of the host

What host/s is/are involved? Is there host specificity? Are there secondary reservoirs?

Ixodes tick CDC

Host-Symbiont Interaction

What kind of interaction do host and symbiont have? How is the host affected by the relationship? How does the host acquire and transmit the symbiont? Is the interaction obligate or facultative?

Molecular Insights into the Symbiosis

Describe molecular/genetic studies on the symbiosis.

Ecological and Evolutionary Aspects

What is the evolutionary history of the interaction? Do particular environmental factors play a role in regulating the symbiosis?

Recent Discoveries

Describe two findings on the symbiosis published within the last two years.

References

[Sample reference] [[1] Seemanapalli SV, Xu Q, McShan K, Liang FT. 2010. Outer surface protein C is a dissemination-facilitating factor of Borrelia burgdorferi during mammalian infection. PLoS One 5:e15830.]

Edited by [Elizabeth Stanley], students of Grace Lim-Fong

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