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Revision as of 02:18, 23 April 2020 by Stafford1 (talk | contribs) (Biochemical and neuropathologic characterization of transgenic (Tg) mice inoculated with elk chronic wasting disease (CWD) prions and treated with IND24. A, Kaplan–Meier survival curves of Tg mice expressing elk prion protein (Tg[ElkPrP]) that were i...)
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Summary

Biochemical and neuropathologic characterization of transgenic (Tg) mice inoculated with elk chronic wasting disease (CWD) prions and treated with IND24. A, Kaplan–Meier survival curves of Tg mice expressing elk prion protein (Tg[ElkPrP]) that were inoculated with elk CWD prions and treated with 3 different dosing regimens of IND24: 210 mg/kg/day from day 1 (dashed green; n = 8), as previously reported [10]; 210 mg/kg/day for 138 days, followed by 50 mg/kg/day (solid green; n = 9); or 50 mg/kg/day (dotted green; n = 8). Survival for mice treated with (V; solid red; n = 9), as previously reported [10], is also shown. Provided from the study of 2-aminothiazole to treat Chronic Wasting Disease in Transgenic Mice

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current02:18, 23 April 2020Thumbnail for version as of 02:18, 23 April 20201,010 × 710 (325 KB)Stafford1 (talk | contribs)Biochemical and neuropathologic characterization of transgenic (Tg) mice inoculated with elk chronic wasting disease (CWD) prions and treated with IND24. A, Kaplan–Meier survival curves of Tg mice expressing elk prion protein (Tg[ElkPrP]) that were i...

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