Genetics of Amyotrophic Lateral Sclerosis: Difference between revisions

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[[Image:10815_lores.jpg|thumb|300px|right|Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the [https://phil.cdc.gov/details_linked.aspx?pid=10815 CDC].]]
[[Image:10815_lores.jpg|thumb|300px|right|Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the [https://phil.cdc.gov/details_linked.aspx?pid=10815 CDC].]]


Amyopathic lateral sclerosis (ALS) is an age-related progressive neurodegenerative disorder of both upper motor neurons (UMN) and lower motor neurons (LMN). <ref> name = Bryan J. Traynor, M. (2000, August 01). Clinical Features of Amyotrophic Lateral Sclerosis According to the El Escorial and Airlie House Diagnostic Criteria. Retrieved December 08, 2020, from https://jamanetwork.com/journals/jamaneurology/article-abstract/777262</ref> ALS is also referred to as Motor Neuron Disease (MND) in European countries such as the United Kingdom the disease affects motor neuron functions in the human motor system.<ref> name = Fang, F., Kamel, F., Sandler, D., Sparén, P., & Ye, W. (2008, March 25). Maternal Age, Exposure to Siblings, and Risk of Amyotrophic Lateral Sclerosis. Retrieved December 08, 2020, from https://academic.oup.com/aje/article/167/11/1281/131930</ref>
Amyopathic lateral sclerosis (ALS) is an age-related progressive neurodegenerative disorder of both upper motor neurons (UMN) and lower motor neurons (LMN).<ref> Bryan J. Traynor, M. (2000, August 01). Clinical Features of Amyotrophic Lateral Sclerosis According to the El Escorial and Airlie House Diagnostic Criteria. Retrieved December 08, 2020, from https://jamanetwork.com/journals/jamaneurology/article-abstract/777262</ref> ALS is also referred to as Motor Neuron Disease (MND) in European countries such as the United Kingdom the disease affects motor neuron functions in the human motor system.<ref>Fang, F., Kamel, F., Sandler, D., Sparén, P., & Ye, W. (2008, March 25). Maternal Age, Exposure to Siblings, and Risk of Amyotrophic Lateral Sclerosis. Retrieved December 08, 2020, from https://academic.oup.com/aje/article/167/11/1281/131930</ref>




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==Section 1: Genetics of ALS==
==Section 1: Genetics of ALS==
Include some current research, with at least one image.<br><br>
Include some current research, with at least one image.<br><br>


Sample citations: <ref>[http://www.plosbiology.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pbio.1000005&representation=PDF Hodgkin, J. and Partridge, F.A. "<i>Caenorhabditis elegans</i> meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.]</ref>
 
<ref>[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847443/ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.]</ref>
<br><br>A citation code consists of a hyperlinked reference within "ref" begin and end codes.


==Section 2: Neuroepigenetics of ALS==
==Section 2: Neuroepigenetics of ALS==

Revision as of 13:19, 8 December 2020

Introduction

Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.

Amyopathic lateral sclerosis (ALS) is an age-related progressive neurodegenerative disorder of both upper motor neurons (UMN) and lower motor neurons (LMN).[1] ALS is also referred to as Motor Neuron Disease (MND) in European countries such as the United Kingdom the disease affects motor neuron functions in the human motor system.[2]




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Filename: PHIL_1181_lores.jpg
Thumbnail status: |thumb|
Pixel size: |300px|
Placement on page: |right|
Legend/credit: Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
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Section 1: Genetics of ALS

Include some current research, with at least one image.


Section 2: Neuroepigenetics of ALS

Include some current research, with a second image.

Section 3: Gut Microbiome

Conclusion

Overall text length should be at least 1,000 words (before counting references), with at least 2 images. Include at least 5 references under Reference section.


References

  1. Bryan J. Traynor, M. (2000, August 01). Clinical Features of Amyotrophic Lateral Sclerosis According to the El Escorial and Airlie House Diagnostic Criteria. Retrieved December 08, 2020, from https://jamanetwork.com/journals/jamaneurology/article-abstract/777262
  2. Fang, F., Kamel, F., Sandler, D., Sparén, P., & Ye, W. (2008, March 25). Maternal Age, Exposure to Siblings, and Risk of Amyotrophic Lateral Sclerosis. Retrieved December 08, 2020, from https://academic.oup.com/aje/article/167/11/1281/131930


Edited by Smrami Patel, student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2020, Kenyon College.