Genetics of Amyotrophic Lateral Sclerosis

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Introduction

Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.

Amyopathic lateral sclerosis (ALS) is an age-related progressive neurodegenerative disorder of both upper motor neurons (UMN) and lower motor neurons (LMN). [1] ALS is also referred to as Motor Neuron Disease (MND) in European countries such as the United Kingdom the disease affects motor neuron functions in the human motor system.[2]




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Legend/credit: Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the CDC.
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Section 1: Genetics of ALS

Include some current research, with at least one image.

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Section 2: Neuroepigenetics of ALS

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Section 3: Gut Microbiome

Conclusion

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References

  1. ↑ name = Bryan J. Traynor, M. (2000, August 01). Clinical Features of Amyotrophic Lateral Sclerosis According to the El Escorial and Airlie House Diagnostic Criteria. Retrieved December 08, 2020, from https://jamanetwork.com/journals/jamaneurology/article-abstract/777262
  2. ↑ name = Fang, F., Kamel, F., Sandler, D., Sparén, P., & Ye, W. (2008, March 25). Maternal Age, Exposure to Siblings, and Risk of Amyotrophic Lateral Sclerosis. Retrieved December 08, 2020, from https://academic.oup.com/aje/article/167/11/1281/131930
  3. ↑ Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.
  4. ↑ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.


Edited by Smrami Patel, student of Joan Slonczewski for BIOL 116 Information in Living Systems, 2020, Kenyon College.

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