Granulibacter bethesdensis

A Microbial Biorealm page on the genus Granulibacter bethesdensis

Classification

Higher order taxa

Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales; Acetobacteracease; Granulibacter

Species

Granulibacter Bethesdensis

Description and significance

Granulibacter bethesdensis is a new speices. It is a gram-negative, catalase-positive and oxidase-negative pathogenic bactrium, whch causes chronic granulomatous disease; it is rod-shaped, thermophilic, and aerobic.

Genome structure

Granulibacter bethesdensis has 2708355 nucleotides, 2498 genes,0 pseudogene, 2437 proteins, 61 structural RNAs, and circular DNA. Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?

Cell structure and metabolism

Granulibacter bethesdensis is usually found in soil and plants, and rarely in human. It breaks down ethanol and produces acetic acid; it may be industrialized in producing vinegar.

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

One of the current main researches is to study the epidemiology and pathogenicity of granulibacter bethesdensis.

Enter summaries of the most recent research here--at least three required

References

David E. Greenberg1,, Stephen F. Porcella2,, Frida Stock3, Alexandra Wong3, Patricia S. Conville3, Patrick R. Murray3, Steven M. Holland1 and Adrian M. Zelazny3 . "Granulibacter bethesdensis gen. nov., sp. nov., a distinctive pathogenic acetic acid bacterium in the family Acetobacteraceae".International Journal of Systematic and Evolution Microbiology 56 (November 2006), 2609-2616.

David E Greenberg,1 Li Ding,1 Adrian M Zelazny,2 Frida Stock,2 Alexandra Wong,2 Victoria L Anderson,1 Georgina Miller,3 David E Kleiner,4 Allan R Tenorio,5 Lauren Brinster,3 David W Dorward,6 Patrick R Murray,2 and Steven M Holland1. "A Novel Bacterium Associated with Lymphadenitis in a Patient with Chronic Granulomatous Disease". PLoS Pathog. 2006 April; 2(4): e28. Published online 2006 April 14. doi: 10.1371/journal.ppat.0020028

KEGG, April 2007, Kyoto Encyclopedia of Genes and Genomes, http://www.genome.jp/kegg

David Fredricks and Lalita Ramakrishnan. "The Acetobacteraceae: Extending the Spectrum of Human Pathogens". PLoS Pathog. 2006 April; 2(4): e36. Published online 2006 April 28. doi: 10.1371/journal.ppat.0020036

Edited by student of Rachel Larsen and Kit Pogliano