H. influenzae: Difference between revisions
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Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? | Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? | ||
Haemophilus influenzae is a non-motile Gram-negative coccobacillus first identifed by Dr. Robert Pfeiffer in 1892. the genome structure of haemophilus influenzae consist of 1,830,138 nucleotide base pairs and it is estimated to have approximately 1740 genes and was the first genome to be sequenced and assembled in a free living organism. it consist of a single circular chromosome replicon which has coding regions for rRNA, tRNA and proteins. they identified that the four nucleotides are not used at equal frequency across the genome as A and T are more common than C and G. there are sequence uncertainties in the genome as other symbols occur in the sequence and corresponds to positions in the sequence that are not clearly one base or another. | Haemophilus influenzae is a non-motile Gram-negative coccobacillus first identifed by Dr. Robert Pfeiffer in 1892. the genome structure of haemophilus influenzae consist of 1,830,138 nucleotide base pairs and it is estimated to have approximately 1740 genes and was the first genome to be sequenced and assembled in a free living organism. it consist of a single circular chromosome replicon which has coding regions for rRNA, tRNA and proteins. they identified that the four nucleotides are not used at equal frequency across the genome as A and T are more common than C and G. there are sequence uncertainties in the genome as other symbols occur in the sequence and corresponds to positions in the sequence that are not clearly one base or another. other bases which are seen in the sequence are Y, R, K, M, S, W and N. (Computational Genomics) | ||
==Cell Structure, Metabolism and Life Cycle== | ==Cell Structure, Metabolism and Life Cycle== | ||
Revision as of 18:23, 17 April 2011
Classification
Haemophilus influenzae is found along the bacteria lineage: kindgom name:Bacteria, phylum name:Proteobacteria,class name:Gamma Proteobacteria;order:Pasteurellales, family name:Pasteurellaceae; and genus name Haemophilus. the specie name is haemophilus influenzae
hamophilus influenzae has other names by which it can be identifed as it was formely known as the Pfeiffer's bacillus or Bacillus influenzae. it is also known as haemophilus meningitidis,Mycobacterium influenzae,Influenza-bacillus to name a few.
other species that fall under the same genus name are: haemophilus ducreyi and haemophilus influenzae aegyptius
Domain; Phylum; Class; Order; family [Others may be used. Use NCBI link to find]
Species
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NCBI: Taxonomy |
Genus species
Description and Significance
Describe the appearance, habitat, etc. of the organism, and why you think it is important.
Genome Structure
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?
Haemophilus influenzae is a non-motile Gram-negative coccobacillus first identifed by Dr. Robert Pfeiffer in 1892. the genome structure of haemophilus influenzae consist of 1,830,138 nucleotide base pairs and it is estimated to have approximately 1740 genes and was the first genome to be sequenced and assembled in a free living organism. it consist of a single circular chromosome replicon which has coding regions for rRNA, tRNA and proteins. they identified that the four nucleotides are not used at equal frequency across the genome as A and T are more common than C and G. there are sequence uncertainties in the genome as other symbols occur in the sequence and corresponds to positions in the sequence that are not clearly one base or another. other bases which are seen in the sequence are Y, R, K, M, S, W and N. (Computational Genomics)
Cell Structure, Metabolism and Life Cycle
Interesting features of cell structure; how it gains energy; what important molecules it produces.
Ecology and Pathogenesis
Habitat; symbiosis; biogeochemical significance; contributions to environment.
If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
References
DNA uptake signal sequences in naturally transformable bacteria.
Smith HO, Gwinn ML, Salzberg SL.
Res Microbiol. 1999 Nov-Dec; 150(9-10):603-16.
Author
Page authored by _____, student of Prof. Doreen Cunningham at Saint Augustine's College.
