Haemophilus pertussis (Whooping Cough)

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Microbiology in Italy[1]
Haemophilus pertussis[2]

Etiology/Bacteriology

Taxonomy

| Domain = Bacteria | Phylum = Proteobacteria | Class = Betaproteobacteria | Order = Burkholderiales | Family = Alcaligenaceae | Genus = Bordetella | species = pertussis

NCBI: Taxonomy Genome: [3]

Description

Pathogenesis

Transmission

Infectious dose, incubation, and colonization

Virulence factors

Clinical features

Diagnosis

Treatment

Apnoeic or cyanotic cases of infants under 6 months should be taken care of in hospitals. Any suspicion of symptoms of whooping cough should be a sign to excuse children from school and receive antibiotic treatments within 3 weeks of illness. Clarithromycin and azithromycin are the preferred antibiotics for babies from birth to 1 year old. Adults can also take these antibiotics. However, co-trimoxazole can be used if the individual who cannot tolerate macrolides. Pregnant women who already has the disease are treated with erythromycin to prevent transmission to infant. Spasms are treated with mild sedation, and cyanosis is treated with administration of oxygen. [2]

Prevention

Host Immune Response

References

  1. Oakley S, and Kilcoyne A. The whooping cough epidemic: prevention and treatment. Practice Nursing. 2012 Oct. 604-7
  2. Treatment of Whooping Cough. General Practice Notebook (online)
  3. Pluta R.M. Pertussis. JAMA. 2010 Aug. (online)