Difference between revisions of "Haemophilus somnus"

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==Pathology==
 
==Pathology==
 
How does this organism cause disease?  Human, animal, plant hosts?  Virulence factors, as well as patient symptoms.
 
How does this organism cause disease?  Human, animal, plant hosts?  Virulence factors, as well as patient symptoms.
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Haemophilus somnus causes a wide variety of systemiatic diseases ranging from penumonia , abortion, arthritis, myocarditis, and septimia.  It spreads throughout cattle herds in an elusive matter and become a major issue before it is even detected.  There are 3 primary forms that h. somnus is able to assume: reproductive tract,urinary tract, respiratory tract form.
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1.Reproductive and urinary tract form
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In this form, h. somnus attacks the reproductive tract of pregnant cows, which may lead to the death of a fetus and subsequent abortion.  It also causes the infection of the uterus and has been found in the urinary tract and prepuce of bulls which contracted the organism during mating.  The excretion of uterine or vaginal discharge and urine of the infected animal also acts to transmit the disease to other unaffected cattle in close proximity, which become exposed to the organism by sniffing or by physically being contacted with the discharge.  This can then lead to the respiratory form
  
 
==Application to Biotechnology==
 
==Application to Biotechnology==

Revision as of 15:16, 3 May 2007

A Microbial Biorealm page on the genus Haemophilus somnus

Classification

Higher order taxa

Haemophilus somnus is a bacteria under the phylum proteobacteria. It is of the class, Gammaproteobacteria, in the order Pasteurellales, which typically live on the mucosal surface of birds and mammals, most notably in the upper respiratory tract. They are also of the family Pasteurellaceae. genus Histophilus

 Use NCBI link to find]

Species

species somnus Lineage Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Histophilus

NCBI: Taxonomy

Genus species

Description and significance

Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. Include a picture or two (with sources) if you can find them.

Genome Structure

Their genome (seq: RS: NC_008309) consists of a circular chromosome containing 2007700 base pairs and a plasmid(pHS129) is approximately 5178 bp in length. It is made up of roughly 34% GC content and 66% AT and contains genes coding for approximately 1798 different proteins and 65 RNA genes.

Cell structure and metabolism

Haemophilus somnus is a rod-shaped, gram negative bacteria. It is a facultative pathogen that has LOS is its major outer membrane component. It also contains bacterial transferrin receptors, which is a structure that contributes to its virulence (typically in cattle). Haemophilus has no flagella and is catalase negative.

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Haemophilus somnus causes a wide variety of systemiatic diseases ranging from penumonia , abortion, arthritis, myocarditis, and septimia. It spreads throughout cattle herds in an elusive matter and become a major issue before it is even detected. There are 3 primary forms that h. somnus is able to assume: reproductive tract,urinary tract, respiratory tract form.

1.Reproductive and urinary tract form In this form, h. somnus attacks the reproductive tract of pregnant cows, which may lead to the death of a fetus and subsequent abortion. It also causes the infection of the uterus and has been found in the urinary tract and prepuce of bulls which contracted the organism during mating. The excretion of uterine or vaginal discharge and urine of the infected animal also acts to transmit the disease to other unaffected cattle in close proximity, which become exposed to the organism by sniffing or by physically being contacted with the discharge. This can then lead to the respiratory form

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

Enter summaries of the most recent research here--at least three required

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Edited by student of Rachel Larsen and Kit Pogliano