Mouse Mammary Tumor Virus: Difference between revisions

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==Virion Structure of MMTV==
==Virion Structure of MMTV==
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<br>The MMTV virion is a B-type particle containing a genomic RNA dimer, encapsidated by NC proteins in the form of a helical nucleoprotein (RNP). Surrounding the genomic material is an apparently icosahedral capsid, formed by CA proteins. The capsid is bound to the envelope by the matrix protein MA. Finally, the viral envelope is characterized by several spikes, composed of a transmembrane protein and a surface protein.


==Reproductive Cycle of MMTV==
==Reproductive Cycle of MMTV==

Revision as of 18:17, 16 September 2008

A Viral Biorealm page on the family Mouse Mammary Tumor Virus

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description [link].



Baltimore Classification


Group VI. RNA Reverse Transcribing Viruses (Retroviruses)

Higher order categories


Order: Unassigned
Family: Retroviridae
Subfamily: Orthoretrovirinae
Genus: Betaretrovirus

Description and Significance


Mouse Mammary Tumor Virus (MMTV)was reported for the first time in 1933 by the Jackson Memorial Laboratory. It was initially identified by studying inbred mouse strains characterized by a high incidence of mammary tumor.

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Genome Structure


Genome structure

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Virion Structure of MMTV


The MMTV virion is a B-type particle containing a genomic RNA dimer, encapsidated by NC proteins in the form of a helical nucleoprotein (RNP). Surrounding the genomic material is an apparently icosahedral capsid, formed by CA proteins. The capsid is bound to the envelope by the matrix protein MA. Finally, the viral envelope is characterized by several spikes, composed of a transmembrane protein and a surface protein.

Reproductive Cycle of MMTV


info

info

info

Viral Ecology & Pathology


pathology.

cancer

info

References

references Page authored for BIOL 375 Virology, September 2008