Mycobacterium leprae -- Leprosy

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Pathogenic Microbiology in Italy [1]
"Mycobacterium leprae" globi in patient. [2]

Etiology/Bacteriology

Taxonomy

| Domain = Bacteria | Phylum = Actinobacteria | Class = Actinobacteridae | Order = Actinomycetales | Suborder = Corynebacterineae | Family = Mycobacteriaceae | Genus = Mycobacterium | Species = M. leprae |

NCBI: Taxonomy Genome: Mycobacterium leprae

Description

Pathogenesis

Transmission

Infectious dose, incubation, and colonization

Epidemiology

Map of new leprosy cases annually (2010) From: Leprosymission.org [3]

Virulence factors

Waxy exterior

Iron utilization

Macrophage invasion

Schwann cell invasion

Drug resistance

Clinical features

Clinical manifestations of "Mycobacterium leprae" infection. From: Bio.davidson.edu [4]

Classification

Type 1

Type 2

Lucio Phenomenon

Diagnosis

Treatment

Before and after Multidrug Therapy (MDT) From: Stlukesleprosyhospital.org [5]

Prevention

Vaccination

Eradication attempts

Immune Response

Protective immunity and susceptibility

Host defense

Bacterial evasion

References

1 Conway, Tyrrell. “Genus conway”. “Microbe Wiki” 2013. Volume 1. p. 1-2.

Created by Gracen Conway, student of Tyrrell Conway at the University of Oklahoma.