Nanoarchaeum equitans: Difference between revisions

From MicrobeWiki, the student-edited microbiology resource
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==Cell structure and metabolism==
==Cell structure and metabolism==
Interesting features and/or cell structures.  How it gains energy. Important molecules it produces.
Interesting features and/or cell structures.  How it gains energy. Important molecules it produces.
''Nanoarchaeum equitans'' is spherical and extremely small, with a size of only 400 nm in diameter.  This marks it as one of the smallest known living cells.  It has no flagella and can only grow attached to the specific archaeal host ''Ignicoccus hospitalis''. 
Due to the lack of genes encoding several vital metabolic pathways, ''Nanoarchaeum equitans'' relies on its host to acquire many biomolecules such as lipids, amino acids, and nucleotides.


==Ecology==
==Ecology==

Revision as of 23:06, 28 August 2007

A Microbial Biorealm page on the genus Nanoarchaeum equitans

Classification

Higher order taxa

Archaea; Nanoarchaeota; Nanoarchaeum

Species

Nanoarchaeum equitans

Description and significance

Nanoarchaeum equitans, which means "riding the fire sphere", is a hyperthermophile that also acts as an obligate symbiont to the archaea Ignicoccus hospitalis. It is spherical and is only 400 nm in diameter, making it one of the smallest known living organisms. It is also the only known archaeal parasite.

It was first discovered in 2002 in an undersea hydrothermal vent off the coast of Iceland by Karl Stetter. It was first seen as tiny dots on the surface of Ignicoccus hospitalis. Its genome is extremely small, making it one of the smallest non-viral genomes ever sequenced. The significance of its genome was that ss rRNA-based sequencing comparisons placed its branching point early in the archaeal lineage, representing the new archaeal kingdom Nanoarchaeota. As such, it is the only known member of this lineage.

Genome structure

Nanoarchaeum equitans has one of the smallest genomes of any sequenced microbe with only 490,885 base pairs. It was first sequenced in 2003. This sequenced genome was of strain Kin4-M which was found in hot-water geysers on the ocean floor near Iceland.

The genome has one circular chromosome, about 550 protein genes, 46 RNA genes, and has a GC content of %31.6. The genome encodes the machinery for information processing and repair, but lacks genes for lipid, cofactor, amino acid, or nuleotide biosynthesis. It is also one of the most compact genomes, with 95% of the DNA used to encode proteins or stable RNAs. Unlike the similarly small genomes of bacterial parasites that are undergoing reductive evolution, Nanoarchaeum equitans has few pseudogenes or extensive regions of noncoding DNA.

Cell structure and metabolism

Interesting features and/or cell structures. How it gains energy. Important molecules it produces.

Nanoarchaeum equitans is spherical and extremely small, with a size of only 400 nm in diameter. This marks it as one of the smallest known living cells. It has no flagella and can only grow attached to the specific archaeal host Ignicoccus hospitalis.

Due to the lack of genes encoding several vital metabolic pathways, Nanoarchaeum equitans relies on its host to acquire many biomolecules such as lipids, amino acids, and nucleotides.

Ecology

Interactions with other organisms, contributions to the environment, effect on the environment.

Pathology

Does this organism cause disease? Does it have a host? Virulence factors as well as patient symptoms.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?


Current Research

Summaries of recent research here. At least 3 required.


References

Edited by Robert Rishwain, student of Rachel Larsen and Kit Pogliano