Difference between revisions of "Neisseria elongata"

From MicrobeWiki, the student-edited microbiology resource
Line 17: Line 17:
  
 
==Description and significance==
 
==Description and significance==
<i>Neisseria elongata</i>, formerly known as Centers for Disease Control (CDC) group M6, was described by Bovre and Holten in 1970 as a gram-negative, rod-shaped bacterium of the family Neisseriaceae. It is found the oral bacterial flora of the human pharynx and throat (2). <i>N. elongata</i> consists of three subspecies, <i>N. elongata</i> subsp. <i>elongata,</i> <i>N. elongata</i> subsp. <i>glycolytica,</i> and <i>N. elongata</i> subsp. <i>nitroreducens,</i> in which are separated based on their biochemical differences (3). Although these subspecies of <i>N. elongata</i> were previously believed to be nonpathogenic to humans, recent case studies have indicated that all three <i>N. elongata</i> subspecies are associated with human disease, typically endocarditis and osteomyelitis (2).  
+
<i>Neisseria elongata</i>, formerly known as Centers for Disease Control (CDC) group M6, was described by Bovre and Holten in 1970 as a gram-negative, rod-shaped bacterium of the family Neisseriaceae, where it is found in the oral bacterial flora of the human pharynx and throat (2). <i>N. elongata</i> consists of three subspecies, <i>N. elongata</i> subsp. <i>elongata,</i> <i>N. elongata</i> subsp. <i>glycolytica,</i> and <i>N. elongata</i> subsp. <i>nitroreducens,</i> in which are separated based on their biochemical differences (3). Although these subspecies of <i>N. elongata</i> were previously believed to be nonpathogenic to humans, recent case studies from patients suffering for endocarditis, have indicated that all three <i>N. elongata</i> subspecies are associated with human disease, particularly endocarditis and osteomyelitis (2).  
  
Although the <i>N. elongata</i> genome has not yet been sequenced, the importance of sequencing its genome will provide information on the three <i>N. elongata</i> subspecies and will help distinguish their pathogenic roles in endocarditis and osteomyelitis. Before their pathogenic roles were discovered, <i>N. elongata</i> subsp. <i>elongata</i> and <i>N. elongata</i> subsp. <i>glycolytica</i> were considered to be transient colonizers of the human upper respiratory tract and urogentical tract (3). Thus, the sequencing of their genomes could possibly provide further insight into the difference and similarities in the factors behind their metabolism and virulent features.
+
Although the <i>N. elongata</i> genome has not yet been sequenced, the importance of sequencing its genome will provide information on the three <i>N. elongata</i> subspecies that could possibly assist in distinguishing their pathogenic roles in endocarditis and osteomyelitis. Before their pathogenic roles were discovered, <i>N. elongata</i> subsp. <i>nitroreducens</i> was the first subspecies to be discovered as pathogenic, while <i>N. elongata</i> subsp. <i>elongata</i> and <i>N. elongata</i> subsp. <i>glycolytica</i> were considered to be transient colonizers of the human upper respiratory tract and urogentical tract (3). Thus, the sequencing of their genomes could possibly provide further insight into the differences and similarities involved in the factors influencing their metabolism and virulent features.
  
 
==Genome structure==
 
==Genome structure==

Revision as of 03:14, 27 August 2007

A Microbial Biorealm page on the genus Neisseria elongata

Classification

Higher order taxa

root; cellular organisms; Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Neisseria

Species

NCBI: Taxonomy

Neisseria elongata

Description and significance

Neisseria elongata, formerly known as Centers for Disease Control (CDC) group M6, was described by Bovre and Holten in 1970 as a gram-negative, rod-shaped bacterium of the family Neisseriaceae, where it is found in the oral bacterial flora of the human pharynx and throat (2). N. elongata consists of three subspecies, N. elongata subsp. elongata, N. elongata subsp. glycolytica, and N. elongata subsp. nitroreducens, in which are separated based on their biochemical differences (3). Although these subspecies of N. elongata were previously believed to be nonpathogenic to humans, recent case studies from patients suffering for endocarditis, have indicated that all three N. elongata subspecies are associated with human disease, particularly endocarditis and osteomyelitis (2).

Although the N. elongata genome has not yet been sequenced, the importance of sequencing its genome will provide information on the three N. elongata subspecies that could possibly assist in distinguishing their pathogenic roles in endocarditis and osteomyelitis. Before their pathogenic roles were discovered, N. elongata subsp. nitroreducens was the first subspecies to be discovered as pathogenic, while N. elongata subsp. elongata and N. elongata subsp. glycolytica were considered to be transient colonizers of the human upper respiratory tract and urogentical tract (3). Thus, the sequencing of their genomes could possibly provide further insight into the differences and similarities involved in the factors influencing their metabolism and virulent features.

Genome structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?

Cell structure and metabolism

Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

Enter summaries of the most recent research here--at least three required

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Edited by student of Rachel Larsen