https://microbewiki.kenyon.edu/index.php?title=Neoehrlichia_mikurensis&feed=atom&action=history
Neoehrlichia mikurensis - Revision history
2024-03-29T01:08:45Z
Revision history for this page on the wiki
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https://microbewiki.kenyon.edu/index.php?title=Neoehrlichia_mikurensis&diff=119757&oldid=prev
BarichD at 15:41, 22 February 2016
2016-02-22T15:41:59Z
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BarichD
https://microbewiki.kenyon.edu/index.php?title=Neoehrlichia_mikurensis&diff=119555&oldid=prev
BarichD at 19:30, 5 February 2016
2016-02-05T19:30:57Z
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BarichD
https://microbewiki.kenyon.edu/index.php?title=Neoehrlichia_mikurensis&diff=119549&oldid=prev
BarichD at 19:24, 5 February 2016
2016-02-05T19:24:35Z
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Edited by Ryan Whelan, student of Dr. Lisa R. Moore, University of Southern Maine, Department of Biological Sciences, http://www.usm.maine.edu/bio</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Edited by Ryan Whelan, student of Dr. Lisa R. Moore, University of Southern Maine, Department of Biological Sciences, http://www.usm.maine.edu/bio</div></td></tr>
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BarichD
https://microbewiki.kenyon.edu/index.php?title=Neoehrlichia_mikurensis&diff=88057&oldid=prev
MooreL: /* Genome structure */
2013-05-18T01:58:00Z
<p><span dir="auto"><span class="autocomment">Genome structure</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 01:58, 18 May 2013</td>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>The 16S rRNA and groEL genes have been used to identify this species on numerous occasion. <sup>[[#References|[6]]]</sup> The 16S gene is 1,426 bp in length and the groEL gene is 1,233 bp in length. </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>The 16S rRNA and groEL genes have been used to identify this species on numerous occasion. <sup>[[#References|[6]]]</sup> The 16S <ins style="font-weight: bold; text-decoration: none;">rRNA </ins>gene is 1,426 bp in length and the groEL gene is 1,233 bp in length.</div></td></tr>
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MooreL
https://microbewiki.kenyon.edu/index.php?title=Neoehrlichia_mikurensis&diff=88056&oldid=prev
MooreL: /* Metabolism */
2013-05-18T01:57:03Z
<p><span dir="auto"><span class="autocomment">Metabolism</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 01:57, 18 May 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Metabolism==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Metabolism==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Not much is known about the metabolism of <I>Ca.</I> N. mikurensis other than it is a facultative anaerobe. Blood samples of people infected with the bacterium have been gathered in aerobic and anaerobic flasks, and both scenarios presented the same <del style="font-weight: bold; text-decoration: none;">16s </del>rRNA sequence. <sup>[[#References|[4]]]</sup></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Not much is known about the metabolism of <I>Ca.</I> N. mikurensis other than it is a facultative anaerobe. Blood samples of people infected with the bacterium have been gathered in aerobic and anaerobic flasks, and both scenarios presented the same <ins style="font-weight: bold; text-decoration: none;">16S </ins>rRNA sequence. <sup>[[#References|[4]]]</sup></div></td></tr>
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MooreL
https://microbewiki.kenyon.edu/index.php?title=Neoehrlichia_mikurensis&diff=86392&oldid=prev
Ryan.whelan at 03:53, 2 May 2013
2013-05-02T03:53:45Z
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Ecology==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Ecology==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><I>Ca.</I> N. mikurensis tends to concentrate in the liver and spleen endothelium cells of small rodents and these small rodents transfer the bacterium to <I>Ixodes ricinus</I> tick larvae, as these rodents are their main food source. These central and eastern European <I>I. ricinus</I> ticks act as the vector for the microbe most commonly, which can infect humans via a tick bite. <sup>[1]</sup> Studies have suggested that approximately 8.1% of <I>I. ricinus</I> ticks may have the bacterium present. <sup>[[#References|[5]]]</sup></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><I>Ca.</I> N. mikurensis tends to concentrate in the liver and spleen endothelium cells of small rodents and these small rodents transfer the bacterium to <I>Ixodes ricinus</I> tick larvae, as these rodents are their main food source. These central and eastern European <I>I. ricinus</I> ticks act as the vector for the microbe most commonly, which can infect humans via a tick bite. <sup><ins style="font-weight: bold; text-decoration: none;">[[#References|</ins>[1<ins style="font-weight: bold; text-decoration: none;">]]</ins>]</sup> Studies have suggested that approximately 8.1% of <I>I. ricinus</I> ticks may have the bacterium present. <sup>[[#References|[5]]]</sup></div></td></tr>
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Ryan.whelan
https://microbewiki.kenyon.edu/index.php?title=Neoehrlichia_mikurensis&diff=86345&oldid=prev
Ryan.whelan at 02:06, 2 May 2013
2013-05-02T02:06:58Z
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://dx.doi.org/10.3201/eid1709.101058 6.] Andersson M, Råberg L. Wild rodents and novel human pathogen Candidatus Neoehrlichia mikurensis, southern Sweden. Emerg Infect Dis. 2011 Sep [2013 April 22]. http://dx.doi.org/10.3201/eid1709.101058</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://dx.doi.org/10.3201/eid1709.101058 6.] Andersson M, Råberg L. Wild rodents and novel human pathogen Candidatus Neoehrlichia mikurensis, southern Sweden. Emerg Infect Dis. 2011 Sep [2013 April 22]. http://dx.doi.org/10.3201/eid1709.101058</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://www.ncbi.nlm.nih.gov/pubmed/23115262 7.] FP, Maurer et al. Close geographic association of human neoehrlichiosis and tick populations carrying "Candidatus Neoehrlichia mikurensis" in eastern Switzerland. doi: 10.1128/JCM.01955-12. Epub 2012 Oct 31. http://www.ncbi.nlm.nih.gov/pubmed/23115262 </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://www.ncbi.nlm.nih.gov/pubmed/23115262 7.] FP, Maurer et al. Close geographic association of human neoehrlichiosis and tick populations carrying "Candidatus Neoehrlichia mikurensis" in eastern Switzerland. doi: 10.1128/JCM.01955-12. Epub 2012 Oct 31. http://www.ncbi.nlm.nih.gov/pubmed/23115262 </div></td></tr>
</table>
Ryan.whelan
https://microbewiki.kenyon.edu/index.php?title=Neoehrlichia_mikurensis&diff=86344&oldid=prev
Ryan.whelan at 02:06, 2 May 2013
2013-05-02T02:06:27Z
<p></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>The 16S rRNA and groEL genes have been used to identify this species on numerous occasion. <sup>[[#References|[6]]]</sup> The 16S gene is 1,426 bp in length and the groEL gene is 1,233 bp in length. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>The 16S rRNA and groEL genes have been used to identify this species on numerous occasion. <sup>[[#References|[6]]]</sup> The 16S gene is 1,426 bp in length and the groEL gene is 1,233 bp in length. </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">“Phylogram of ‘<I>Candidatus</I> Neoehrlichia mikurensis' strains TK4456R and IS58 and other members of the family Anaplasmataceae, based on 16S rRNA gene sequence comparison. GenBank accession numbers are shown in parentheses. Numbers above internal nodes indicate the percentage of 1000 bootstrap replicates that supported the branch.”</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Metabolism==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Metabolism==</div></td></tr>
</table>
Ryan.whelan
https://microbewiki.kenyon.edu/index.php?title=Neoehrlichia_mikurensis&diff=84778&oldid=prev
Ryan.whelan at 18:02, 25 April 2013
2013-04-25T18:02:12Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><I>Candidatus</I> Neoehrlichia mikurensis </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><I>Candidatus</I> Neoehrlichia mikurensis </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Previously known as ''Candidatus'' Ehrlichia walkerii <sup>[[#References|[<del style="font-weight: bold; text-decoration: none;">10</del>]]]</sup></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Previously known as ''Candidatus'' Ehrlichia walkerii <sup>[[#References|[<ins style="font-weight: bold; text-decoration: none;">9</ins>]]]</sup></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====A note on the conventional use of "Candidatus"====</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>====A note on the conventional use of "Candidatus"====</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Generally, the Candidatus designation is italicized and the genus/species is in plain Roman type such that, "''Candidatus'' Genus species". Candidatus can be abbreviated ''Ca.'' such that "''Ca.'' G. species".<sup>[[#References|[<del style="font-weight: bold; text-decoration: none;">9</del>]]]</sup></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Generally, the Candidatus designation is italicized and the genus/species is in plain Roman type such that, "''Candidatus'' Genus species". Candidatus can be abbreviated ''Ca.'' such that "''Ca.'' G. species".<sup>[[#References|[<ins style="font-weight: bold; text-decoration: none;">8</ins>]]]</sup></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Description and significance==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Description and significance==</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Pathology==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Pathology==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Until recently the infection caused by <I>Ca.</I> N. mikurensis was unnamed, but after a slew of infections involving humans were diagnosed in 2010, the infection was dubbed “neoehrlichiosis” <sup>[[#References|[<del style="font-weight: bold; text-decoration: none;">8</del>]]]</sup>. In most reported cases of neoehrlichiosis there persists a high and intermittent fever, with some ranging above 39˚C (102.2˚F). Other common symptoms in infections include anemia, unconsciousness and deep vein thrombosis. <sup>[[#References|[4]]]</sup> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Until recently the infection caused by <I>Ca.</I> N. mikurensis was unnamed, but after a slew of infections involving humans were diagnosed in 2010, the infection was dubbed “neoehrlichiosis” <sup>[[#References|[<ins style="font-weight: bold; text-decoration: none;">7</ins>]]]</sup>. In most reported cases of neoehrlichiosis there persists a high and intermittent fever, with some ranging above 39˚C (102.2˚F). Other common symptoms in infections include anemia, unconsciousness and deep vein thrombosis. <sup>[[#References|[4]]]</sup> </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>In one case from 2007, a 69 year old German man who had been suffering from an unknown illness for several months was diagnosed with what would come to be known as neoehrlichiosis. Symptoms included daily high fever (up to 39˚C), night sweats, a non-productive cough, hypochromic anemia, and occasional bouts of diarrhea. Blood and bone marrow analysis revealed the presence of <I>Ca.</I> N. mikurensis and a course of doxycycline was administered for three weeks. All symptoms alleviated quickly and within one month the patient tested negative for the presence of <I>Ca.</I> N. mikurensis. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>In one case from 2007, a 69 year old German man who had been suffering from an unknown illness for several months was diagnosed with what would come to be known as neoehrlichiosis. Symptoms included daily high fever (up to 39˚C), night sweats, a non-productive cough, hypochromic anemia, and occasional bouts of diarrhea. Blood and bone marrow analysis revealed the presence of <I>Ca.</I> N. mikurensis and a course of doxycycline was administered for three weeks. All symptoms alleviated quickly and within one month the patient tested negative for the presence of <I>Ca.</I> N. mikurensis. </div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==References==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==References==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>1. Kawahara, M., Rikihisa, Y., Isogai, E., Takahashi, M., Misumi, H., Suto, C., Shibata, S., Zhang, C., and Tsuji, M. "Ultrastructure and phylogenic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks." Int. J. Syst. Evol. Microbiol. (2004) 54:1837-1843. Published online 13 April 2004: DOI 10.1099/ijs.0.63260-0 http://ijs.sgmjournals.org/content/54/5/1837.long </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[http://ijs.sgmjournals.org/content/54/5/1837.long </ins>1.<ins style="font-weight: bold; text-decoration: none;">] </ins>Kawahara, M., Rikihisa, Y., Isogai, E., Takahashi, M., Misumi, H., Suto, C., Shibata, S., Zhang, C., and Tsuji, M. "Ultrastructure and phylogenic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks." Int. J. Syst. Evol. Microbiol. (2004) 54:1837-1843. Published online 13 April 2004: DOI 10.1099/ijs.0.63260-0 http://ijs.sgmjournals.org/content/54/5/1837.long </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>2. von Loewenich, F.D., Geibdorfer, W., Disque’, C., Matten, J., Schett, G., Sakka, S.G., and Bogdan, C. “Detection of ‘Candidatus Neoehrlichia mukurensis’ in Two Patients with Severe Febrile Illnesses: Evidence for a European Sequence Variant” J. Clin. Microbiol. July 2010 vol. 48 no. 7 2630-2635. http://jcm.asm.org/content/48/7/2630.full </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[http://jcm.asm.org/content/48/7/2630.full </ins>2.<ins style="font-weight: bold; text-decoration: none;">] </ins>von Loewenich, F.D., Geibdorfer, W., Disque’, C., Matten, J., Schett, G., Sakka, S.G., and Bogdan, C. “Detection of ‘Candidatus Neoehrlichia mukurensis’ in Two Patients with Severe Febrile Illnesses: Evidence for a European Sequence Variant” J. Clin. Microbiol. July 2010 vol. 48 no. 7 2630-2635. http://jcm.asm.org/content/48/7/2630.full </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>3. "New Tick Disease In Switzerland." Medical News Today. MediLexicon, Intl., 2 Nov. 2012. Web. 23 Jan. 2013. http://www.medicalnewstoday.com/releases/252280.php </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[http://www.medicalnewstoday.com/releases/252280.php </ins>3.<ins style="font-weight: bold; text-decoration: none;">] </ins>"New Tick Disease In Switzerland." Medical News Today. MediLexicon, Intl., 2 Nov. 2012. Web. 23 Jan. 2013. http://www.medicalnewstoday.com/releases/252280.php </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>4. Welinder-Olsson, C., Kjellin, E., Vaht, K., Jacobsson, S., and Wenneras, C. “First Case of Human ‘Candidatus Neoehrlichia mukurensis’ Infection in a Febrile Patient with Chronic Lymphocytic Leukemia”. J. Clin. Microbiol. May 2010 vol. 48 no. 5 1956-1959. http://jcm.asm.org/content/48/5/1956.full </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[http://jcm.asm.org/content/48/5/1956.full </ins>4.<ins style="font-weight: bold; text-decoration: none;">] </ins>Welinder-Olsson, C., Kjellin, E., Vaht, K., Jacobsson, S., and Wenneras, C. “First Case of Human ‘Candidatus Neoehrlichia mukurensis’ Infection in a Febrile Patient with Chronic Lymphocytic Leukemia”. J. Clin. Microbiol. May 2010 vol. 48 no. 5 1956-1959. http://jcm.asm.org/content/48/5/1956.full </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>5. Richter, Dania. Matuschka, Franz-Rainer. “’Candidatus Neoehrlichia mikurensis,’ Anaplasma phagocytophilium, and Lyme Disease Spirochetes in Question European Vector Ticks and in Feeding Ticks Removed from People”. J. Clin. Microbiol. March 2012 col. 50 no. 3. http://jcm.asm.org/content/50/3/943.full </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[http://jcm.asm.org/content/50/3/943.full </ins>5.<ins style="font-weight: bold; text-decoration: none;">] </ins>Richter, Dania. Matuschka, Franz-Rainer. “’Candidatus Neoehrlichia mikurensis,’ Anaplasma phagocytophilium, and Lyme Disease Spirochetes in Question European Vector Ticks and in Feeding Ticks Removed from People”. J. Clin. Microbiol. March 2012 col. 50 no. 3. http://jcm.asm.org/content/50/3/943.full </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>6. Andersson M, Råberg L. Wild rodents and novel human pathogen Candidatus Neoehrlichia mikurensis, southern Sweden. Emerg Infect Dis. 2011 Sep [2013 April 22]. http://dx.doi.org/10.3201/eid1709.101058</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[http://dx.doi.org/10.3201/eid1709.101058 </ins>6.<ins style="font-weight: bold; text-decoration: none;">] </ins>Andersson M, Råberg L. Wild rodents and novel human pathogen Candidatus Neoehrlichia mikurensis, southern Sweden. Emerg Infect Dis. 2011 Sep [2013 April 22]. http://dx.doi.org/10.3201/eid1709.101058</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Pictures: 7. Kawahara, Makoto et al. Ultrastructure and phylogenetic analysis of ‘Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks. doi: 10.1099/ijs.0.63260-0 IJSEM September 2004 vol. 54 no. 5 1837-1843. http://ijs.sgmjournals.org/content/54/5/1837.full </del></div></td><td colspan="2" class="diff-side-added"></td></tr>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">8</del>. FP, Maurer et al. Close geographic association of human neoehrlichiosis and tick populations carrying "Candidatus Neoehrlichia mikurensis" in eastern Switzerland. doi: 10.1128/JCM.01955-12. Epub 2012 Oct 31. http://www.ncbi.nlm.nih.gov/pubmed/23115262 </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[http://www</ins>.<ins style="font-weight: bold; text-decoration: none;">ncbi.nlm.nih.gov/pubmed/23115262 7.] </ins>FP, Maurer et al. Close geographic association of human neoehrlichiosis and tick populations carrying "Candidatus Neoehrlichia mikurensis" in eastern Switzerland. doi: 10.1128/JCM.01955-12. Epub 2012 Oct 31. http://www.ncbi.nlm.nih.gov/pubmed/23115262 </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">9</del>. Firrao, G. ‘Candidatus Phytoplasma’, a taxon for the wall-less, non-helical prokaryotes that colonize plant phloem and insects. doi: 10.1099/ijs.0.02854-0 IJSEM July 2004 vol. 54 no. 4 1243-1255. http://ijs.sgmjournals.org/content/54/4/1243</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[http://ijs</ins>.<ins style="font-weight: bold; text-decoration: none;">sgmjournals.org/content/54/4/1243 8.] </ins>Firrao, G. ‘Candidatus Phytoplasma’, a taxon for the wall-less, non-helical prokaryotes that colonize plant phloem and insects. doi: 10.1099/ijs.0.02854-0 IJSEM July 2004 vol. 54 no. 4 1243-1255. http://ijs.sgmjournals.org/content/54/4/1243</div></td></tr>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">10</del>. Jahfari S, Fonville M, Hengeveld P, Reusken C, Scholte EJ, Takken W, Heyman P, Medlock J, Heylen D, Kleve J, et al.: Prevalence of neoehrlichia mikurensis in ticks and rodents from north-west Europe. Parasite Vectors 2012, 5(1):74. http://www.parasitesandvectors.com/content/5/1/74#B9</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[http://www</ins>.<ins style="font-weight: bold; text-decoration: none;">parasitesandvectors.com/content/5/1/74#B9 9.] </ins>Jahfari S, Fonville M, Hengeveld P, Reusken C, Scholte EJ, Takken W, Heyman P, Medlock J, Heylen D, Kleve J, et al.: Prevalence of neoehrlichia mikurensis in ticks and rodents from north-west Europe. Parasite Vectors 2012, 5(1):74. http://www.parasitesandvectors.com/content/5/1/74#B9</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Edited by Ryan Whelan, student of Dr. Lisa R. Moore, University of Southern Maine, Department of Biological Sciences, http://www.usm.maine.edu/bio</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Edited by Ryan Whelan, student of Dr. Lisa R. Moore, University of Southern Maine, Department of Biological Sciences, http://www.usm.maine.edu/bio</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Category: Uncurated Pages</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Category: Uncurated Pages</div></td></tr>
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Ryan.whelan
https://microbewiki.kenyon.edu/index.php?title=Neoehrlichia_mikurensis&diff=84775&oldid=prev
Ryan.whelan at 17:56, 25 April 2013
2013-04-25T17:56:06Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 17:56, 25 April 2013</td>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Previously known as ''Candidatus'' Ehrlichia walkerii<sup>[[#References|[10]]]</sup></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Previously known as ''Candidatus'' Ehrlichia walkerii <sup>[[#References|[10]]]</sup></div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Generally, the Candidatus designation is italicized and the genus/species is in plain Roman type such that, "''Candidatus'' Genus species". Candidatus can be abbreviated ''Ca.'' such that "''Ca.'' G. species".<sup>[[#References|[9]]]</sup></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Generally, the Candidatus designation is italicized and the genus/species is in plain Roman type such that, "''Candidatus'' Genus species". Candidatus can be abbreviated ''Ca.'' such that "''Ca.'' G. species".<sup>[[#References|[9]]]</sup></div></td></tr>
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Ryan.whelan