Reoviridae: Difference between revisions

From MicrobeWiki, the student-edited microbiology resource
No edit summary
No edit summary
Line 7: Line 7:
===Genera===
===Genera===


''[[Orthoreovirus]], Orbivirus, [[Rotavirus]], Coltivirus, Aquareovirus, Seadornavirus, Cypovirus, Idnoreovirus, Fijivirus, Phytoreovirus, Oryzavirus, Mycoreovirus''
''[[Orthoreovirus]], [[Rotavirus]], Orbivirus, Coltivirus, Aquareovirus, Seadornavirus, Cypovirus, Idnoreovirus, Fijivirus, Phytoreovirus, Oryzavirus, Mycoreovirus''


==Description and Significance==
==Description and Significance==
Line 15: Line 15:
==Genome Structure==
==Genome Structure==


The reovirus genome is monomeric,  
The reovirus genome is monomeric and consist of ten to twelve segments (depending on the genus) of linear, double-stranded RNA.  The complete genome is 18200-30500 nucleotides long.  There is a methylated nucleotide cap on the 5'-terminus.  Each virion contains a full-length copy of the genome.  (source: [http://phene.cpmc.columbia.edu/ICTVdB/00.060.htm ICTVdB])


==Virion Structure of a Reovirus==
==Virion Structure of a Reovirus==


 
Reovirus virions are non-enveloped and consist of a capsid, a core, and a nucleoprotein complex.  The capsid is 60-80nm in diameter and  is icosahedral.  The virion has a double protein shell.  Virus particles can be in inclusion bodies that are not occluded and contain one nucleocapsid, or they can be occluded by protein bodies. 


==Reproduction Cycle of a Reovirus in a Host Cell==
==Reproduction Cycle of a Reovirus in a Host Cell==

Revision as of 16:07, 19 June 2006

Baltimore Classification

Higher order taxa

Viruses; dsRNA viruses; Reoviridae

Genera

Orthoreovirus, Rotavirus, Orbivirus, Coltivirus, Aquareovirus, Seadornavirus, Cypovirus, Idnoreovirus, Fijivirus, Phytoreovirus, Oryzavirus, Mycoreovirus

Description and Significance

Reoviruses, or Respiratory Enteric Orphan viruses, infect invertebrates, vertebrates, and plants. In vertebrates, reoviruses cause infections of the respiratory and gastrointestinal tracts. Rotaviruses, part of the Reovirus family, are a major cause of infant deaths in the developing world, killing over 800,000 children under the age of 2 each year. Originally, reoviruses were classified as echoviruses, in the family Picornaviridae. (sources: Microbiology @ Leicester, Wong)

Genome Structure

The reovirus genome is monomeric and consist of ten to twelve segments (depending on the genus) of linear, double-stranded RNA. The complete genome is 18200-30500 nucleotides long. There is a methylated nucleotide cap on the 5'-terminus. Each virion contains a full-length copy of the genome. (source: ICTVdB)

Virion Structure of a Reovirus

Reovirus virions are non-enveloped and consist of a capsid, a core, and a nucleoprotein complex. The capsid is 60-80nm in diameter and is icosahedral. The virion has a double protein shell. Virus particles can be in inclusion bodies that are not occluded and contain one nucleocapsid, or they can be occluded by protein bodies.

Reproduction Cycle of a Reovirus in a Host Cell

Viral Ecology & Pathology

References

ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/

Microbiology @ Leicester: Virology: Reoviruses

Wong, Catherine. Reoviridae 2004.