Difference between revisions of "Rickettsia prowazekii"

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Describe the size and content of the genome.  How many chromosomes?  Circular or linear?  Other interesting features?  What is known about its sequence?
 
Describe the size and content of the genome.  How many chromosomes?  Circular or linear?  Other interesting features?  What is known about its sequence?
 
Does it have any plasmids?  Are they important to the organism's lifestyle?
 
Does it have any plasmids?  Are they important to the organism's lifestyle?
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 +
The ''R. prowazekii'' genome is circular, containing 1,111,523 base pairs and 834 protein coding genes.  Also, 24% of ''R. prowazekii'' DNA is non-coding- the largest amount in any microbial genome.  No genes code for anaerobic glycolosis, however, complete coding sequences for the tricarboxylicacid (TCA) cycle and respiratory-chain complex are found indicating ''R. prowazekii'' is the closest microbial ancestor to mitochrondia.
  
 
==Cell structure and metabolism==
 
==Cell structure and metabolism==

Revision as of 06:00, 27 April 2007

A Microbial Biorealm page on the genus Rickettsia prowazekii

Classification

Higher order taxa

Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Rickettsiaceae

Species

NCBI: Taxonomy

Rickettsia prowazekii

Description and significance

Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. Include a picture or two (with sources) if you can find them.

Genome structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?

The R. prowazekii genome is circular, containing 1,111,523 base pairs and 834 protein coding genes. Also, 24% of R. prowazekii DNA is non-coding- the largest amount in any microbial genome. No genes code for anaerobic glycolosis, however, complete coding sequences for the tricarboxylicacid (TCA) cycle and respiratory-chain complex are found indicating R. prowazekii is the closest microbial ancestor to mitochrondia.

Cell structure and metabolism

Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

Enter summaries of the most recent research here--at least three required

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Edited by Matthew Noble, student of Rachel Larsen