Rinderpest: Difference between revisions
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The Rinderpest virion is characterized by a semispherical-pleomorphic capsid surrounded by an envelope of host-derived lipids (ICTV Db, 2006). Enveloped capsids range from 150-250 nm in diameter, depending on the individual virus and the technique used. Projections of glycoproteins through channels in the lipous envelope are roughly 9-15 nm in length (ICTV Db, 2006). | |||
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Revision as of 11:16, 19 September 2008
A Viral Biorealm page on the family Rinderpest
Baltimore Classification
Group V: (-) sense single-stranded RNA viruses
Higher order categories
Order: Mononegavirales
Family: Dicistroviridae
Genus: Cripavirus
Description and Significance
Rinderpest Virus (RPV), a term derived from German, meaning cattle-plague, is the cause of gastrointestinal illness most commonly seen in cattle and buffalo, but occurs less frequently and with less conspicuity in sheep, goats, camels, and some species of Sus. Among livestock plagues, Rinderpest is one of the oldest on record, dating back 9000 years, and was the subject of several pioneering insights in agricultural medicine (Broad, 1983). It is also believed that all other members of the Morbillivirus genus evolved from RPV (Norrby, E; 1985). The virus has recently been made to recombine to aid in the production of a more effective vaccine (Baron, Foster-Cuevas, et al.1999). RPV cannot infect humans, but the high mortality rate it exhibits in immunologically-naïve populations of cornerstone livestock, it is devastating to international trade, rural incomes, and the survivability of local populations alike (Shaila, 2006).
Genome Structure
The RPV genome is 15,881 base pairs long, and consists of a single molecule (nonsegmented) of negative-sense single-stranded RNA. This contains six genes that code for structural proteins, and two that code for non-structural proteins (Shaila, 2006) that are transcribed in order form a single promoter and the 3’ terminus of the molecule (Baron; Barrett;1999).
Virion Structure of a Rinderpest virus
The Rinderpest virion is characterized by a semispherical-pleomorphic capsid surrounded by an envelope of host-derived lipids (ICTV Db, 2006). Enveloped capsids range from 150-250 nm in diameter, depending on the individual virus and the technique used. Projections of glycoproteins through channels in the lipous envelope are roughly 9-15 nm in length (ICTV Db, 2006).
Reproductive Cycle of a ______virus in a Host Cell
Viral Ecology & Pathology
References
Example:
Page authored for BIOL 375 Virology, September 2008
