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Salmonella Typhimurium BRD509 - Revision history
2024-03-29T01:40:06Z
Revision history for this page on the wiki
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https://microbewiki.kenyon.edu/index.php?title=Salmonella_Typhimurium_BRD509&diff=91838&oldid=prev
Mcca0590: /* Genus Species */
2013-07-28T23:06:09Z
<p><span dir="auto"><span class="autocomment">Genus Species</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 23:06, 28 July 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>cellular organisms; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae [[#References | [10]]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>cellular organisms; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae [[#References | [10]]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>==='''''<del style="font-weight: bold; text-decoration: none;">Genus Species</del>'''''===</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>==='''''<ins style="font-weight: bold; text-decoration: none;">Salmonella enterica</ins>'''''===</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">'''''Salmonella enterica'''''; </del>subsp. enterica serovar Typhimurium, strain BRD509 [[#References | [10]]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>subsp. enterica serovar Typhimurium, strain BRD509 [[#References | [10]]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File: salmonella.jpg|thumb|right|Colonies of pathogenic bacteria growing on an agar culture plate - Salmonella enterica (serovar typhimurium)]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File: salmonella.jpg|thumb|right|Colonies of pathogenic bacteria growing on an agar culture plate - Salmonella enterica (serovar typhimurium)]]</div></td></tr>
</table>
Mcca0590
https://microbewiki.kenyon.edu/index.php?title=Salmonella_Typhimurium_BRD509&diff=91837&oldid=prev
Mcca0590: /* Ecology and Pathogenesis */
2013-07-28T23:02:02Z
<p><span dir="auto"><span class="autocomment">Ecology and Pathogenesis</span></span></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Ecology and Pathogenesis==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Ecology and Pathogenesis==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Salmonella Typhimurium, much like all other species of the genus Salmonella, naturally live within the gastrointestinal system of both animals and humans. More specifically Salmonella thrives within the intestinal tract as it is not made to withstand the high acidity of the stomach. </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">''</ins>Salmonella Typhimurium<ins style="font-weight: bold; text-decoration: none;">''</ins>, much like all other species of the genus <ins style="font-weight: bold; text-decoration: none;">''</ins>Salmonella<ins style="font-weight: bold; text-decoration: none;">''</ins>, naturally live within the gastrointestinal system of both animals and humans. More specifically <ins style="font-weight: bold; text-decoration: none;">''</ins>Salmonella<ins style="font-weight: bold; text-decoration: none;">'' </ins>thrives within the intestinal tract as it is not made to withstand the high acidity of the stomach. </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>The pathogenesis of ''Salmonella'' begins when contact with contaminated food or water occurs. Contamination occurs through contact of fecal matter with the food or water source and can occur through a lack of proper hygiene or it is also possible for insects, primarily flys, to play a role in contamination as they move from fecal matter to a food source.[8] After entering into the host and passing into the intestinal tract the bacteria will colonize the intestines, and then enter dendritic cells, enterocytes and M cells (microfold cells) along the intestinal epithelium. This process of entering into the host cells makes use of a series of a type III secretion system (T3SS1 as well as having many PAMPS (pathogen associated molecular patterns) the the host cell will detect and attempt to phagocytosis the ''Salmonella''. However, the ''Salmonella'' creates a barrier preventing it from being destroyed called the salmonella containing vacuole. In this protected state the ''Salmonella'' will eventually be carried to lymph tissues such as the lymph nodes or the spleen, these are sites that ''Salmonella'' will gather. Some of the other virulence factors that play a role in pathogenesis is another type III secretion system (T3SS2) which plays a role in virulence as well as survival within macrophages, two genes on a virulence plasmid spvB and spvC both of which play unique roles in hindering the host defenses, superoxide dismutase which protects ''Salmonella'' by neutralizing reactive oxygen species that are produced by the host and a variety of ion acquisition proteins that collect required ions for cellular replication and bring them back to the bacterai. [9] After infection occurs a patient suffering salmonellosis (infection with ''Salmonella'') would experience gastroenteritis the symptoms of which generally include nausea, vomiting, diarrhea that will sometimes include with blood and mucus, and slight fever. The salmonellosis will generally pass within a few days, after which the individual may obtain some degree of immunity, in infants less then one year old bloodstream infection (sepsis) is common and thus antibiotic treatment is recommended. If extreme cases of diarrhea and vomiting are experienced it might be necessary for someone suffering salmonellosis to enter the hospital to receive IV liquids to prevent dehydration from reaching a dangerous level. [8]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>The pathogenesis of ''Salmonella'' begins when contact with contaminated food or water occurs. Contamination occurs through contact of fecal matter with the food or water source and can occur through a lack of proper hygiene or it is also possible for insects, primarily flys, to play a role in contamination as they move from fecal matter to a food source. <ins style="font-weight: bold; text-decoration: none;">[[#References | </ins>[8<ins style="font-weight: bold; text-decoration: none;">]]</ins>] After entering into the host and passing into the intestinal tract the bacteria will colonize the intestines, and then enter dendritic cells, enterocytes and M cells (microfold cells) along the intestinal epithelium. This process of entering into the host cells makes use of a series of a type III secretion system (T3SS1 as well as having many PAMPS (pathogen associated molecular patterns) the the host cell will detect and attempt to phagocytosis the ''Salmonella''. However, the ''Salmonella'' creates a barrier preventing it from being destroyed called the salmonella containing vacuole. In this protected state the ''Salmonella'' will eventually be carried to lymph tissues such as the lymph nodes or the spleen, these are sites that ''Salmonella'' will gather. Some of the other virulence factors that play a role in pathogenesis is another type III secretion system (T3SS2) which plays a role in virulence as well as survival within macrophages, two genes on a virulence plasmid spvB and spvC both of which play unique roles in hindering the host defenses, superoxide dismutase which protects ''Salmonella'' by neutralizing reactive oxygen species that are produced by the host and a variety of ion acquisition proteins that collect required ions for cellular replication and bring them back to the bacterai. <ins style="font-weight: bold; text-decoration: none;"> [[#References | </ins>[9<ins style="font-weight: bold; text-decoration: none;">]]</ins>] After infection occurs a patient suffering salmonellosis (infection with ''Salmonella'') would experience gastroenteritis the symptoms of which generally include nausea, vomiting, diarrhea that will sometimes include with blood and mucus, and slight fever. The salmonellosis will generally pass within a few days, after which the individual may obtain some degree of immunity, in infants less then one year old bloodstream infection (sepsis) is common and thus antibiotic treatment is recommended. If extreme cases of diarrhea and vomiting are experienced it might be necessary for someone suffering salmonellosis to enter the hospital to receive IV liquids to prevent dehydration from reaching a dangerous level. <ins style="font-weight: bold; text-decoration: none;"> [[#References | </ins>[8<ins style="font-weight: bold; text-decoration: none;">]]</ins>]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==References==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==References==</div></td></tr>
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Mcca0590
https://microbewiki.kenyon.edu/index.php?title=Salmonella_Typhimurium_BRD509&diff=91836&oldid=prev
Mcca0590: /* Structure, Metabolism, and Life Cycle */
2013-07-28T22:59:23Z
<p><span dir="auto"><span class="autocomment">Structure, Metabolism, and Life Cycle</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 22:59, 28 July 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Structure, Metabolism, and Life Cycle==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Structure, Metabolism, and Life Cycle==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>One of the most interesting and important things about the BRD509 strain of ''Salmonella Typhimurium'' is the knockout of two of its genes, specifically the aroA and the aroD genes. [2] The knockout of these two genes plays a crucial role in attenuating the bacteria as this strain grows much more slowly due to the loss of the ability to synthesize essential metabolites. [2] <del style="font-weight: bold; text-decoration: none;"> </del>The aroA gene and aroD genes are responsible for the creation of the enzymes 3-phosphoshikimate 1-carboxyvinyltransferase [3] and 3-dehydroquinate dehydratase [4], respectively, these two enzymes play a role in the creation of aromatic amino acids phenylalanine, tyrosine and tryptophan [5][6]. It is this slowed rate of growth due to these missing amino acids that allows the hosts immune system to better handle the challenge of the Salmonella. Within the host ''Salmonella'' will make use of use glucose that it can find within the hosts body. The replication processes of ''Salmonella Typhimurium'' are very typical of most bacteria, undergoing fission, however, the location that this occurs is unique to ''Salmonella'' in that it will insert itself into host cells within a salmonella containing vacuole (SCV), in doing this it creates an environment for itself that will provide it will many of the needed nutrients for replication. [7] All species of ''Salmonella'' follow the same life cycle in which cells will be passed through the intestines with fecal matter and will leave the host organism when defection occurs. The ''Salmonella'' then must be transferred to a new host, through ingestion of the bacteria, which most often occurs from eating contaminated foods or water, the bacteria will then pass through the stomach into the intestinal tract where it will begin colonization.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>One of the most interesting and important things about the BRD509 strain of ''Salmonella Typhimurium'' is the knockout of two of its genes, specifically the aroA and the aroD genes. <ins style="font-weight: bold; text-decoration: none;"> [[#References | </ins>[2<ins style="font-weight: bold; text-decoration: none;">]]</ins>] The knockout of these two genes plays a crucial role in attenuating the bacteria as this strain grows much more slowly due to the loss of the ability to synthesize essential metabolites. <ins style="font-weight: bold; text-decoration: none;"> [[#References | </ins>[2]<ins style="font-weight: bold; text-decoration: none;">]] </ins>The aroA gene and aroD genes are responsible for the creation of the enzymes 3-phosphoshikimate 1-carboxyvinyltransferase <ins style="font-weight: bold; text-decoration: none;"> [[#References | </ins>[3<ins style="font-weight: bold; text-decoration: none;">]]</ins>] and 3-dehydroquinate dehydratase <ins style="font-weight: bold; text-decoration: none;"> [[#References | </ins>[4<ins style="font-weight: bold; text-decoration: none;">]]</ins>], respectively, these two enzymes play a role in the creation of aromatic amino acids phenylalanine, tyrosine and tryptophan <ins style="font-weight: bold; text-decoration: none;"> [[#References | </ins>[5<ins style="font-weight: bold; text-decoration: none;">]]</ins>] <ins style="font-weight: bold; text-decoration: none;">[[#References | </ins>[6<ins style="font-weight: bold; text-decoration: none;">]]</ins>]. It is this slowed rate of growth due to these missing amino acids that allows the hosts immune system to better handle the challenge of the Salmonella. Within the host ''Salmonella'' will make use of use glucose that it can find within the hosts body. The replication processes of ''Salmonella Typhimurium'' are very typical of most bacteria, undergoing fission, however, the location that this occurs is unique to ''Salmonella'' in that it will insert itself into host cells within a salmonella containing vacuole (SCV), in doing this it creates an environment for itself that will provide it will many of the needed nutrients for replication. <ins style="font-weight: bold; text-decoration: none;"> [[#References | </ins>[7<ins style="font-weight: bold; text-decoration: none;">]]</ins>] All species of ''Salmonella'' follow the same life cycle in which cells will be passed through the intestines with fecal matter and will leave the host organism when defection occurs. The ''Salmonella'' then must be transferred to a new host, through ingestion of the bacteria, which most often occurs from eating contaminated foods or water, the bacteria will then pass through the stomach into the intestinal tract where it will begin colonization.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Ecology and Pathogenesis==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Ecology and Pathogenesis==</div></td></tr>
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Mcca0590
https://microbewiki.kenyon.edu/index.php?title=Salmonella_Typhimurium_BRD509&diff=91835&oldid=prev
Mcca0590: /* Description and Significance */
2013-07-28T22:57:27Z
<p><span dir="auto"><span class="autocomment">Description and Significance</span></span></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Description and Significance==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Description and Significance==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>''Salmonella Typhimurium'', along with all bacteria of the genus ''Salmonella'', are gram-negative, rod-shaped (bacillus), and facultatively anaerobic bacteria within the family ''Enterobacteriaceae''. ''Salmonella'' are also glucose fermentors as when they are grown on a TSI agar slant it is possible to see that they undergo glucose fermentation and will produce H2S as well as other gases, in addition the TSI slants shows that they are not lactose or sucrose fermentors. [1] ''Salmonella Typhimurium'' is an important subspecies of ''Salmonella'' as when it is used within a mouse model the pathogenesis and symptoms of infection mimic those of a human infection with ''Salmonella Typhi'' (the causative agent of typhoid fever). Using a mouse model of ''Salmonella Typhimurium'' allows researchers to look for antigens that are conserved across various subspecies and look for antigens that could possibly be vaccine candidates. The strain BRD509 is of great importance in the mouse model and also in this search for possible vaccine candidates as it is an attenuated strain that retains many of the antigenic components that trigger an adaptive immune response allowing for infection to occur without killing the host. This allows for further procedures such as a challenge with a virulent strain of ''Salmonella'', sacrificing infected mice at specific time points and viewing the cell populations using flow cytometry based analysis these methods along with others will further elucidate the pathogenesis and possible vaccine candidates.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>''Salmonella Typhimurium'', along with all bacteria of the genus ''Salmonella'', are gram-negative, rod-shaped (bacillus), and facultatively anaerobic bacteria within the family ''Enterobacteriaceae''. ''Salmonella'' are also glucose fermentors as when they are grown on a TSI agar slant it is possible to see that they undergo glucose fermentation and will produce H2S as well as other gases, in addition the TSI slants shows that they are not lactose or sucrose fermentors. <ins style="font-weight: bold; text-decoration: none;"> [[#References | </ins>[1<ins style="font-weight: bold; text-decoration: none;">]]</ins>] ''Salmonella Typhimurium'' is an important subspecies of ''Salmonella'' as when it is used within a mouse model the pathogenesis and symptoms of infection mimic those of a human infection with ''Salmonella Typhi'' (the causative agent of typhoid fever). Using a mouse model of ''Salmonella Typhimurium'' allows researchers to look for antigens that are conserved across various subspecies and look for antigens that could possibly be vaccine candidates. The strain BRD509 is of great importance in the mouse model and also in this search for possible vaccine candidates as it is an attenuated strain that retains many of the antigenic components that trigger an adaptive immune response allowing for infection to occur without killing the host. This allows for further procedures such as a challenge with a virulent strain of ''Salmonella'', sacrificing infected mice at specific time points and viewing the cell populations using flow cytometry based analysis these methods along with others will further elucidate the pathogenesis and possible vaccine candidates.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Structure, Metabolism, and Life Cycle==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Structure, Metabolism, and Life Cycle==</div></td></tr>
</table>
Mcca0590
https://microbewiki.kenyon.edu/index.php?title=Salmonella_Typhimurium_BRD509&diff=91834&oldid=prev
Mcca0590: /* Classification */
2013-07-28T22:56:44Z
<p><span dir="auto"><span class="autocomment">Classification</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 22:56, 28 July 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Classification==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Classification==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>cellular organisms; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae [10]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>cellular organisms; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae <ins style="font-weight: bold; text-decoration: none;"> [[#References | </ins>[10<ins style="font-weight: bold; text-decoration: none;">]]</ins>]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==='''''Genus Species'''''===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==='''''Genus Species'''''===</div></td></tr>
</table>
Mcca0590
https://microbewiki.kenyon.edu/index.php?title=Salmonella_Typhimurium_BRD509&diff=91833&oldid=prev
Mcca0590: /* Genus Species */
2013-07-28T22:55:52Z
<p><span dir="auto"><span class="autocomment">Genus Species</span></span></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==='''''Genus Species'''''===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==='''''Genus Species'''''===</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''''Salmonella enterica'''''; subsp. enterica serovar Typhimurium, strain BRD509 [10]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''''Salmonella enterica'''''; subsp. enterica serovar Typhimurium, strain BRD509 <ins style="font-weight: bold; text-decoration: none;"> [[#References | </ins>[10<ins style="font-weight: bold; text-decoration: none;">]]</ins>]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File: salmonella.jpg|thumb|right|Colonies of pathogenic bacteria growing on an agar culture plate - Salmonella enterica (serovar typhimurium)]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File: salmonella.jpg|thumb|right|Colonies of pathogenic bacteria growing on an agar culture plate - Salmonella enterica (serovar typhimurium)]]</div></td></tr>
</table>
Mcca0590
https://microbewiki.kenyon.edu/index.php?title=Salmonella_Typhimurium_BRD509&diff=89897&oldid=prev
Mcca0590: /* References */
2013-07-22T04:21:49Z
<p><span dir="auto"><span class="autocomment">References</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 04:21, 22 July 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[7] van der Heijden J, Finlay BB. Type III Effector-Mediated Processes in Salmonella Infection. Future Microbiol. 2012;7(6):685-703.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[7] van der Heijden J, Finlay BB. Type III Effector-Mediated Processes in Salmonella Infection. Future Microbiol. 2012;7(6):685-703.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[8] salmonellosis [internet] Encyclopædia Britannica; Aug 14, 2008 [cited 2013 July 21]. Available from: http://www.britannica.com/EBchecked/topic/519555/salmonellosis</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[8] salmonellosis [internet] Encyclopædia Britannica; Aug 14, 2008 [cited 2013 July 21]. Available from: http://www.britannica.com/EBchecked/topic/519555/salmonellosis</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[9]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[9] <ins style="font-weight: bold; text-decoration: none;">Ibarra JA, Steele-Mortimer O. Salmonella – the ultimate insider. Salmonella virulence factors that modulate intracellular survival. Cell Microbiol. 2009 November; 11(11): 1579–1586.</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[10] Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 [internet] NCBI; no date listed for posting [cited 2013 July 21]. Available from: http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=216597&lvl=3&keep=1&srchmode=1&unlock&lin=f</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Author==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Author==</div></td></tr>
</table>
Mcca0590
https://microbewiki.kenyon.edu/index.php?title=Salmonella_Typhimurium_BRD509&diff=89895&oldid=prev
Mcca0590: /* Classification */
2013-07-22T04:16:16Z
<p><span dir="auto"><span class="autocomment">Classification</span></span></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Classification==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Classification==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>cellular organisms; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae [<del style="font-weight: bold; text-decoration: none;">1</del>]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>cellular organisms; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae [<ins style="font-weight: bold; text-decoration: none;">10</ins>]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==='''''Genus Species'''''===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==='''''Genus Species'''''===</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''''Salmonella enterica'''''; subsp. enterica serovar Typhimurium, strain BRD509 [<del style="font-weight: bold; text-decoration: none;">1</del>]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''''Salmonella enterica'''''; subsp. enterica serovar Typhimurium, strain BRD509 [<ins style="font-weight: bold; text-decoration: none;">10</ins>]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File: salmonella.jpg|thumb|right|Colonies of pathogenic bacteria growing on an agar culture plate - Salmonella enterica (serovar typhimurium)]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File: salmonella.jpg|thumb|right|Colonies of pathogenic bacteria growing on an agar culture plate - Salmonella enterica (serovar typhimurium)]]</div></td></tr>
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https://microbewiki.kenyon.edu/index.php?title=Salmonella_Typhimurium_BRD509&diff=89894&oldid=prev
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<p><span dir="auto"><span class="autocomment">References</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 04:15, 22 July 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[5] Wikipedia contributors. ESPS synthase [Internet]. Wikipedia, The Free Encyclopedia; 22 March 2013 at 15:46 [cited 2013 July 21]. Available from: http://en.wikipedia.org/wiki/EPSP_synthase</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[5] Wikipedia contributors. ESPS synthase [Internet]. Wikipedia, The Free Encyclopedia; 22 March 2013 at 15:46 [cited 2013 July 21]. Available from: http://en.wikipedia.org/wiki/EPSP_synthase</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[6] Wikipedia contributors. 3-dehydroquinate dehydratase [Internet]. Wikipedia, The Free Encyclopedia; 17 March 2013 at 19:52 [cited 2013 July 21]. Available from: http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[6] Wikipedia contributors. 3-dehydroquinate dehydratase [Internet]. Wikipedia, The Free Encyclopedia; 17 March 2013 at 19:52 [cited 2013 July 21]. Available from: http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[7]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[7<ins style="font-weight: bold; text-decoration: none;">] van der Heijden J, Finlay BB. Type III Effector-Mediated Processes in Salmonella Infection. Future Microbiol. 2012;7(6):685-703.</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[8] salmonellosis [internet] Encyclopædia Britannica; Aug 14, 2008 [cited 2013 July 21]. Available from: http://www.britannica.com/EBchecked/topic/519555/salmonellosis</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[9</ins>]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Author==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Author==</div></td></tr>
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Mcca0590
https://microbewiki.kenyon.edu/index.php?title=Salmonella_Typhimurium_BRD509&diff=89873&oldid=prev
Mcca0590: /* References */
2013-07-22T03:54:32Z
<p><span dir="auto"><span class="autocomment">References</span></span></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==References==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==References==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[1] <del style="font-weight: bold; text-decoration: none;">EXAMPLE ONLY</del>. <del style="font-weight: bold; text-decoration: none;">REPLACE WITH YOUR REFERENCES</del>. <del style="font-weight: bold; text-decoration: none;">Takai</del>, <del style="font-weight: bold; text-decoration: none;">K</del>.<del style="font-weight: bold; text-decoration: none;">, Sugai, A</del>., <del style="font-weight: bold; text-decoration: none;">Itoh, T</del>.<del style="font-weight: bold; text-decoration: none;">, and Horikoshi, K</del>. <del style="font-weight: bold; text-decoration: none;">2000</del>. <del style="font-weight: bold; text-decoration: none;">"''Palaeococcus ferrophilus'' gen</del>. <del style="font-weight: bold; text-decoration: none;">nov</del>., <del style="font-weight: bold; text-decoration: none;">sp</del>. <del style="font-weight: bold; text-decoration: none;">nov</del>., <del style="font-weight: bold; text-decoration: none;">a barophilic, hyperthermophilic archaeon </del>from <del style="font-weight: bold; text-decoration: none;">a deep</del>-<del style="font-weight: bold; text-decoration: none;">sea hydrothermal vent chimney"</del>. <del style="font-weight: bold; text-decoration: none;">''International Journal of Systematic and Evolutionary Microbiology''</del>. <del style="font-weight: bold; text-decoration: none;">50</del>: <del style="font-weight: bold; text-decoration: none;">489-500</del>. http://<del style="font-weight: bold; text-decoration: none;">ijs</del>.<del style="font-weight: bold; text-decoration: none;">sgmjournals</del>.org/<del style="font-weight: bold; text-decoration: none;">cgi</del>/<del style="font-weight: bold; text-decoration: none;">reprint</del>/<del style="font-weight: bold; text-decoration: none;">50</del>/<del style="font-weight: bold; text-decoration: none;">2</del>/<del style="font-weight: bold; text-decoration: none;">489</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[1] <ins style="font-weight: bold; text-decoration: none;">Wikipedia contributors</ins>. <ins style="font-weight: bold; text-decoration: none;">Salmonella [Internet]</ins>. <ins style="font-weight: bold; text-decoration: none;">Wikipedia</ins>, <ins style="font-weight: bold; text-decoration: none;">The Free Encyclopedia; July 19 2013 at 14:15 [cited 2013 July 21]. Available from:https://en</ins>.<ins style="font-weight: bold; text-decoration: none;">wikipedia</ins>.<ins style="font-weight: bold; text-decoration: none;">org/wiki/Salmonella</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[2] Griffin AJ</ins>, <ins style="font-weight: bold; text-decoration: none;">McSorley SJ</ins>. <ins style="font-weight: bold; text-decoration: none;">Generation of Salmonella-specific Th1 cells requires sustained antigen stimulation</ins>. <ins style="font-weight: bold; text-decoration: none;">Vaccine</ins>. <ins style="font-weight: bold; text-decoration: none;">2011 March 24; 29 (15): 2967 -2704</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[3]Salmonella enterica enterica serovar Typhimurium str</ins>. <ins style="font-weight: bold; text-decoration: none;">SL1344 Enzyme: 3-phosphoshikimate 1-carboxyvinyltransferase [internet]</ins>. <ins style="font-weight: bold; text-decoration: none;">Biocyc Database collection: Sun Jul 21</ins>, <ins style="font-weight: bold; text-decoration: none;">2013 [cited 2013 july 21]. Available from: http://ecocyc.org/SENT216597/NEW-IMAGE?type=NIL&object=GJB7-932&redirect=T</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[4] Salmonella enterica enterica serovar Typhimurium str</ins>. <ins style="font-weight: bold; text-decoration: none;">SL1344 Enzyme: 3-dehydroquinate dehydratase [internet]</ins>. <ins style="font-weight: bold; text-decoration: none;">Biocyc Database collection: Sun Jul 21</ins>, <ins style="font-weight: bold; text-decoration: none;">2013 [cited 2013 july 21]. Available </ins>from<ins style="font-weight: bold; text-decoration: none;">: http://ecocyc.org/SENT216597/NEW</ins>-<ins style="font-weight: bold; text-decoration: none;">IMAGE?type=NIL&object=GJB7-1314&redirect=T</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[5] Wikipedia contributors</ins>. <ins style="font-weight: bold; text-decoration: none;">ESPS synthase [Internet]</ins>. <ins style="font-weight: bold; text-decoration: none;">Wikipedia, The Free Encyclopedia; 22 March 2013 at 15</ins>:<ins style="font-weight: bold; text-decoration: none;">46 [cited 2013 July 21]</ins>. <ins style="font-weight: bold; text-decoration: none;">Available from: </ins>http://<ins style="font-weight: bold; text-decoration: none;">en</ins>.<ins style="font-weight: bold; text-decoration: none;">wikipedia</ins>.org/<ins style="font-weight: bold; text-decoration: none;">wiki</ins>/<ins style="font-weight: bold; text-decoration: none;">EPSP_synthase</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[6] Wikipedia contributors. 3-dehydroquinate dehydratase [Internet]. Wikipedia, The Free Encyclopedia; 17 March 2013 at 19:52 [cited 2013 July 21]. Available from: http:</ins>//<ins style="font-weight: bold; text-decoration: none;">en.wikipedia.org/wiki</ins>/<ins style="font-weight: bold; text-decoration: none;">3-dehydroquinate_dehydratase</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[7]</ins></div></td></tr>
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