Difference between revisions of "Shigella"

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(Pathology)
(Cell structure and metabolism)
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Interesting features of cell structure; how it gains energy; what important molecules it produces.
 
Interesting features of cell structure; how it gains energy; what important molecules it produces.
  
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The Shigella life cycle begins with penetration of colonic mucosa. This results in degradation of the epithelium and acute inflammatory
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colitis in the lamina propria. This causes leakage of blood, inflammation in the colon, and mucus into the intestinal lumen.
  
 
==Ecology==
 
==Ecology==

Revision as of 19:37, 10 November 2006

A Microbial Biorealm page on the genus Shigella

Classification

Higher order taxa

Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae

Species

Shigella boydii; S. dysenteriae; S. flexneri; S. sonnei

Description and significance

Shigiella is a non spore forming gram negative bacteria that aids in the facilitation of intracellular pathogens. It is able to survive the proteases and acids of the intestinal tract and infections to hosts can be caused from a very low dose. As little as 10 to 100 bacteria are needed to cause infection.

Genome structure

The four difference species of Shigella vary greatly in the genomic structure. The largest species S. sonnei contains 4,825,265 base pairs. S. flexneri contains 4,607,203 base pairs, S. boydii contains 4,519,823 base pairs and the smallest species S. dysenteriae contains 4,369, 232 base pairs.

Cell structure and metabolism

Interesting features of cell structure; how it gains energy; what important molecules it produces.

The Shigella life cycle begins with penetration of colonic mucosa. This results in degradation of the epithelium and acute inflammatory colitis in the lamina propria. This causes leakage of blood, inflammation in the colon, and mucus into the intestinal lumen.

Ecology

Habitat; symbiosis; contributions to the environment.

Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Transmission: Fecal-oral transmission is the main path of Shigellosis infection however other modes of transmission include ingestion of contaminated food or water, contact with a contaminated inanimate object, and sexual contact. Outbreaks of Shigellosis infection are common in places where sanitation is poor.

Current Research

Enter summarries of the most rescent research here--at least three required

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Edited by student of Dr. Kirk Bartholomew