Description and Significance
S. ureae is a motile, Gram-positive sporeforming bacteria which is coccoid in shape, its being a coccus is somewhat surprising given its close relation to the Bacillus genus, members of which are rod-shaped. S. ureae is distributed across the globe and is typically found in fertile soils and is especially prevalent in those containing high levels of urea. Its ability to grow in the presence high amounts of urea is due to its ability to convert urea in soil to ammonia through the production of urease. The ability for S. ureae to covert urea to ammonia offers a promising means by which to decrease fertilizer use in agricultural areas. This could be accomplished by rotating a plot of land from being an animal pasture, in which large amounts of urea would be deposited, and then being converted into a field the next year, at which time S. ureae would have converted the urea into ammonia for the new plants to use.
The genome of S. ureae was recently sequenced. The genome contains 3412428 base pairs and is circular in shape. The genome has been found to have a GC content of between 40.0-41.5mol%. Among the better understood elements of S ureae's genome is the SpoIIIE gene which is necessary for the formaton of spores. Interestingly enough, inserting this gene into B. subtilis mutants which cannot form spores reverses the phenotype, allowing them to produce spores.
Cell Structure, Metabolism and Life Cycle
S. ureae tends to form clusters--or sarcinae--of four or more cells. Colonies are circular, gray and opaque and slightly convex. The species is heterotrophic and explicitly aerobic. The organis can grow in a normal nutrient broth, however it performs much better when in the presence of urea, which is likely due to the ease with which glutamic acid and glutamine can be produced from ammonia or ammonium if the medium is alkaline.
Ecology and Pathogenesis
S. ureae is widely distributed in soils, with fertile soils containing as many as 10000 sarcinae/g  While S. ureae is best adapted to a neural habitat, it is tolerant to a pH as high as 10. While S. ureae does not have a specific symbiotic relationship per se, its conversion of urea to ammonia is most likely beneficial most if not all plant life where it is found, as urea can be toxic to plants. In a biogeochemical and environmental sense, S. ureae serves an important role in preventing urea levels from becoming too high in an area, permitting continued inhabitance by other species.
S. ureae is not considered to be pathogenic to any organism at this time. After the organism was isolated from a bronchial biopsy of a child with cystic fibrosis, this notion was called into question. However, it was quickly determined that the existence of S. ureae in the biopsy was unrelated to the child's cystic fibrosis.
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Page authored by Ben Bonson and Joseph Bernth, students of Prof. Jay Lennon at IndianaUniversity.