Streptomyces lividans: Difference between revisions

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==Description and significance==
==Description and significance==
Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated.
Streptomyces lividans is a gram positive, filamentous, soil bacterium. With its high G-C content, this species is known for its genomic plasticity (1). Responsible for the breakdown of organic soil material, Streptomyces are non-pathogenic bacteria that live in colonies. Because of their natural habitat, along with the non-pathogenic character of the species in the genus, S. lividans is used as hosts for the synthesis and secretion of homologous and heterologous proteins (3). The Streptomyces lividans has been extensively studied in laboratories for possible therapeutic uses because of its abundance in multi-drug resistant genes. The Streptomyces genus is responsible for producing a majority of the antibiotics, some immunosuppressants, and anti-tumor agents used today (9).
Include a picture or two (with sources) if you can find them.


==Genome structure==
==Genome structure==

Revision as of 06:38, 29 August 2007

A Microbial Biorealm page on the genus Streptomyces lividans

Classification

Higher order taxa

Domain: Bacteria

Phylum: Actinobacteria

Class: Actinobacteria

Subclass: Actinobacteridae

Order: Actinomycetales

Suborder: Streptomycineae

Family: Streptomycetaceae

Strains: Streptomyces lividans

Species

NCBI: Taxonomy

Genus species: Streptomyces lividans

Description and significance

Streptomyces lividans is a gram positive, filamentous, soil bacterium. With its high G-C content, this species is known for its genomic plasticity (1). Responsible for the breakdown of organic soil material, Streptomyces are non-pathogenic bacteria that live in colonies. Because of their natural habitat, along with the non-pathogenic character of the species in the genus, S. lividans is used as hosts for the synthesis and secretion of homologous and heterologous proteins (3). The Streptomyces lividans has been extensively studied in laboratories for possible therapeutic uses because of its abundance in multi-drug resistant genes. The Streptomyces genus is responsible for producing a majority of the antibiotics, some immunosuppressants, and anti-tumor agents used today (9).

Genome structure

Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?

Cell structure and metabolism

Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

Enter summaries of the most recent research here--at least three required

References

[Sample reference] Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". International Journal of Systematic and Evolutionary Microbiology. 2000. Volume 50. p. 489-500.

Edited by Linnea Shen, student of Rachel Larsen