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==Classification==
==Classification==


Domain; Phylum; Class; Order; family [Others may be used. Use [http://www.ncbi.nlm.nih.gov/Taxonomy/ NCBI] link to find]
Domain: Bacteria, Phylum: Firmicutes, Class: Bacilli, Order: Bacillales, Family: Bacillales Family XII. Incertae Sedis, Genus: Exiguobacterium, Species: Unknown


===Species===
==Habitat Information ==
This soil organism was collected in the Hill Country of Fredericksburg, Texas. The soil was very soft and moist, about 5-6" in depth.
 
''Exiguobacterium'' is found in the Siberian frost<sup>1</sup>, glaciers in Greenland<sup>2</sup>, Yellowstone National Park hot springs<sup>2</sup> and various other locations of extreme temperatures and conditions<sup>2</sup>.
 
==Description and Significance==
 
Our observation of Exiguobacteria is that they are small, irregular rod-shaped bacteria, or coccobacilli. Stains performed on our organism revealed a positive Gram stain and small capsules. This organism was negative for endospores. In regard to the colonies, our observation was that the colonies are yellow, shiny, round, and umbonate with a smooth, entire margin.
 
Collins, et al described ''Exiguobacterium'' in the following ways, "Cells vary in shape from rods (3.2 x 1.2 pm) in the exponential phase to short, almost coccoid forms (1-4 x 1.1 pm) in the stationary phase (Gee et al., 1980). Both rods and coccoid cells are
Gram-positive..."<sup>3</sup> They go on to say that, "Surface colonies on PPYG agar (Gee et al., 1980) are 2 to 3 mm in diameter after 3 d at 25 "C,low convex, orange, opaque, butyrous and easily emulsified...Orange pigment does not diffuse into medium; pigment
production does not occur anaerobically."<sup>3</sup> While we did not originally note that the colonies are opaque and butyrous and that the colony pigment did not diffuse into any of the mediums used when conducting tests on Exiguobacteria, we are in agreement with Collins, et al on these points.


{|
[[File:Colonies.jpeg|200px|thumb|left|Colonies]]
| height="10" bgcolor="#FFDF95" |
'''NCBI: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Tree&id=2&lvl=3&lin=f&keep=1&srchmode=1&unlock Taxonomy]'''
|}


''Genus species''
There are at least 14 species of ''Exiguobacterium'', and they bear hope for bioremediation of a number of pollutants as well as promotion of growth in plants.<sup>4</sup> There is some evidence of this organism eating plastic! <sup>5</sup>


==Habitat Information ==
[[File:Exiguobacterium gram stain3.jpeg|200px|thumb|left|Gram Stain]]
Describe the location and conditions under which the organism was isolated.


==Description and Significance==
[[File:Capsule Stain.jpeg|200px|thumb|left|Capsule Stain]]
Describe the appearance (colonial and cellular), possible antimicrobial activity etc. of the organism, and why the organism might be significant.


==Genome Structure==
==Genome Structure==
Describe the size and content of the genome.  How many chromosomes?  Circular or linear?  Other interesting features?  What is known about its sequence? Include S Ribosomal sequence that you obtained from PCR and sequencing here.


One study found the genome size of the tested species of ''Exiguobacterium'' to range from 2380.0-2729.6 kb.  ''Exiguobacterium sibiricum'' 255-15 has a 3.0 Mbp chromosome and two small plasmids, 4.9 and 1.81 Kbp respectively.  The plasmid content of most other species and strains of ''Exiguobacterium'' is unknown.<sup>2</sup>
16S rRNA genome:
<pre style="white-space: pre-wrap;
white-space: -moz-pre-wrap;
white-space: -pre-wrap;
white-space: -o-pre-wrap;
word-wrap: break-word;">
GCACGCCGCGTGAGTGATGAAGGTTTTCNGANNGTAAAACTCTGTTGTAAGGGAAGAACACGTACGAGAGGAAATGCTCGTACCTTGACGGTACCTTACGAGAAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTGTCCGGAATTATTGGGCGTAAAGCGCGCGCAGGCGGCCTTTTAAGTCTGATGTGAAAGCCCCCGGCTCAACCGGGGAGGGCCATTGGAAACTGGAAGGCTTGAGTACAGAAGAGAAGAGTGGAATTCCACGTGTAGCGGTGAAATGCGTAGAGATGTGGAGGAACACCAGTGGCGAAGGCGACTCTTTGGTCTGTAACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTANATACCCTGGTAGTCCACGCCGTAAACGATGAGTGCTAGGTGTTGGGGGGTTTCCGCCCCTCAGTGCTGAAGCTAACGCATNTANGCACTCCGCCTGGNGAGTACGGCCGCAAGGCTNAAACTCNAAGGANTTGACGGGGACCCGCACAATCGGGGGCACGCCGCGTGAGTGATGAAGGTTTTCNGANNGTAAAACTCTGTTGTAAGGGAAGAACACGTACGAGAGGAAATGCTCGTACCTTGACGGTACCTTACGAGAAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTGTCCGGAATTATTGGGCGTAAAGCGCGCGCAGGCGGCCTTTTAAGTCTGATGTGAAAGCCCCCGGCTCAACCGGGGAGGGCCATTGGAAACTGGAAGGCTTGAGTACAGAAGAGAAGAGTGGAATTCCACGTGTAGCGGTGAAATGCGTAGAGATGTGGAGGAACACCAGTGGCGAAGGCGACTCTTTGGTCTGTAACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTANATACCCTGGTAGTCCACGCCGTAAACGATGAGTGCTAGGTGTTGGGGGGTTTCCGCCCCTCAGTGCTGAAGCTAACGCATNTANGCACTCCGCCTGGNGAGTACGGCCGCAAGGCTNAAACTCNAAGGANTTGACGGGGACCCGCACAATCGGGG
</pre>


==Cell Structure, Metabolism and Life Cycle==
==Cell Structure, Metabolism and Life Cycle==
Interesting features of cell structure; how it gains energy; what important molecules it produces.


Exiguobacteria are facultative anaerobes and fermentative in their metabolism.  This organism ferments glucose and mannitol but not sucrose or lactose.  Cell structure composed of Peptidoglycan de-amino acid, L-Lysine. This organism is positive for menaquinone MK-7, a form of Vitamin K produced by bacteria in the intestine that is important for blood clotting. Cellular fatty acids depending on the strain can include C11;Oi through C18;Oi.


==Physiology and Pathogenesis==
==Physiology and Pathogenesis==
Biochemical characteristics, enzymes made, other characteristics that may be used to identify the organism; contributions to environment (if any).<br>
 
If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.<br><br>
 
Gelatin Hydrolysis:  gelatinase negative (Collins, et al noted the organism to hydrolyze gelatin.<sup>1</sup> )<br>
DNA Hydrolysis:  DNase positive<br> 
[[File:DNA_Hydrolysis.jpeg|200px|thumb|left|DNA Hydrolysis]]
Lipid Hydrolysis:  lipase negative<br>
Phenol Red Broth:<br>
Starch Hydrolysis:  alpha-amylase positive<br>
Casein Hydrolysis:  casease positive<br>
Methyl Red: positive for mixed acids<br>
Voges-Proskauer:  negative<br>
Citrate:  negative<br>
SIM:  sulfur reduction - negative, indole reaction - negative, motility - light, feathery growth which indicates a weak positive<br>
Nitrate Reduction:  does not reduce nitrate (Collins, et al noted the organism to reduce nitrate to nitrite.<sup>1</sup> )<br>
Urea Hydrolysis:  negative<br>
Triple Sugar Iron:  positive glucose and lactose fermentation, does not reduce sulfur (Other tests showed this organism to not ferment lactose.  This test is an outlier on this topic.) <br>
Decarboxylation:  does not produce decarboxylase<br>
Phenylalanine Deaminase:  negative<br>
Oxidase:  negative<br>
Eosin Methylene Blue Agar:  negative<br>
Hektoen Enteric Agar:  negative<br>
MacConkey Agar:  negative<br>
Catalase:  positive<br>
Blood Agar:  gamma hemolysis<br>
Mannitol Salts Agar:  growth, weak positive for mannitol fermentation<br>
Phenylethyl Alcohol Agar:  growth, confirms that organism is Gram positive<br>
Bacitracin/Optochin Susceptibility:  not susceptible to bacitracin or optochin<br>
Bile Esculin:  hydrolyzes esculin<br>
6.5% Salt Tolerance:  negative<br>
Kirby-Bauer Antimicrobial Susceptibility Tests for disinfectants:  strongly susceptible to bleach, lysol, and lavender but only weakly susceptible to tea tree oil<br>
Kirby-Bauer Antimicrobial Susceptibility Tests for antibiotics:  strongly susceptible to ampicillin, linezolid, ticarcillin/clavulanic acid, and ceftazidime<br>
 
 
[[File:Antibiotic_Susceptibility.jpeg|200px|thumb|left|Antibiotic Susceptibility]]
 
Enzymes cleansed from ''Exiguobacterium'' samples are alkaline protease, EKTA catalase, guanosine kinase, ATPases, dehydrogenase, and esterase.<sup>2</sup>
 
 
Exiguobacterium sibiricum may cause human skin infection similar to cutaneous anthrax, and it has been isolated from human skin, wounds, and cerebrospinal fluid.<sup>6</sup>
 
 
The biofilm from Exiguobacterium indicum A11 (NCIM 5531) has been shown to synthesize chondroitin-like molecules.  This could be medically helpful in the future if the strain could be improved upon for higher production.<sup>7</sup>
 
 
Exiguobacterium aurantiacum has been isolated in six patients, three of whom had myeloma, and required the use of a central line.  Another case has been documented of an elderly patient whose cultures grew exiguobacterium acteylicum following a prolonged hospital stay and need for a foley catheter.  The symptom common to each of these patients was fever.  Other symptoms included tachycardia, leukocyturia and cellulitis.  These studies suggest that immunocompromised and elderly patients could be more susceptible to exiguobacterium infections.<sup>8</sup> <sup>9</sup>


==References==
==References==
[Sample reference] [http://ijs.sgmjournals.org/cgi/reprint/50/2/489 Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "''Palaeococcus ferrophilus'' gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". ''International Journal of Systematic and Evolutionary Microbiology''. 2000. Volume 50. p. 489-500.]
 
 
 
<sup>1</sup>Qiu, Yinghua, Sophia Kathariou, and David M. Lubman. "Proteomic Analysis of Cold Adaptation in a Siberian Permafrost Bacterium – Exiguobacterium Sibiricum 255–15 by Two-dimensional Liquid Separation Coupled with Mass Spectrometry." Proteomics 2006.6 (2006): 5221-233. University of Michigan Library. WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Web. 2 Dec. 2015.
 
<sup>2</sup>Vishnivetskaya, Tatiana A., Sophia Kathariou, and James Tiedje. "The Exiguobacterium Genus: Biodiversity and Biogeography." Extremophiles 13.May 2009 (2009): 541-55. Web. 1 Dec. 2015. <http://link.springer.com/article/10.1007/s00792-009-0243-5>.
 
<sup>3</sup>Collins, M.D., B.M. Lund, J.A.E. Farrow, and K.H. Schleifer. "Chemotaxonomic Study of an Alkalophilic Bacterium, Exiguobacterium Aurantiacum Gen. Nov., Sp. Nov." Journal of General Microbiology 129.7 (1983): 2037-042. Microbiology Society. Microbiology Society. Web. 1 Dec. 2015. <br>
 
<sup>4</sup>Ying, Zhang, Shi Ping, and MA Jiong. "Exiguobacterium Spp. and Their Applications in Environmental Remediation." Chinese Journal of Applied & Environmental Biology 2013.05 (2013): 898-904. Web. 1 Dec. 2015.
 
<sup>5</sup>Yang, Y., J. Yang, WM Wu, J. Zhao, Y. Song, L. Gao, R. Yang, and L. Jiang. "Biodegradation and Mineralization of Polystyrene by Plastic-Eating Mealworms: Part 2. Role of Gut Microorganisms." Environmental Science and Technology 49.20 (2015): 12087-2093. PubMed.gov. US National Library of Medicine National Institutes of Health. Web. 1 Dec. 2015.
 
<sup>6</sup>Tena, Daniel, Nora Mariela Martínez, Josefa Casanova, Juan Luis García, Elena Román, María José Medina, and Juan Antonio Sáez-Nieto. "Possible Exiguobacterium Sibiricum Skin Infection in Human." Emerg. Infect. Dis. Emerging Infectious Diseases 20.12 (2014): 2178-179. PMC. National Center for Biotechnology Information, U.S. National Library of Medicine. Web. 2 Dec. 2015.
 
<sup>7</sup>Bothmange, DU, Singhal, RS. "Identification of chondroitin-like molecules from biofilm isolates Exiguobacterium indicum A11 and Lysinibacillus sp. C13." Journal of Applied Microbiology 2015 Oct; 119(4):1046-1056.
 
<sup>8</sup>Pitt, T.L., Malnick, H., Shah,J., Chattaway, M.A. "Characterisation of Exiguobacterium aurantiacum isolates from blood cultures of six patients." Journal Compilation
European Society of Clinical Microbiology and Infectious Diseases, 2007, CMI 13, 937-948.
 
<sup>9</sup>Keynan, Yoav, Weber,Gabriel, Sprecher, Hannah. "Molecular  identification  of Exiguobacterium acetylicum as the aetiological agent of bacteraemia." Journal  of  Medical  Microbiology (2007),56, 563–564.


==Author==
==Author==
Page authored by _____, student of Prof. Kristine Hollingsworth at Austin Community College.
Page authored by Danielle St.Romain and Heather McMillion, students of Prof. Kristine Hollingsworth at Austin Community College.


<!-- Do not remove this line-->[[Category:Pages edited by students of Kristine Hollingsworth at Austin Community College]]
<!-- Do not remove this line-->[[Category:Pages edited by students of Kristine Hollingsworth at Austin Community College]]

Latest revision as of 13:07, 17 October 2017

This student page has not been curated.

Classification

Domain: Bacteria, Phylum: Firmicutes, Class: Bacilli, Order: Bacillales, Family: Bacillales Family XII. Incertae Sedis, Genus: Exiguobacterium, Species: Unknown

Habitat Information

This soil organism was collected in the Hill Country of Fredericksburg, Texas. The soil was very soft and moist, about 5-6" in depth.

Exiguobacterium is found in the Siberian frost1, glaciers in Greenland2, Yellowstone National Park hot springs2 and various other locations of extreme temperatures and conditions2.

Description and Significance

Our observation of Exiguobacteria is that they are small, irregular rod-shaped bacteria, or coccobacilli. Stains performed on our organism revealed a positive Gram stain and small capsules. This organism was negative for endospores. In regard to the colonies, our observation was that the colonies are yellow, shiny, round, and umbonate with a smooth, entire margin.

Collins, et al described Exiguobacterium in the following ways, "Cells vary in shape from rods (3.2 x 1.2 pm) in the exponential phase to short, almost coccoid forms (1-4 x 1.1 pm) in the stationary phase (Gee et al., 1980). Both rods and coccoid cells are Gram-positive..."3 They go on to say that, "Surface colonies on PPYG agar (Gee et al., 1980) are 2 to 3 mm in diameter after 3 d at 25 "C,low convex, orange, opaque, butyrous and easily emulsified...Orange pigment does not diffuse into medium; pigment production does not occur anaerobically."3 While we did not originally note that the colonies are opaque and butyrous and that the colony pigment did not diffuse into any of the mediums used when conducting tests on Exiguobacteria, we are in agreement with Collins, et al on these points.

Colonies

There are at least 14 species of Exiguobacterium, and they bear hope for bioremediation of a number of pollutants as well as promotion of growth in plants.4 There is some evidence of this organism eating plastic! 5

Gram Stain
Capsule Stain

Genome Structure

One study found the genome size of the tested species of Exiguobacterium to range from 2380.0-2729.6 kb. Exiguobacterium sibiricum 255-15 has a 3.0 Mbp chromosome and two small plasmids, 4.9 and 1.81 Kbp respectively. The plasmid content of most other species and strains of Exiguobacterium is unknown.2

16S rRNA genome:

GCACGCCGCGTGAGTGATGAAGGTTTTCNGANNGTAAAACTCTGTTGTAAGGGAAGAACACGTACGAGAGGAAATGCTCGTACCTTGACGGTACCTTACGAGAAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTGTCCGGAATTATTGGGCGTAAAGCGCGCGCAGGCGGCCTTTTAAGTCTGATGTGAAAGCCCCCGGCTCAACCGGGGAGGGCCATTGGAAACTGGAAGGCTTGAGTACAGAAGAGAAGAGTGGAATTCCACGTGTAGCGGTGAAATGCGTAGAGATGTGGAGGAACACCAGTGGCGAAGGCGACTCTTTGGTCTGTAACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTANATACCCTGGTAGTCCACGCCGTAAACGATGAGTGCTAGGTGTTGGGGGGTTTCCGCCCCTCAGTGCTGAAGCTAACGCATNTANGCACTCCGCCTGGNGAGTACGGCCGCAAGGCTNAAACTCNAAGGANTTGACGGGGACCCGCACAATCGGGGGCACGCCGCGTGAGTGATGAAGGTTTTCNGANNGTAAAACTCTGTTGTAAGGGAAGAACACGTACGAGAGGAAATGCTCGTACCTTGACGGTACCTTACGAGAAAGCCACGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTGTCCGGAATTATTGGGCGTAAAGCGCGCGCAGGCGGCCTTTTAAGTCTGATGTGAAAGCCCCCGGCTCAACCGGGGAGGGCCATTGGAAACTGGAAGGCTTGAGTACAGAAGAGAAGAGTGGAATTCCACGTGTAGCGGTGAAATGCGTAGAGATGTGGAGGAACACCAGTGGCGAAGGCGACTCTTTGGTCTGTAACTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACAGGATTANATACCCTGGTAGTCCACGCCGTAAACGATGAGTGCTAGGTGTTGGGGGGTTTCCGCCCCTCAGTGCTGAAGCTAACGCATNTANGCACTCCGCCTGGNGAGTACGGCCGCAAGGCTNAAACTCNAAGGANTTGACGGGGACCCGCACAATCGGGG

Cell Structure, Metabolism and Life Cycle

Exiguobacteria are facultative anaerobes and fermentative in their metabolism. This organism ferments glucose and mannitol but not sucrose or lactose. Cell structure composed of Peptidoglycan de-amino acid, L-Lysine. This organism is positive for menaquinone MK-7, a form of Vitamin K produced by bacteria in the intestine that is important for blood clotting. Cellular fatty acids depending on the strain can include C11;Oi through C18;Oi.

Physiology and Pathogenesis

Gelatin Hydrolysis: gelatinase negative (Collins, et al noted the organism to hydrolyze gelatin.1 )
DNA Hydrolysis: DNase positive

DNA Hydrolysis

Lipid Hydrolysis: lipase negative
Phenol Red Broth:
Starch Hydrolysis: alpha-amylase positive
Casein Hydrolysis: casease positive
Methyl Red: positive for mixed acids
Voges-Proskauer: negative
Citrate: negative
SIM: sulfur reduction - negative, indole reaction - negative, motility - light, feathery growth which indicates a weak positive
Nitrate Reduction: does not reduce nitrate (Collins, et al noted the organism to reduce nitrate to nitrite.1 )
Urea Hydrolysis: negative
Triple Sugar Iron: positive glucose and lactose fermentation, does not reduce sulfur (Other tests showed this organism to not ferment lactose. This test is an outlier on this topic.)
Decarboxylation: does not produce decarboxylase
Phenylalanine Deaminase: negative
Oxidase: negative
Eosin Methylene Blue Agar: negative
Hektoen Enteric Agar: negative
MacConkey Agar: negative
Catalase: positive
Blood Agar: gamma hemolysis
Mannitol Salts Agar: growth, weak positive for mannitol fermentation
Phenylethyl Alcohol Agar: growth, confirms that organism is Gram positive
Bacitracin/Optochin Susceptibility: not susceptible to bacitracin or optochin
Bile Esculin: hydrolyzes esculin
6.5% Salt Tolerance: negative
Kirby-Bauer Antimicrobial Susceptibility Tests for disinfectants: strongly susceptible to bleach, lysol, and lavender but only weakly susceptible to tea tree oil
Kirby-Bauer Antimicrobial Susceptibility Tests for antibiotics: strongly susceptible to ampicillin, linezolid, ticarcillin/clavulanic acid, and ceftazidime


Antibiotic Susceptibility

Enzymes cleansed from Exiguobacterium samples are alkaline protease, EKTA catalase, guanosine kinase, ATPases, dehydrogenase, and esterase.2


Exiguobacterium sibiricum may cause human skin infection similar to cutaneous anthrax, and it has been isolated from human skin, wounds, and cerebrospinal fluid.6


The biofilm from Exiguobacterium indicum A11 (NCIM 5531) has been shown to synthesize chondroitin-like molecules. This could be medically helpful in the future if the strain could be improved upon for higher production.7


Exiguobacterium aurantiacum has been isolated in six patients, three of whom had myeloma, and required the use of a central line. Another case has been documented of an elderly patient whose cultures grew exiguobacterium acteylicum following a prolonged hospital stay and need for a foley catheter. The symptom common to each of these patients was fever. Other symptoms included tachycardia, leukocyturia and cellulitis. These studies suggest that immunocompromised and elderly patients could be more susceptible to exiguobacterium infections.8 9

References

1Qiu, Yinghua, Sophia Kathariou, and David M. Lubman. "Proteomic Analysis of Cold Adaptation in a Siberian Permafrost Bacterium – Exiguobacterium Sibiricum 255–15 by Two-dimensional Liquid Separation Coupled with Mass Spectrometry." Proteomics 2006.6 (2006): 5221-233. University of Michigan Library. WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Web. 2 Dec. 2015.

2Vishnivetskaya, Tatiana A., Sophia Kathariou, and James Tiedje. "The Exiguobacterium Genus: Biodiversity and Biogeography." Extremophiles 13.May 2009 (2009): 541-55. Web. 1 Dec. 2015. <http://link.springer.com/article/10.1007/s00792-009-0243-5>.

3Collins, M.D., B.M. Lund, J.A.E. Farrow, and K.H. Schleifer. "Chemotaxonomic Study of an Alkalophilic Bacterium, Exiguobacterium Aurantiacum Gen. Nov., Sp. Nov." Journal of General Microbiology 129.7 (1983): 2037-042. Microbiology Society. Microbiology Society. Web. 1 Dec. 2015.

4Ying, Zhang, Shi Ping, and MA Jiong. "Exiguobacterium Spp. and Their Applications in Environmental Remediation." Chinese Journal of Applied & Environmental Biology 2013.05 (2013): 898-904. Web. 1 Dec. 2015.

5Yang, Y., J. Yang, WM Wu, J. Zhao, Y. Song, L. Gao, R. Yang, and L. Jiang. "Biodegradation and Mineralization of Polystyrene by Plastic-Eating Mealworms: Part 2. Role of Gut Microorganisms." Environmental Science and Technology 49.20 (2015): 12087-2093. PubMed.gov. US National Library of Medicine National Institutes of Health. Web. 1 Dec. 2015.

6Tena, Daniel, Nora Mariela Martínez, Josefa Casanova, Juan Luis García, Elena Román, María José Medina, and Juan Antonio Sáez-Nieto. "Possible Exiguobacterium Sibiricum Skin Infection in Human." Emerg. Infect. Dis. Emerging Infectious Diseases 20.12 (2014): 2178-179. PMC. National Center for Biotechnology Information, U.S. National Library of Medicine. Web. 2 Dec. 2015.

7Bothmange, DU, Singhal, RS. "Identification of chondroitin-like molecules from biofilm isolates Exiguobacterium indicum A11 and Lysinibacillus sp. C13." Journal of Applied Microbiology 2015 Oct; 119(4):1046-1056.

8Pitt, T.L., Malnick, H., Shah,J., Chattaway, M.A. "Characterisation of Exiguobacterium aurantiacum isolates from blood cultures of six patients." Journal Compilation European Society of Clinical Microbiology and Infectious Diseases, 2007, CMI 13, 937-948.

9Keynan, Yoav, Weber,Gabriel, Sprecher, Hannah. "Molecular identification of Exiguobacterium acetylicum as the aetiological agent of bacteraemia." Journal of Medical Microbiology (2007),56, 563–564.

Author

Page authored by Danielle St.Romain and Heather McMillion, students of Prof. Kristine Hollingsworth at Austin Community College.