Treponema pallidum

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A Microbial Biorealm page on the genus Treponema pallidum

Classification

Higher order taxa

Eubacteria; Spirochaetes; Spirochaetes; Spirochaetales; Spirochaetaceae; Treponema

Species

Treponema pallidum, T. pertenue, T. endemicum

NCBI: Taxonomy

Description and significance

Genome structure

Cell structure and metabolism

Ecology

Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.

Pathology

How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.

Application to Biotechnology

Does this organism produce any useful compounds or enzymes? What are they and how are they used?

Current Research

Enter summaries of the most recent research here--at least three required

References

Rebecca E. LaFond and Sheila A. Lukehart "Biological Basis for Syphilis" Departments of Pathobiology, Medicine, University of Washington, Seattle, Washington 2006 American Society for Microbiology

Treponema pallidum subsp. pallidum str. Nichols (Project ID: 5) at US DOE Joint Genome Institute http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=5

Fraser CM,Norris SJ,Weinstock GM,White O, Sutton GG,Dodson R,Gwinn M,Hickey EK,Clayton R,Ketchum KA,Sodergren E,Hardham JM,McLeod MP,Salzberg S,Peterson J,Khalak H,Richardson D,Howell JK,Chidambaram M,Utterback T,McDonald L,Artiach P,Bowman C,Cotton MD,Fujii C,Garland S,Hatch B,Horst K, Roberts K,Sandusky M,Weidman J,Smith HO,Venter JC. "Complete genome sequence of Treponema pallidum, the syphilis spirochete" 1998 Institute for Genomic Research, Rockville, MD 20850, USA.

Greene SR, Stamm LV, Hardham JM, Young NR, Frye JG "Identification, sequences, and expression of Treponema pallidum chemotaxis genes" 1997 Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill

Weinstock GM, Hardham JM, McLeod MP, Sodergren EJ, Norris SJ "The genome of Treponema pallidum: new light on the agent of syphilis" 1998 Department of Microbiology and Molecular Genetics, University of Texas Medical School, Houston

Edited by Jasmin Eshragh, student of Rachel Larsen at UCSD.