User:S4289005

From MicrobeWiki, the student-edited microbiology resource

Thomas Clarkson, Bench D, 31/08/16.


Classification

re re re

Higher order taxa

Bacteria – Bacteria – Bacteroidetes – Bacteroidetes – Bacteroidales – Porphyromonas - gingivalis

Species

The species is Porphyromonas gingivalis, and it has a number of different type strains. These are 2561 T , ATCC 33277 T , BCRC 14417 T , CCRC 14417 T , CCUG 25893 T , CCUG 25928 T , CIP 103683 T , Coykendall 2561T , DSM 20709 T , JCM 12257 T , KCTC 5121T , NCTC 11834 T , Slots 2561 T , Slots' 2561 T , Slots' strain 2561 T (1).

' 'it is a strain[1]

or is it a strain?[1]

Description and significance

Porphyromonas gingivalis, is a gram-negative rod bacteria. It is non-motile, and found on and within the gingival epithelial cells in the oral cavity. It is dark-pigmented, asaccharolytic, and requires iron from heme for growth (2). Its relative importance comes from its implication as the most common cause of periodontitis. A number of articles have demonstrated its role as the aetiological agent. Overall, around 85% of diseased tissues have been shown to house P. gingivalis (2). Additionally it is not often found in healthy tissue, and the depth of the surface pits it forms from infection is strongly correlated to numbers of P. gingivalis present at the site (2). The bacteria cannot be found in the environment, due to its specific metabolic requirements, It can however be cultured on a blood agar plate (2).

Genome structure

Select a strain for which genome information (e.g. size, plasmids, distinct genes, etc.) is available.

Cell structure and metabolism

Cell wall, biofilm formation, motility, metabolic functions.

Ecology

Aerobe/anaerobe, habitat (location in the oral cavity, potential other environments) and microbe/host interactions.REEEEEEEEEEEEEEEEEEEEEEEEE[1]

Pathology

Do these microorganisms cause disease in the oral cavity or elsewhere?

Application to biotechnology

Bioengineering, biotechnologically relevant enzyme/compound production, drug targets,…

Current research

Summarise some of the most recent discoveries regarding this species.

References

References examples

1. Sahm, K., MacGregor, B.J., Jørgensen, B.B., and Stahl, D.A. (1999) Sulphate reduction and vertical distribution of sulphate-reducing bacteria quantified by rRNA slotblot hybridization in a coastal marine sediment. Environ Microbiol 1: 65-74.

2. Human Oral Microbiome

3. Honda, T., Takahashi, N., Miyauchi, S., yamazaki, K. (2012) Porphyromonas gingivalis lipopolysaccharide induces miR-146a without altering the production of inflammatory cytokines. Biochemical and Biophysical Research Communications 2.

NOTE DO NOT REFERENCE LIKES THIS, USE THE FIRST THREE REFERENCES, AND ALSO FOR CITATIONS USE THE SUPERSCRIPT COMMAND

This page is written by Thomas Clarkson for the MICR3004 course, Semester 2, 2016