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(Genome structure)
(Cell structure and metabolism)
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==Cell structure and metabolism==
==Cell structure and metabolism==
Cell wall, biofilm formation, motility, metabolic functions.  
Cell wall, biofilm formation, motility, metabolic functions.

Revision as of 00:50, 22 September 2016

Jessekah Butterworth Bench B Date [1]


Higher order taxa

Bacteria – Proteobacteria – Betaproteobacteria – Neisseriales – Neisseriaceae – Kingella


Kingella oralis

Strain: strain UB-38 = ATCC 51147 = CCUG 30450 = CIP 103803.[1]

Description and significance

Kingella oralis is a gram-negative, bacilli bacteria that was first observed by Chen et al in 1989, who were investigating the presence of Eikenella corrodens in the human oral cavity.[2] This isolate was further investigated by Dewhirst et al in 1993, using Eikenella corrodens-selective medium containing 1 μg of clindamycin per ml. [3] Several characteristics distinguished the two species from each other including colony morphology on agar and acid production from sugars.

Kingella oralis is found in both supragingival and subgingival plaque, as well as in mucosa and saliva.[4]

Give a general description of the species (e.g. where/when was it first discovered, where is it commonly found, has it been cultured, functional role, type of bacterium [Gram+/-], morphology, etc.) and explain why it is important to study this microorganism. Examples of citations [1], [2]

Genome structure

The representative K. oralis strain ATCC 51147, has a total genome size of 2.41Mb consisting of 2435 genes which encode approximately 2315 proteins and 6 rRNAs. [5] It has a GC% content of 54.3%.

The genome assembly consists of 5 scaffolds that contain no gaps in between and 12 contigs, with a contig N50 of 792,850.[6] K. oralis does not form chromosomes and contains no plasmids either.

Cell structure and metabolism

Cell wall, biofilm formation, motility, metabolic functions.


Aerobe/anaerobe, habitat (location in the oral cavity, potential other environments) and microbe/host interactions.


Do these microorganisms cause disease in the oral cavity or elsewhere?

Application to biotechnology

Bioengineering, biotechnologically relevant enzyme/compound production, drug targets,…

Current research

Summarise some of the most recent discoveries regarding this species.


1. List of Prokaryotic names with standing in nomenclature

2. Chen, C., Dunford, RG., Reynolds HS., Zambon JJ. (1989) Eikenella corrodens in the human oral cavity. J Peridontal 60:611-616.

3. Dewhirst, FE., Chen, C., Paster, BJ., Zambon, JJ. (1993) Phylogeny of Species in the Family Neisseriaceae Isolated from Human Dental Plaque and Description of Kingella orale sp.nov. Internation Journal of Systematic Bacteriology 43:490-499.

4. Chen, C. (1996) Distribution of a newly described species, Kingella oralis, in the human oral cavity. Oral Microbiol Immunol 11:425-427.

5. NCBI Genome Assembly Annotation: Kingella oralis

6. NCBI Global Genome Statistics: Kingella oralis

  1. MICR3004

This page is written by Jessekah Butterworth for the MICR3004 course, Semester 2, 2016