View source for Gas gangrene (Clostridial myonecrosis)

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==Section==
[[Image:Gas gangrene.jpg|thumb|300px|right|47 year-old-man with gas gangrene in the right leg. Picture was taken before hemipelvectomy. Large necrotic blisters of CO<sub>2</sub> caused by <i>Clostridium</i> are visible [https://casesjournal.biomedcentral.com/articles/10.1186/1757-1626-1-252].]]
<br>By Yiyi Ma<br><br>

[[Image:kappatox1.jpeg|thumb|200px|right|Structure of alpha-toxin. Two separate domains are pictured with N- and C-domains and Zn2+ and possible Ca2+ ions. [http://ac.els-cdn.com/S1075996499901919/1-s2.0-S1075996499901919-main.pdf?_tid=843ae610-28a7-11e7-a31e-00000aacb35e&acdnat=1493008740_a6dead265896beb6ba4f37cf4b555556].]]

[[Image:pore.png|thumb|300px|right|Mechanism of pore formation by PFO on eukaryotic lipid bilayer. Association between lipid bilayer and PFO is greatest on edges of the membrane, where cholesterol is most accessible. [http://www.mdpi.com/2072-6651/7/5/1702/htm].]]

[[Image:alphatox2.png|thumb|300px|right|The structure of PFO. β-barrels are evident in the four separate domains. Domain 1 and 2 are purple, domain 3 is green and domain 4 is red. [http://www.mdpi.com/2072-6651/7/5/1702/htm].]]


[[Image:alphatox1.png|thumb|300px|right|Alpha-toxin shown interacting with lipid bilayer of eukaryotic membrane. Interactions with ions are shown, denoting the critical role of Ca2+ and Zn2+ in the function of alpha-toxin.  [http://ac.els-cdn.com/S1075996499901919/1-s2.0-S1075996499901919-main.pdf?_tid=843ae610-28a7-11e7-a31e-00000aacb35e&acdnat=1493008740_a6dead265896beb6ba4f37cf4b555556 ].]]

[[Image:oxygen.png|thumb|300px|right|Use of hyperbaric oxygen therapy in wound healing of 53-year-old diabetic patient with spontaneous gas gangrene. Leg was preserved with use of hyperbaric oxygen. Healthy tissue growth can be seen last image. [ttp://www.ijps.org/article.asp?issn=0970-0358;year=2012;volume=45;issue=2;spage=316;epage=324;aulast=Bhutani].]]

<br>By Yiyi Ma<br><br>
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<br><b>Legend/credit:</b> Electron micrograph of the Ebola Zaire virus. This was the first photo ever taken of the virus, on 10/13/1976. By Dr. F.A. Murphy, now at U.C. Davis, then at the [http://www.cdc.gov/ CDC].
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==Section 4==

==Conclusion==

==References==
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<br><br>Authored for BIOL 238 Microbiology, taught by [mailto:slonczewski@kenyon.edu Joan Slonczewski], 2017, [http://www.kenyon.edu/index.xml Kenyon College].