Targeted Gene Therapy Via Lentiviral Vectors: Difference between revisions

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<br>By Drew Albrecht<br>
<br>By Drew Albrecht<br>
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<br>Gene therapy is the (HELP). Genetic disorders like cystic fibrosis, phenylketonuria, sickle-cell anemia, and many more, are a result of mutated or absent genes. The goal of gene therapy is to treat or cure such diseases via genetic modification of the cells in an affected individual. This genetic modification can rewire the cells to either produce a therapeutic effect[Kaji] or simply just replace the mutated or missing DNA[Lai].




Revision as of 00:44, 12 April 2022

Gene Therapy Overview

Figure 1. Schematic drawing of ex vivo gene therapy FDA


By Drew Albrecht


Gene therapy is the (HELP). Genetic disorders like cystic fibrosis, phenylketonuria, sickle-cell anemia, and many more, are a result of mutated or absent genes. The goal of gene therapy is to treat or cure such diseases via genetic modification of the cells in an affected individual. This genetic modification can rewire the cells to either produce a therapeutic effect[Kaji] or simply just replace the mutated or missing DNA[Lai].




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Superscript: Fe3+

Lentiviruses



Sample citations: [1] [2]

A citation code consists of a hyperlinked reference within "ref" begin and end codes.
To repeat the citation for other statements, the reference needs to have a names: "<ref name=aa>"
The repeated citation works like this, with a forward slash.[1]

  1. ↑ 1.0 1.1 Hodgkin, J. and Partridge, F.A. "Caenorhabditis elegans meets microsporidia: the nematode killers from Paris." 2008. PLoS Biology 6:2634-2637.
  2. ↑ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.
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