Fannyhessea vaginae: Difference between revisions
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Fannyhessea Vaginae (formerly atopobium vaginae) is a gram positive cocci shaped bacterium highly specific to Bacterial Vaginosis (BV) (Lu ́cia G. V. Sousa et al, 2021). | Fannyhessea Vaginae (formerly atopobium vaginae) is a gram positive cocci shaped bacterium highly specific to Bacterial Vaginosis (BV) (Lu ́cia G. V. Sousa et al, 2021). | ||
As an anaerobe (low to no oxygen) F. Vaginae creates polymicrobial biofilms that layer the vaginal epithelial cells helping to maintain the anaerobic conditions (Lu ́cia G. V. Sousa et al, 2021). | As an anaerobe (low to no oxygen) F. Vaginae creates polymicrobial biofilms that layer the vaginal epithelial cells helping to maintain the anaerobic conditions (Lu ́cia G. V. Sousa et al, 2021). The Biofilms produced by this microbe serves as a diagnostic marker for BV which is vital as most detection methods for BV fail. | ||
==Genome Structure== | ==Genome Structure== | ||
Revision as of 02:24, 7 November 2023
Classification
Bacteria; Actinimycetota; Actinomycetes ; Actinomycetales; Actinomycetaceae; Fannyhessea
Species
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NCBI: [1] |
Fannyhessea Vaginae
Description and Significance
Fannyhessea Vaginae (formerly atopobium vaginae) is a gram positive cocci shaped bacterium highly specific to Bacterial Vaginosis (BV) (Lu ́cia G. V. Sousa et al, 2021).
As an anaerobe (low to no oxygen) F. Vaginae creates polymicrobial biofilms that layer the vaginal epithelial cells helping to maintain the anaerobic conditions (Lu ́cia G. V. Sousa et al, 2021). The Biofilms produced by this microbe serves as a diagnostic marker for BV which is vital as most detection methods for BV fail.
Genome Structure
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?
Cell Structure, Metabolism and Life Cycle
This organism uses utilizes carbohydrates through a glycolysis and the pentose phosphorous pathway. Anaerobic glycolytic pathway breaks down glycerin-p down to pyruvate to be used in the production of energy. Pentose Phosphorous pathway breaks down fructose-6p that can end up In the input of the glycolytic pathway. In a further complex fashion during the break down via the glycerin-p, at the pyruvate stage this organism can switch its metabolism into a anabolic pathway to build the amino acid methionine from the serine intermediate.
Ecology and Pathogenesis
Habitat; symbiosis; biogeochemical significance; contributions to environment.
If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
References
Author
Page authored by _____, student of Prof. Bradley Tolar at UNC Wilmington.
