Parvovirus B19: Difference between revisions

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<b>By Grace Potter <br>
<b>By Grace Potter <br>


<i>Parvovirus B19</i> is the only member of the <i>Parvoviridae</i> family that has been found to infect human hosts.<ref name=ncbi/> It was discovered in 1974, when a research group looking at hepatitis B surface antigens found a serum sample with unexpected results.<ref name=ncbi/> Another lab in Japan described a similar virus in 1979 that they called "Nakatami".<ref name=ncbi/> When compared, the two were found to be identical.<ref name=ncbi/>
<i>Parvovirus B19</i> is the only member of the <i>Parvoviridae</i> family that has been found to infect human hosts.<ref name=ncbi>[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC118081/#:~:text=Parvovirus%20B19%20(B19)%20was%20discovered%20serendipitously%20in%201974%20and%20is,hematologic%20status%20of%20the%20host. Heegaard, E.D. and Brown, K.E. "Human Parvovirus B19." 2002. Clinical Microbiology Review 15(3):485-505.]</ref> It was discovered in 1974, when a research group looking at hepatitis B surface antigens found a serum sample with unexpected results.<ref name=ncbi/> Another lab in Japan described a similar virus in 1979 that they called "Nakatami".<ref name=ncbi/> When compared, the two were found to be identical.<ref name=ncbi/>


In 1985 this virus was officially recognized as a member of the <i>Parvoviridae</i> family due to its similarities in genome size and density.<ref name=ncbi/>
In 1985 this virus was officially recognized as a member of the <i>Parvoviridae</i> family due to its similarities in genome size and density.<ref name=ncbi/>

Revision as of 20:44, 5 April 2024

Background

The life cycle of Canine Parvovirus. Photo credit: [1]

By Grace Potter

Parvovirus B19 is the only member of the Parvoviridae family that has been found to infect human hosts.[1] It was discovered in 1974, when a research group looking at hepatitis B surface antigens found a serum sample with unexpected results.[1] Another lab in Japan described a similar virus in 1979 that they called "Nakatami".[1] When compared, the two were found to be identical.[1]

In 1985 this virus was officially recognized as a member of the Parvoviridae family due to its similarities in genome size and density.[1]

Section 1

Include some current research, with at least one figure showing data.

Parvoviridae

Genome Structure

The Parvovirus genome is a single strand of DNA with 5,596 nucleotides, 4,830 of which are coding regions.[1] This region contains 2 large open reading frames.[1] One large non-structural protein is coded by one open reading frame, and the second reading frame codes for 2 capsid proteins.[1]

Section 3

Include some current research, with at least one figure showing data.

Section 4

Conclusion

References



Authored for BIOL 238 Microbiology, taught by Joan Slonczewski,at Kenyon College,2024