Long covid and the brain: Difference between revisions

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<b>Brain Fog:</b> Brain fog a range of neuron-cognitive symptoms that including forgetfulness, problem of focusing, concentrating, and paying attentions. These symptoms can last for weeks and months after the patient get initial infections<ref>covid19.nih.gov. (n.d.). Shining a Light on Long COVID Brain Fog | NIH COVID-19 Research. [online] Available at: https://covid19.nih.gov/news-and-stories/shining-light-long-covid-brain-fog#:~:text=%E2%80%9CBrain%20fog%E2%80%9D%20is%20a%20range.</ref>.
<b>Brain Fog:</b> Brain fog a range of neuron-cognitive symptoms that including forgetfulness, problem of focusing, concentrating, and paying attentions. These symptoms can last for weeks and months after the patient get initial infections<ref>covid19.nih.gov. (n.d.). Shining a Light on Long COVID Brain Fog | NIH COVID-19 Research. [online] Available at: https://covid19.nih.gov/news-and-stories/shining-light-long-covid-brain-fog#:~:text=%E2%80%9CBrain%20fog%E2%80%9D%20is%20a%20range.</ref>.


<b>Sleep Disturbance:</b> Approximately 40% of people with long COVID reported major changes of their sleep after COVID-19. People have experienced COVID-19-associated sleep disorders including insomnia and restless leg syndrome<ref>Tony, A.A., Tony, E.AE., Ali, S.B., Ezzeldin, A.M. and Mahmoud, A.A. (2020). COVID-19-associated sleep disorders: A case report. Neurobiology of Sleep and Circadian Rhythms, 9, p.100057. doi:https://doi.org/10.1016/j.nbscr.2020.100057.</ref>.
<b>Sleep Disturbance:</b> Approximately 40% of people with long COVID reported major changes of their sleep after COVID-19. People have experienced COVID-19-associated sleep disorders including insomnia and restless leg syndrome<ref>Tony, A.A., Tony, E.AE., Ali, S.B., Ezzeldin, A.M. and Mahmoud, A.A. (2020). COVID-19-associated sleep disorders: A case report. Neurobiology of Sleep and Circadian Rhythms, 9, p.100057. doi:https://doi.org/10.1016/j.nbscr.2020.100057.</ref><ref>www.ninds.nih.gov. (n.d.). COVID-19 and the Nervous System | National Institute of Neurological Disorders and Stroke. [online] Available at: https://www.ninds.nih.gov/current-research/coronavirus-and-ninds/covid-19-and-nervous-system#:~:text=Since%20COVID%2D19%20can%20affect.</ref>.


<b>Anxiety,depression, and stress:</b>
<b>Anxiety,depression, and stress:</b>

Revision as of 23:44, 11 April 2024

Introduction

Overview of long COVID

Long COVID or Post COVID conditions, also known as post-acute sequelae of SARS-CoV-2 infection(PASC),refers to a range of symptoms that continue for weeks, months, or even years after the patient initially recovering from the coronavirus disease(COVID-19). The condition can affect anyone who was infected by COVID-19, regardless of the severity of their initial infection. The symptoms of long term COVID can various between each individual and be very complicated because it sometimes impact multiple organism systems. The complexity of the symptoms often leads to post-COVID conditions being diagnosed as other diseases.

Fig.1

Although COVID is primarily target to respiration systems, there is growing evidence that COVID-19 can have long-term effects on the brain, including potential links to increased risks of neurological diseases like Parkinson's and Alzheimer's disease in the future. Corona virus was unusual because it had been found the virus across blood-brain barrier. The dissecting samples shows the virus is preserved in brain tissue over months and it is still active[1].

Neurological Symptoms

Diagnosis and Evaluation

Diagnose Long COVID is an exclusion process, indicating that it is only diagnosed after doctor excluding all the possible disease or causes that lead the symptoms. It is a tricky process that for sometimes doctors will reveal some hidden diseases that even the patient doesn't know before. Due to the various symptoms patient experienced, there is no standard treatment for long COVID.

Common Symptoms

Brain Fog: Brain fog a range of neuron-cognitive symptoms that including forgetfulness, problem of focusing, concentrating, and paying attentions. These symptoms can last for weeks and months after the patient get initial infections[2].

Sleep Disturbance: Approximately 40% of people with long COVID reported major changes of their sleep after COVID-19. People have experienced COVID-19-associated sleep disorders including insomnia and restless leg syndrome[3][4].

Anxiety,depression, and stress:

Post-exertional malaise:

Sensitivity and Pain:

Headache:

Dizziness and Fainting:

Movement issue:

Pathophysiology

Nasal Infections

Breathing Pathway

COVID and the Nervous System

Brain "Fog"

Alzheimer's disease

Parkinson's disease

Treatment and Management

  1. Chertow, D., Stein, S., Ramelli, S., Grazioli, A., Chung, J.-Y., Singh, M., Yinda, C.K., Winkler, C., Dickey, J., Ylaya, K., Ko, S.H., Platt, A., Burbelo, P., Quezado, M., Pittaluga, S., Purcell, M., Munster, V., Belinky, F., Ramos-Benitez, M. and Boritz, E. (2021). SARS-CoV-2 infection and persistence throughout the human body and brai. [online] Europe PMC. Available at: https://europepmc.org/article/ppr/ppr434451.
  2. covid19.nih.gov. (n.d.). Shining a Light on Long COVID Brain Fog | NIH COVID-19 Research. [online] Available at: https://covid19.nih.gov/news-and-stories/shining-light-long-covid-brain-fog#:~:text=%E2%80%9CBrain%20fog%E2%80%9D%20is%20a%20range.
  3. Tony, A.A., Tony, E.AE., Ali, S.B., Ezzeldin, A.M. and Mahmoud, A.A. (2020). COVID-19-associated sleep disorders: A case report. Neurobiology of Sleep and Circadian Rhythms, 9, p.100057. doi:https://doi.org/10.1016/j.nbscr.2020.100057.
  4. www.ninds.nih.gov. (n.d.). COVID-19 and the Nervous System | National Institute of Neurological Disorders and Stroke. [online] Available at: https://www.ninds.nih.gov/current-research/coronavirus-and-ninds/covid-19-and-nervous-system#:~:text=Since%20COVID%2D19%20can%20affect.