Providencia alcalifaciens: Difference between revisions
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==Description and significance== | ==Description and significance== | ||
''P. alcalifaciens'' is a rod-shaped gram-negative bacterium. This bacterium is associated with diarrhea in children and travelers. It is found in the gastrointestinal tract. Scientists have found that some strains of ''P. alcalifaciens'' are invasive to HEp-2 cells, Vero, and Y1 adrenal cell lines in eukaryotes. The amounts of the HEp-2 cells were seen to decrease within 6 hours after infection. The microbe causes actin condensation in the invaded cells. ''P. alcalifaciens'' thrives in environments around 37 degrees celsius especially for invasion. A study found that the microfilament inhibitor cytochalasin D inhibits the invasion by ''P. alcalifaciens''. | |||
==Genome structure== | ==Genome structure== | ||
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According to the NCBI database, ''P. alcalifaciens'' is made up of 4,022 protein sequences encoded in a 4.03 Mb genome. The GC content is 41.8% <sup>2</sup>. The genome was sequenced in 2008, isolated from human feces. Most | According to the NCBI database, ''P. alcalifaciens'' is made up of 4,022 protein sequences encoded in a 4.03 Mb genome. The GC content is 41.8% <sup>2</sup>. The genome was sequenced in 2008, isolated from human feces. Most ''P. alcalifaciens'' strains are organized in plasmids. Scientists are trying to determine whether the invasiveness and genome structure of the different bacterial strains have certain correlations concerning the presence of plasmids. | ||
==Cell and colony structure== | ==Cell and colony structure== | ||
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==Ecology== | ==Ecology== | ||
''P. alcalifaciens'' is found in many different human and animal reservoirs. It is usually found in the gut or digestive tract and mostly seen in travelers who have traveled to developing countries. Young children and the elderly are at a higher risk for this infection. | |||
==Pathology== | ==Pathology== | ||
Infection symptoms include diarrhea, abdominal pain, and fever. | Infection symptoms include diarrhea, abdominal pain, and fever. ''P. alcalifaciens'' is believed to be involved in gastroenteritis. This bacteria is associated with travelers overseas. A problem of treating the infection from ''P. alcalifaciens'' is arising due to antibiotic resistance. | ||
==References== | ==References== | ||
Revision as of 16:23, 9 May 2012
A Microbial Biorealm page on the genus Providencia alcalifaciens
Classification
Higher order taxa
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Providencia
Species
Providencia alcalifaciens
|
NCBI: [2] |
Description and significance
P. alcalifaciens is a rod-shaped gram-negative bacterium. This bacterium is associated with diarrhea in children and travelers. It is found in the gastrointestinal tract. Scientists have found that some strains of P. alcalifaciens are invasive to HEp-2 cells, Vero, and Y1 adrenal cell lines in eukaryotes. The amounts of the HEp-2 cells were seen to decrease within 6 hours after infection. The microbe causes actin condensation in the invaded cells. P. alcalifaciens thrives in environments around 37 degrees celsius especially for invasion. A study found that the microfilament inhibitor cytochalasin D inhibits the invasion by P. alcalifaciens.
Genome structure
|
NCBI: [3] |
According to the NCBI database, P. alcalifaciens is made up of 4,022 protein sequences encoded in a 4.03 Mb genome. The GC content is 41.8% 2. The genome was sequenced in 2008, isolated from human feces. Most P. alcalifaciens strains are organized in plasmids. Scientists are trying to determine whether the invasiveness and genome structure of the different bacterial strains have certain correlations concerning the presence of plasmids.
Cell and colony structure
Metabolism
Ecology
P. alcalifaciens is found in many different human and animal reservoirs. It is usually found in the gut or digestive tract and mostly seen in travelers who have traveled to developing countries. Young children and the elderly are at a higher risk for this infection.
Pathology
Infection symptoms include diarrhea, abdominal pain, and fever. P. alcalifaciens is believed to be involved in gastroenteritis. This bacteria is associated with travelers overseas. A problem of treating the infection from P. alcalifaciens is arising due to antibiotic resistance.
References
Edited by Victoria Hughes of Dr. Lisa R. Moore, University of Southern Maine, Department of Biological Sciences, http://www.usm.maine.edu/bio
![[1]](http://en.wikipedia.org/wiki/File:Providencia_alcalifaciens.jpg){kind=link}