Ralstonia insidiosa: Difference between revisions

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[[Image:Filename.jpg|thumb|300px|right|Legend. Image credit: Name or Publication.]]
[[Image: sam.jpeg |thumb|300px|right|Transmission electron photomicrograph of a typical flagellated (archaellum) Candidatus <i>Nitrosarchaeum limnium</i> cell. Image credit: J. Herrmann, Stanford Univ.]]
 
   
   


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Domain: Bacteria
Domain: Bacteria
Phylum: Pseudomonadota
Phylum: Pseudomonadota
Class: Betaproteobacteria
Class: Betaproteobacteria
Order: Burkholderiales
Order: Burkholderiales
Family: Burkholderiaceae
Family: Burkholderiaceae
Genus: Ralstonia
Genus: Ralstonia
Species: R. insidiosa
Species: R. insidiosa
   
   
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''Genus species''
Ralstonia insidiosa
Ralstonia insidiosa


==Description and Significance==
==Description and Significance==


Describe the appearance, habitat, etc. of the organism, and why you think it is important.
<i>Ralstonia insidiosa</i> is a bacillus shaped bacterium and can be found in ponds, rivers, soils, and sludge naturally. It can also be found in drinking water, industry purified water, and most importantly, hospital water supplies. This organism is important to understand because it can cause sepsis and other infections in patients within hospital settings.
 


==Genome Structure==
==Genome Structure==


Describe the size and content of the genome. How many chromosomes?  Circular or linear?  Other interesting features?  What is known about its sequence?
This bacteria has two circular chromosomes, one being primary that contains 4 million base pairs, and the other being secondary that contains 2 million base pairs. It also has one 50 kb plasmids. It contains 16S rRNA.
 


==Cell Structure, Metabolism and Life Cycle==
==Cell Structure, Metabolism and Life Cycle==


Interesting features of cell structure; how it gains energy; what important molecules it produces.
It is: aerobic, oxidase positive, gram negative, and classified as a non fermentative bacillus. It is a chemoheterotroph that relies on other carbon sources for cell growth. R. <i>insidiosa</i> can use hydrocarbons from chemical compounds normally found in disinfectants as a source of carbon. It can also do this in hypoxic environments.
 


==Ecology and Pathogenesis==
==Ecology and Pathogenesis==


Habitat; symbiosis; biogeochemical significance; contributions to environment.<br>
It does not normally affect healthy humans, but those who are already immunocompromised. It is normally found in hospitals and in the lungs of patients that have cystic fibrosis. Patients normally are infected via contaminated water and sterile products. This happens because R. <i>insidosa</i> is very small and is able to pass through 0.2mm filters that are used for sterilization.


If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.<br><br>
==References==


Fang, Qingqing, et al. “Nosocomial Bloodstream Infection and the Emerging Carbapenem-Resistant Pathogen Ralstonia Insidiosa - BMC Infectious Diseases.” BioMed Central, BioMed Central, 23 Apr. 2019, https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-019-3985-4.
 
==References==


[Sample reference] [http://ijs.sgmjournals.org/cgi/reprint/50/2/489 Takai, K., Sugai, A., Itoh, T., and Horikoshi, K. "''Palaeococcus ferrophilus'' gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney". ''International Journal of Systematic and Evolutionary Microbiology''. 2000. Volume 50. p. 489-500.]
Ryan, Michael P., and Catherine C. Adley. “The Antibiotic Susceptibility of Water-Based Bacteria Ralstonia Pickettii and Ralstonia Insidiosa.” Journal of Medical Microbiology, Microbiology Society, 1 July 2013, https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.054759-0.  


Xu, Yunfeng, et al. “Genome Sequences of Ralstonia Insidiosa Type Strain ATCC 49129 and Strain FC1138, a Strong Biofilm Producer Isolated from a Fresh-Cut Produce-Processing Plant.” Genome Announcements, U.S. National Library of Medicine, 18 Aug. 2016, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991715/#:~:text=It%20contains%205%2C820%20protein%2Dcoding,large%20plasmid%20(50%2C770%20bp).


==Author==
==Author==


Page authored by _____, student of Prof. Bradley Tolar at UNC Wilmington.
Page authored by Samarah Jeffrey, student of Prof. Bradley Tolar at UNC Wilmington.


   
   


<!-- Do not remove this line-->[[Category:Pages edited by students of Bradley Tolar at UNC Wilmington]]
<!-- Do not remove this line-->[[Category:Pages edited by students of Bradley Tolar at UNC Wilmington]]

Latest revision as of 19:02, 11 December 2022

This student page has not been curated.
Transmission electron photomicrograph of a typical flagellated (archaellum) Candidatus Nitrosarchaeum limnium cell. Image credit: J. Herrmann, Stanford Univ.


Classification

Domain: Bacteria

Phylum: Pseudomonadota

Class: Betaproteobacteria

Order: Burkholderiales

Family: Burkholderiaceae

Genus: Ralstonia

Species: R. insidiosa


Species

NCBI: [1]


Ralstonia insidiosa

Description and Significance

Ralstonia insidiosa is a bacillus shaped bacterium and can be found in ponds, rivers, soils, and sludge naturally. It can also be found in drinking water, industry purified water, and most importantly, hospital water supplies. This organism is important to understand because it can cause sepsis and other infections in patients within hospital settings.

Genome Structure

This bacteria has two circular chromosomes, one being primary that contains 4 million base pairs, and the other being secondary that contains 2 million base pairs. It also has one 50 kb plasmids. It contains 16S rRNA.

Cell Structure, Metabolism and Life Cycle

It is: aerobic, oxidase positive, gram negative, and classified as a non fermentative bacillus. It is a chemoheterotroph that relies on other carbon sources for cell growth. R. insidiosa can use hydrocarbons from chemical compounds normally found in disinfectants as a source of carbon. It can also do this in hypoxic environments.

Ecology and Pathogenesis

It does not normally affect healthy humans, but those who are already immunocompromised. It is normally found in hospitals and in the lungs of patients that have cystic fibrosis. Patients normally are infected via contaminated water and sterile products. This happens because R. insidosa is very small and is able to pass through 0.2mm filters that are used for sterilization.

References

Fang, Qingqing, et al. “Nosocomial Bloodstream Infection and the Emerging Carbapenem-Resistant Pathogen Ralstonia Insidiosa - BMC Infectious Diseases.” BioMed Central, BioMed Central, 23 Apr. 2019, https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-019-3985-4.

Ryan, Michael P., and Catherine C. Adley. “The Antibiotic Susceptibility of Water-Based Bacteria Ralstonia Pickettii and Ralstonia Insidiosa.” Journal of Medical Microbiology, Microbiology Society, 1 July 2013, https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.054759-0.

Xu, Yunfeng, et al. “Genome Sequences of Ralstonia Insidiosa Type Strain ATCC 49129 and Strain FC1138, a Strong Biofilm Producer Isolated from a Fresh-Cut Produce-Processing Plant.” Genome Announcements, U.S. National Library of Medicine, 18 Aug. 2016, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991715/#:~:text=It%20contains%205%2C820%20protein%2Dcoding,large%20plasmid%20(50%2C770%20bp).

Author

Page authored by Samarah Jeffrey, student of Prof. Bradley Tolar at UNC Wilmington.