Cyclospora cayetanensis

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Microbiology in Italy[1]

Etiology/Bacteriology

Taxonomy

| Domain = Eukaryota | Phylum = Apicomplexa | Class = Coccidia | Order = Eucoccidiorida | Family = Eimeriidae | Genus = Cyclospora | species = C. cayetanensis

NCBI: [2]

Diagnosis

The first step in diagnosis of Cyclospora cayetanensis infection should be when health care providers notice the symptom of prolonged diarrhea in the patient, and should also look at the other symptoms associated with the disease as well. If the patient has recently traveled to a tropical or sub-tropical area that is known for causing infection, the healthcare provider should ask the patient for a stool sample 3 However, because testing for Cyclospora is not usually done in most laboratories in the US when the stool is tested for parasites, identification for C. cayetanensis in the stool requires special lab tests not routinely done, therefore this microorganism can be difficult to diagnose, especially when it comes to laboratory tests. This is because even if an infected patient is symptomatic, there may not be enough oocysts in the stool to detect infection in lab examinations; therefore it is not uncommonly needed for the patient to provide multiple stool specimens ranging within several days. 2 Identification of this organism can be made through microscopic techniques, usually several different stains, such as Acid-fast stains, or using an epifluorescence microscope, in which the the Cyclospora oocyst appear a neon-blue color. 1 Due to the face that Cyclospora cayetanensis is unable to be culture in the laboratory and its small size, it is near impossible to detect and isolate the organism on the contaminated food since the amount of organisms on it are so low. 3

Treatment

The specific drug treatment for disease caused by Cyclospora cayetanensis is the combination of two antibiotics—trimethoprim and sulfamethoxazole (co-trimaxazole), which are also sold under the names of Bactrim, Cotrim, or Septra, and symptoms can diminish within the next several days. 8 Unfortunately, there have been no alternative drug treatment options that have been effective for patients that suffer from a sulfa allergy or do not respond to the combination antibiotic. 2 Of course anti-diarrheal medication can be given by a health care provider to reduce the diarrheal symptom, but this does not actually combat against the microorganism. Hydration and rest are also essential to patients with diarrhea, and in most healthy individuals the infection can be self-limiting, and most can recover in a few days, or possibly a month or longer. 2 If left untreated the protracted diarrhea can lead to severe dehydration, and in cases like these hospitalization may occur.