User:S4350566: Difference between revisions
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References examples | References examples | ||
1. [http://dnaresearch.oxfordjournals.org/content/15/4/215.long | 1. [http://dnaresearch.oxfordjournals.org/content/15/4/215.long Naito, M., Hirakawa, H., Yamashita, A., Ohara, N., Shoji, M., Yuritake, H., Nakayama, K., Toh, H., Yoshimura, F., Kuhara, S., Hattori, M., Hayashi, T., Nakayama, K. (2008) Determination of the Genome Sequence of Porphyromonas gingivalis Strain ATCC 33277 and Genomic Comparison with Strain W83 Revealed Extensive Genome Rearrangements in P. gingivalis. DNA Res <b>4</b>:215-225. ] | ||
bold number - issue/volume? | bold number - issue/volume? |
Revision as of 06:13, 31 August 2016
Louise Parker Bench D 31/08/2016 [1]
Classification
Higher order taxa
Bacteria – Domain – Bacteroidetes – Bacteroidetes – Bacteroidales – Porphyromonadaceae – Porphyromonas
Species
Porphyromonas gingivalis and type strain (consult LPSN http://www.bacterio.net/index.html for this information)
Description and significance
Give a general description of the species (e.g. where/when was it first discovered, where is it commonly found, has it been cultured, functional role, type of bacterium [Gram+/-], morphology, etc.) and explain why it is important to study this microorganism. Examples of citations [1], [2]
Porphyromonas gingivalis is a Gram-negative anaerobe. It is a major causative agent of the initiation and progression of periodontal disease, a main cause of tooth loss [1]. It is often found in deep periodontal pockets.
Genome structure
Select a strain for which genome information (e.g. size, plasmids, distinct genes, etc.) is available.
The Porphyromonas gingivalis strain W83 has a 2,343,479bp genome sequence. It has an average G+C content of 48.3%. 1,990 open reading frames were identified in the genome, making up 85% of the genome. 1,075 of these were assigned biological role categories. - (Complete Genome Sequence of the Oral Pathogenic Bacterium Porphyromonas gingivalis Strain W83)Distinct genes
Cell structure and metabolism
Cell wall, biofilm formation, motility, metabolic functions.
Ecology
Aerobe/anaerobe, habitat (location in the oral cavity, potential other environments) and microbe/host interactions.
Pathology
Do these microorganisms cause disease in the oral cavity or elsewhere?
Application to biotechnology
Bioengineering, biotechnologically relevant enzyme/compound production, drug targets,…
Current research
Summarise some of the most recent discoveries regarding this species.
References
References examples
bold number - issue/volume?
- ↑ MICR3004
This page is written by Louise Parker for the MICR3004 course, Semester 2, 2016