Parvovirus B19: Difference between revisions
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<i>Parvoviridae</i> | <i>Parvoviridae</i> | ||
== | ==Genome Structure== | ||
The <i>Parvovirus</i> genome is a single strand of DNA with 5,596 nucleotides, 4,830 of which are coding regions.<ref name=ncbi/> This region contains 2 large open reading frames.<ref name=ncbi/> One large non-structural protein is coded by one open reading frame, and the second reading frame codes for 2 capsid proteins.<ref name=ncbi/> <br> | |||
<br> | <br> | ||
Revision as of 19:32, 25 March 2024
Background
By Grace Potter
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Parvovirus B19 is the only member of the Parvoviridae family that has been found to infect human hosts.[1] It was discovered in 1974, when a research group looking at hepatitis B surface antigens found a serum sample with unexpected results.[1] Another lab in Japan described a similar virus in 1979 that they called "Nakatami".[1] When compared, the two were found to be identical.[1]
In 1985 this virus was officially recognized as a member of the Parvoviridae family due to its similarities in genome size and density.[1]
Section 1
Include some current research, with at least one figure showing data.
Parvoviridae
Genome Structure
The Parvovirus genome is a single strand of DNA with 5,596 nucleotides, 4,830 of which are coding regions.[1] This region contains 2 large open reading frames.[1] One large non-structural protein is coded by one open reading frame, and the second reading frame codes for 2 capsid proteins.[1]
Section 3
Include some current research, with at least one figure showing data.
Section 4
Conclusion
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Heegaard, E.D. and Brown, K.E. "Human Parvovirus B19." 2002. Clinical Microbiology Review 15(3):485-505.
- ↑ Bartlett et al.: Oncolytic viruses as therapeutic cancer vaccines. Molecular Cancer 2013 12:103.
- ↑ Cite error: Invalid
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Authored for BIOL 238 Microbiology, taught by Joan Slonczewski,at Kenyon College,2024
