Bordetella parapertussis: Difference between revisions
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Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? | Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? | ||
The genome of Bordetella parapertussis typically consists of a single circular chromosome. The size of this genome is approximately 4.7 million base pairs (Mbp), with a G+C content of around 65%. Comparative genomic studies have revealed ongoing evolutionary changes, with the identification of single nucleotide polymorphisms and short insertions and deletions compared to reference genomes. | |||
B. parapertussis has diverged into two distinct lineages: one that causes whooping cough in infants and another that infects sheep. Unlike B. pertussis, B. parapertussis is oxidase-negative, indicating differences in respiratory mechanisms. | |||
The genome annotation of a recently sequenced B. parapertussis isolate from Iran, IRBP134, revealed approximately 4,620 potential coding sequences and 55 RNA sequences, including 63 tRNAs, as well as one large and one small subunit of ribosomal RNA. The genome assembly generated 72 scaffolds with an N50 value of 106,547. [9] | |||
==Cell Structure, Metabolism and Life Cycle== | ==Cell Structure, Metabolism and Life Cycle== |
Revision as of 06:11, 24 April 2024
Classification
Domain: Bacteria
Phylum: Proteobacteria
Class: Betaproteobacteria
Order: Burkholderiales
Family: Alcaligenaceae
Genus and Species: Bordetella parapertussis [1]
Species
Bordetella parapertussis
Description and Significance
Describe the appearance, habitat, etc. of the organism, and why you think it is important.
Genome Structure
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence?
The genome of Bordetella parapertussis typically consists of a single circular chromosome. The size of this genome is approximately 4.7 million base pairs (Mbp), with a G+C content of around 65%. Comparative genomic studies have revealed ongoing evolutionary changes, with the identification of single nucleotide polymorphisms and short insertions and deletions compared to reference genomes.
B. parapertussis has diverged into two distinct lineages: one that causes whooping cough in infants and another that infects sheep. Unlike B. pertussis, B. parapertussis is oxidase-negative, indicating differences in respiratory mechanisms.
The genome annotation of a recently sequenced B. parapertussis isolate from Iran, IRBP134, revealed approximately 4,620 potential coding sequences and 55 RNA sequences, including 63 tRNAs, as well as one large and one small subunit of ribosomal RNA. The genome assembly generated 72 scaffolds with an N50 value of 106,547. [9]
Cell Structure, Metabolism and Life Cycle
Interesting features of cell structure; how it gains energy; what important molecules it produces.
Ecology and Pathogenesis
Habitat; symbiosis; biogeochemical significance; contributions to environment.
If relevant, how does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
References
[1] [Schoch CL, et al. NCBI Taxonomy: a comprehensive update on curation, resources and tools. Database (Oxford). 2020: baaa062. PubMed: 32761142 PMC: PMC7408187]
[9] Safarchi, A., Saedi, S., Tay, C. Y., Lamichhane, B., Nakhost Lotfi, M., & Shahcheraghi, F. (2022). Genome Characteristic of Bordetella parapertussis Isolated from Iran. Current microbiology, 79(10), 314. https://doi.org/10.1007/s00284-022-03009-x
Author
Page authored by Sachin Gupta and Erin Goertzen, students of Prof. Jay Lennon at Indiana University.