Clostridium acetobutylicum: Difference between revisions
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==Description and significance== | ==Description and significance== | ||
Clostridium acetobutylicum is a Gram positive bacillus. It is anaerobic and saccharolytic capable of producing a number of different commercially useful products; most notably acetone, ethanol and butanol. | |||
It was first isolated between 1912 and 1914. Chaim Weizmann cultured the bacteria to be used to produce acetone, ethanol and butanol (ABE method) which was used to produce TNT and gunpowder in the first World War. | |||
Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. | Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. | ||
Include a picture or two (with sources) if you can find them. | Include a picture or two (with sources) if you can find them. | ||
Nolling J et al., "Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum.", J Bacteriol, 2001 Aug;183(16):4823-38 | |||
==Genome structure== | ==Genome structure== | ||
Revision as of 05:51, 1 May 2007
A Microbial Biorealm page on the genus Clostridium acetobutylicum
Classification
Higher order taxa
Bacteria (Domain); Firmicutes (Phylum); Clostridia (Class); Clostridiales (Order); Clostridiaceae (Family); Clostridium (Genus)
Species
Clostridium acetobutylicum
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NCBI: Taxonomy |
Description and significance
Clostridium acetobutylicum is a Gram positive bacillus. It is anaerobic and saccharolytic capable of producing a number of different commercially useful products; most notably acetone, ethanol and butanol.
It was first isolated between 1912 and 1914. Chaim Weizmann cultured the bacteria to be used to produce acetone, ethanol and butanol (ABE method) which was used to produce TNT and gunpowder in the first World War.
Describe the appearance, habitat, etc. of the organism, and why it is important enough to have its genome sequenced. Describe how and where it was isolated. Include a picture or two (with sources) if you can find them.
Nolling J et al., "Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum.", J Bacteriol, 2001 Aug;183(16):4823-38
Genome structure
Describe the size and content of the genome. How many chromosomes? Circular or linear? Other interesting features? What is known about its sequence? Does it have any plasmids? Are they important to the organism's lifestyle?
Cell structure and metabolism
Describe any interesting features and/or cell structures; how it gains energy; what important molecules it produces.
Ecology
Describe any interactions with other organisms (included eukaryotes), contributions to the environment, effect on environment, etc.
Pathology
How does this organism cause disease? Human, animal, plant hosts? Virulence factors, as well as patient symptoms.
Application to Biotechnology
Does this organism produce any useful compounds or enzymes? What are they and how are they used?
Current Research
Enter summaries of the most recent research here--at least three required
References
Taxonomy: NCBI
Edited by Mark Hower, student of Rachel Larsen and Kit Pogliano
